Understanding the causes of primary immune deficiencies

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the pathophysiology of primary immunodeficiencies (PID), which are conditions that lead to increased susceptibility to infections and inflammatory responses. Researchers will collect and analyze various biological samples, including stool, urine, blood, tissue biopsies, and bone marrow, to assess anti-microbial activity and inflammatory responses. The findings may pave the way for the development of targeted treatments tailored to the specific underlying causes of different PIDs.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinical diagnosis of an inborn error of immunity (primary immunodeficiency, PID)
* Clinically healthy (non-age matched) volunteer

Exclusion Criteria:

* exclusion of an inborn error of immunity
* secondary immunodeficiency
* refusal to enter the study

Where it's running

• University Children's Hospital Zurich
  Zurich, Switzerland Recruiting

Study contacts

• Principal investigator: Janine Reichenbach, Prof. Dr. — University Children's Hospital, Zurich
• Study coordinator: Janine Reichenbach, Prof. Dr.
• Email: janine.reichenbach@kispi.uzh.ch
• Phone: +41442667311

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Using specialized T-cells to treat adenovirus infections in patients with immune deficiencies

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.