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Clinical trials and research at University of Wisconsin-Madison

• 141Clinical trials
• 1330NIH research projects
• 1New in 30 days
• 7Countries

Newest trials

All recruiting trials (141)

• 18F-FES PET/MRI to find hidden disease in invasive lobular breast cancer

  This study tests whether adding 18F-FES PET/MRI can reveal more disease in lobular breast cancer than standard imaging alone.

  Recruiting Phase 4 University of Wisconsin, Madison · Madison, Wisconsin · NCT07910474

• Share or Not to Share: A Peer-Led Support Program for Caregivers of Autistic Young Adults

  A group, peer-led program tests how six virtual sessions can support family caregivers of autistic young adults (ages 18–26) in navigating roles, sharing experiences, and planning for the future.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07856927

• Decision-support tool to aid blood biomarker testing discussions in primary care

  A brief tool is being tested to help primary care doctors talk with patients about blood biomarker testing for Alzheimer's disease and support shared decision-making.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07812337

• Durvalumab plus histotripsy for intrahepatic cholangiocarcinoma

  This study tests whether adding histotripsy to ongoing durvalumab helps people with advanced intrahepatic cholangiocarcinoma by boosting the immune response and checking safety.

  Recruiting Phase 2 University of Wisconsin, Madison · Madison, Wisconsin · NCT07766187

• Proton Therapy Treatment-Planning Software: Checking How Well RayStation and RayCare Work in Real Care

  This study tests whether the RayStation 2025 and RayCare 2025 software upgrades reliably support delivering standard proton therapy to adults.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07759999

• See if informal tick education helps kids ages 6-12

  The study tests simple educational activities about ticks for children aged 6 to 12 to see how it changes their attitudes and knowledge.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07756606

• Multiplanar, high-frequency brain stimulation with personalized targeting

  This study tests a non-invasive brain stimulation method called TES-TI to see if it can briefly change brain activity in healthy adults using personalized electrode placements.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07752745

• Neuro-MoD: Using taVNS and CIMT to help movement in infants with perinatal brain injury

  This study tests whether a 40-hour program of constraint-induced movement therapy plus transcutaneous auricular vagus nerve stimulation can improve use of the weaker arm in infants aged 8 to 24 months after perinatal brain injury.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07738432

• PCOS and Brain Health

  This study tests how PCOS may affect brain blood flow, brain structure, and thinking skills in reproductive-age people with and without PCOS.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07727512

• Eccentric Hamstring Training vs Sprint-Specific Training for Hamstring Performance in Young Athletes

  This study tests whether three hamstring training approaches (eccentric, sprint-based, and Romanian deadlift with Nordic hamstring) improve hamstring structure and sprint-related performance in healthy young athletes.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07716319

• Overnight thalamic TES-TI to modulate sleep spindles in schizophrenia and matched healthy controls

  This study tests whether a noninvasive brain stimulation method during sleep can change sleep spindles in people with schizophrenia spectrum disorders and in healthy adults.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07680114

• Ways to Boost Quadriceps Power After ACL Surgery

  This study tests whether neuromuscular electrical stimulation or hamstring vibration can help people 2–4 months after ACL reconstruction increase their quadriceps strength.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07674784

• The ENHANCE Project Toolkit

  This pilot study tests a bundle of smartphone and online tools to help people who use drugs reduce overdose risk.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07649278

• Brain health changes after gender-affirming hormone therapy in transgender adults

  This study tests how starting gender-affirming hormone therapy may affect brain blood flow, structure, connectivity, and cognitive function in transgender adults.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07624747

• Brain blood flow and brain regulation in critically ill kids

  This study tests how blood flow in the brain behaves in critically ill children using a noninvasive ultrasound (TCD) to see if brain autoregulation patterns relate to outcomes.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07613918

• Is CSE-MRI as good as FLT PET for spotting active bone marrow in men with advanced prostate cancer

  This study tests whether a special MRI method can match FLT PET in telling active bone marrow from inactive bone marrow in men with metastatic, treatment‑resistant prostate cancer who are receiving Lu-177 PSMA therapy.

