Precision oncology program for advanced cancer patients
Official title: Research Collaboration for a Precision Oncology Program (POP)
Run by University of Zurich · NCT06680726 · Data updated 2026-11-12
This study is testing a new way to personalize cancer treatment for people with advanced cancer by looking closely at their tumors to see which therapies might work best for them.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | University of Zurich Academic / other |
| Locations | 1 site (Zurich) |
| Status | Recruiting |
| Started | December 11, 2023 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | November 8, 2024 |
| Trial ID | NCT06680726 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients diagnosed with solid tumors such as adenocarcinoma, squamous cell carcinoma, neuroendocrine carcinoma, or sarcoma, with an ECOG performance status of 0-2.
✕Probably not a fit
Patients with blood cancers will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The Precision Oncology Program (POP) is an observational collaboration aimed at generating insights into the individual tumor biology of patients with advanced malignancies. By utilizing innovative biotechnologies and comparing patient profiles against specific databases, the program seeks to inform clinical decision-making regarding potential treatment benefits. The study includes routine genetic testing and advanced imaging mass cytometry to capture tumor heterogeneity and predict therapy responses. This approach aims to integrate precision oncology into clinical practice effectively.
Why it matters
Potential benefit: If successful, this program could enhance personalized treatment strategies for patients with advanced cancers, potentially improving outcomes.
How similar studies have gone: Other studies have shown success with similar precision oncology approaches, indicating a promising avenue for advancing cancer treatment.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Signed informed consent * In the case of deceased persons: signed general consent * All patients with the diagnosis of a solid tumour including adenocarcinoma, squamous cell carcinoma, neuroendocrine carcinoma, sarcoma, etc * ECOG-performance status 0-2, if applicable * Willing and able to understand all project related procedures, including transfer of coded (i.e. pseudonymised) or anonymized clinical data to external partners (e.g. Roche), if applicable Exclusion Criteria: * Patients with the diagnosis of blood cancer.
Where it's running
-
University Hospital Zürich (Universitätsspital Zürich)
Zurich, Switzerland Recruiting
Study contacts
- Study coordinator: Andreas Wicki, Professor
- Email: andreas.wicki@usz.ch
- Phone: +41 44 255 38 99
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Long-term outcomes after vacuum-induced tamponade for postpartum hemorrhage
This study will look at women who had postpartum hemorrhage treated with vacuum-induced tamponade at a Zurich hospital to see how they fared over time, including future pregnancies and fertility.
-
Add-on Sildenafil Before Exercise in PAH to See if Max Workload Improves
This study tests whether taking 20 mg sildenafil right before exercise helps people with pulmonary arterial hypertension perform more work during cardiopulmonary testing.
-
Fatigue Investigation Using Digital Outcomes
This study tests whether digital monitoring with a smartphone app and wearables can track fatigue in people with MS or long COVID, compared with healthy volunteers.
-
Impact of ambient air vs nasal liquid oxygen on exercise performance in pulmonary vascular disease
This study tests whether using nasal liquid oxygen during a 6-minute walk test changes how far patients with PAH or CTEPH can walk compared to breathing room air.
-
Liquid oxygen vs ambient air during a 6-minute walk in people with pulmonary vascular disease
This study tests whether walking with liquid oxygen at about 4 L/min helps or hinders distance walked compared with walking on room air in adults with PAH or CTEPH living in Switzerland.
-
Daily adjustment of radiation dose in MRI-guided SBRT for abdominal and pelvic tumors
This trial tests whether adjusting the radiation dose in real-time during MRI-guided SBRT improves targeting for abdominal or pelvic tumors.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.