  Recruiting Early Phase 1 University of Wisconsin, Madison · Madison, Wisconsin · NCT07609225

• Optimizing Smart Messaging for Alcohol Recovery

  A smartphone-based program tests whether tailored recovery messages can help people with alcohol use disorder stay engaged with support resources and improve health outcomes.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07573540

• Accessible care model comparing nurse-led versus physician-led transition education for teens and young adults with congenital heart disease

  This project will test whether an accessible care model and nurse-led versus physician-led transition education helps teens and young adults (ages 12–26) with congenital heart disease move successfully from pediatric to adult heart care.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07559253

• AI-assisted, patient-friendly imaging report summaries to improve communication of cancer imaging results

  This project will try AI-written, easy-to-understand summaries of scan results for adults with current or past cancer who get imaging at UW Health to see if they help patients understand results and feel less anxious.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07532083

• Detecting consciousness using a small TMS-EEG setup and the Presence-IP1.0 algorithm

  This project will try the Presence-IP1.0 algorithm with a reduced-channel TMS-EEG setup to see if it can tell when healthy adults are awake and conscious versus asleep.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07523191

• Thumbs-up for TI-TES during sleep: testing thalamic stimulation to boost sleep spindles in healthy adults

  We’re testing a non-invasive brain stimulation method during sleep to see if it can increase sleep spindle activity in healthy adults.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07498270

• ORIGIN-FH: Newborn screening to detect familial high cholesterol

  This project will test a genetic cheek swab of parents plus blood screening of newborns to find familial high cholesterol in babies born to parents with familial hypercholesterolemia.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07470723

• Exercise effects on carotid artery function in young adults with metabolic syndrome

  This study will test if a single 30-minute bout of moderate exercise can quickly improve internal carotid artery endothelial function in young adults with metabolic syndrome and whether effects differ by sex.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07430839

• A program to help Black adults quit smoking

  This trial tests three different, culturally tailored smoking-cessation approaches to see which helps Black adults quit smoking over 26 weeks.

  Recruiting Phase 4 University of Wisconsin, Madison · Phoenix, Arizona and 4 other locations · NCT07419425

• Biomarkers in infants with prior neonatal brain injury

  This project will test brain activity and development using games, EEG, and parent questionnaires in infants aged 3–24 months with and without prior neonatal brain injury.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07413900

• Gut Probiotic Study for Alzheimer’s-related Dementia and At-risk Adults

  Researchers will test whether a probiotic supplement is safe and feasible for people with dementia or mild cognitive impairment due to Alzheimer’s, and for some with normal cognition but at risk, over up to a year.

  Recruiting Phase 1 University of Wisconsin, Madison · Madison, Wisconsin · NCT07413744

• Sparking Potential — revealing early infant thinking and brain development

  For infants aged 3–24 months with or without perinatal brain injury, this project sees if online games and parent questionnaires can reveal early cognitive and developmental differences.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07390136

• Biomarkers for oral cavity cancer response to neoadjuvant immunotherapy using patient-specific tumor cultures

  This will test whether a patient-specific tumor culture can predict how people with oral cavity cancer respond to pembrolizumab given before surgery.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07343596

• RHINO study: understanding rhinovirus causes of severe respiratory illness in kids

  This study tests how rhinoviruses contribute to severe respiratory illness in young children by following healthy kids and hospitalized patients to see how nasal viruses and gene activity relate to symptoms.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07342582

• Prophylactic TCRαβ+/CD19+- Depleted Donor Lymphocyte Infusion After Allogeneic Stem Cell Transplant in High-Risk Blood C cancers

  A safety-driven test to see if a specially prepared donor lymphocyte infusion given after an allogeneic stem cell transplant is tolerable and safe in patients with high-risk hematologic malignancies.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07285668

• Group Cognitive Processing Therapy (CPT) for incarcerated adults with PTSD

  This project will try group Cognitive Processing Therapy (CPT) with incarcerated adults who have PTSD to see if it reduces PTSD symptoms and disciplinary incidents.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07283757

• HEPZATO KIT with Opdualag for metastatic melanoma that has spread to the liver

  This will try adding HEPZATO KIT to Opdualag (nivolumab + relatlimab) to see if it's safe and helps people with metastatic melanoma that has spread to the liver.

  Recruiting Phase 1/2 University of Wisconsin, Madison · Madison, Wisconsin · NCT07281924

• Comparing support options for the Healthy Minds meditation app

  This study tests whether adding a brief coaching session, on-demand email help, or short microsupport messages helps adults with elevated depression or anxiety get more benefit from the Healthy Minds meditation app.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07278466

• See if extra caffeine helps preterm babies with kidney oxygen problems

  This study tests whether giving additional caffeine to very premature babies with low kidney oxygen levels can improve kidney health without harming the brain.

  Recruiting Phase 2 University of Wisconsin, Madison · Madison, Wisconsin · NCT07262060

• How hearing aids help in everyday noisy places

  This project tests whether different hearing aid settings and everyday noisy situations change how well hearing aids help adults with symmetric, adult-onset sensorineural hearing loss who already use hearing aids.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07226167

• Scaling medications for opioid use disorder across U.S. prisons

  This project will test two ways to increase use of medications for opioid use disorder in prisons to help incarcerated people stay safer and healthier during incarceration and reentry.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07224516

• Exercise before cognitive behavioral therapy for depression (CBT+)

  This study will test whether doing moderate aerobic exercise right before CBT helps adults with major depressive disorder by improving therapy engagement and reducing depressive symptoms.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07221929

• Temporal interference to change thalamocortical activity and brain network connectivity

  This trial will test whether a patterned, noninvasive electrical stimulation can temporarily change how the thalamus and cortex communicate in healthy adults during sleep and wakefulness.

  Recruiting Phase 1 University of Wisconsin, Madison · Madison, Wisconsin · NCT07219719

• Adding Y‑NM600 imaging and targeted Y‑90 radiation to anti‑PD‑1/PD‑L1 treatment for metastatic cancer

  This will test whether giving radioactive Y‑NM600 imaging and a targeted Y‑90 radiation dose to people with metastatic cancer who are on anti‑PD‑1 or anti‑PD‑L1 medicines is safe and can help those medicines work better.

  Recruiting Phase 1 University of Wisconsin, Madison · Madison, Wisconsin · NCT07197671

• CT‑XPI: a contrast‑free CT method to map lung perfusion

  This trial will test whether a new contrast‑free, high‑frame‑rate CT method (CT‑XPI) can show lung perfusion better than standard CT scans in adults having a clinically indicated CT.

  Recruiting Phase 2 University of Wisconsin, Madison · Madison, Wisconsin · NCT07192133

• Improving speech clarity in children with cerebral palsy using augmentative communication

  This test checks whether having children with cerebral palsy point to letters or pictures while they speak can make their speech easier to understand.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07173049

• Mastisol to help casts stay on for infants with bilateral clubfoot

  This trial tests whether applying Mastisol adhesive before casting helps infants with bilateral clubfoot keep their casts on, shorten treatment, and reduce complications during casting and up to five years afterward.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07154550

• Oneida Nation cultural nutrition and wellness program to reduce stroke risk

  This program will try culturally based nutrition, school education, and wellness coaching for Oneida Nation members ages 7–85 to see if it lowers stroke risk factors and slows vascular cognitive decline.

  Recruiting at 2 sites University of Wisconsin, Madison · Madison, Wisconsin and 1 other locations · NCT07139132

• How chemotherapy given before surgery affects thinking and memory in ovarian cancer

  This study will test whether chemotherapy given before surgery affects thinking and memory in people with newly diagnosed advanced epithelial ovarian cancer.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07125209

• DNA vaccine plus nivolumab and targeted radiation for recurrent oligometastatic prostate cancer

  This study will try a DNA vaccine called pTVG-HP together with the checkpoint blocker nivolumab and targeted radiation to see if they can eliminate metastatic tumors in men with non-castrate, recurrent oligometastatic prostate cancer.

  Recruiting Phase 1 University of Wisconsin, Madison · Madison, Wisconsin · NCT07090148

• How childhood adversity and SIRT1 affect early blood vessel aging.

  This project will test whether taking nicotinamide riboside can boost SIRT1 and improve blood vessel function in 18–30-year-olds with high levels of childhood adversity compared with those with no ACEs.

  Recruiting University of Wisconsin, Madison · Iowa City, Iowa and 1 other locations · NCT07073352

• FDG PET/MRI to find causes of ongoing hip pain after arthroscopy

  This trial will try a single FDG PET/MRI scan to see if it can find inflammation or other problems in adults 18–45 who still have moderate to severe pain at least six months after one hip arthroscopy.

  Recruiting Phase 2 University of Wisconsin, Madison · Madison, Wisconsin · NCT07066709

• Non-invasive trigeminal nerve stimulation to improve brain fluid flow and slow cognitive decline

  This trial will try mild, non-invasive stimulation of a head nerve (the trigeminal nerve) to see if it improves cerebrospinal fluid flow and waste clearance in adults with recent mild traumatic brain injury and in healthy volunteers.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT07044596

• Improving communication between cancer patients and providers with TrialTalk™

  This project will test whether online TrialTalk™ training helps adult cancer patients and their hematology/oncology providers communicate more clearly during routine clinic visits.

  Recruiting University of Wisconsin, Madison · Chicago, Illinois and 2 other locations · NCT06985953

• Evaluating a Neurologic Assessment Scale for Pediatric Brain and Spine Tumors

  This study is testing a new neurologic exam scale for kids with brain and spine tumors to see how consistently different doctors can use it to check their progress, including doing some assessments through telemedicine.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06981156

• Mindfulness-based well-being skills for people reentering the community

  This trial tests a six-week mindfulness program to see if it reduces anxiety and depression and is acceptable for adults returning to the community after incarceration.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06975657

• Airflow and vocal function measurements for children and adults with healthy voices

  This project will test three child-friendly airflow measurement methods to see which work best for assessing voices in children and to compare healthy and disordered pediatric voices.

  Recruiting University of Wisconsin, Madison · Iowa City, Iowa and 1 other locations · NCT06975046

• Measuring blood flow during liver embolization procedures

  This study is testing a new method to measure blood flow in patients getting liver embolization to see if it helps make treatments for liver tumors more effective.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06971991

• Worldwide yearly screening and care planning for males treated for hypospadias

  This project will test whether the WYSH web app's Care Planning Tool is a practical and acceptable way to support boys and men who had hypospadias repair.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06966375

• FAPI PET/MRI for non-invasive measurement of lung fibrogenesis

  This project will test whether FAPI PET/MRI scans can detect active scarring in adults with fibrotic lung diseases such as idiopathic pulmonary fibrosis or fibrotic hypersensitivity pneumonitis.

  Recruiting Phase 2 University of Wisconsin, Madison · Madison, Wisconsin · NCT06940427

• Creating a dataset for Age-Related Macular Degeneration imaging

  This study is collecting eye images from people aged 50 and older to see if a new AI tool can help spot early signs of Age-Related Macular Degeneration and prevent vision loss.

  Recruiting at 13 sites University of Wisconsin, Madison · Atlanta, Georgia and 14 other locations · NCT06924021

• Couples' Affect in Relationships: Testing a Well-Being App for Couples

  We’re testing whether using a well-being mobile program with one partner in a long-term relationship can improve both partners’ happiness and relationship satisfaction.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06907654

• Dairy Choline Availability: Is WPPC a match for eggs in postmenopausal women?

  This study tests whether whey protein phospholipid concentrate (WPPC) provides choline as well as whole eggs for postmenopausal women.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06902480

• An app to educate and change behaviors regarding tick bites

  This study is testing a smartphone app that helps people learn about tick bites and change their habits to prevent tick-borne diseases.

  Recruiting at 4 sites University of Wisconsin, Madison · Urbana, Illinois and 3 other locations · NCT06880692

• CBD for bladder control after spinal cord injury

  This test gives adults with recent supra‑sacral spinal cord injury purified CBD (Epidiolex) twice daily for 90 days to see if it reduces urinary incontinence and other bladder symptoms.

  Recruiting Phase 2 University of Wisconsin, Madison · Madison, Wisconsin · NCT06840899

• Study on Pediatric Autoimmune Neuropsychiatric Disorders Linked to Streptococcus

  This study is looking at how common certain neuropsychiatric disorders are in children aged 3-17 and how they might be linked to a specific type of bacteria called Group A streptococcus.

  Recruiting at 2 sites University of Wisconsin, Madison · Lebanon, New Hampshire and 1 other locations · NCT06811935

• Calls and coordination to connect people to care after prison release

  This program will test whether short weekly phone check-ins with a Nurse Case Manager help people leaving prison who have substance use history and chronic medical or psychiatric conditions get more non-emergency outpatient clinic visits.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06794983

• Pediatric eCART: an electronic tool to spot children at high risk of critical illness

  This project will test whether implementing pediatric eCART, an EHR-based risk alert system, helps identify hospitalized children at high risk of life-threatening deterioration and is acceptable to pediatric nurses.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06771830

• Using AI to prevent vision loss from diabetes in underserved communities

  This study is testing a new AI program to see if it can help people with diabetes in underserved communities get better eye care and follow-up after screenings.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06763952

• Examining bone density changes after knee replacement surgery

  This study is testing how knee replacement surgery affects bone density in the thigh bone for people using different types of implants and surgical methods over a year.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06733597

• Improving access to children's medical notes for parents during hospitalization

  This study tests whether giving parents real-time access to their child's medical notes on a tablet during hospitalization can help them be more involved in their care and spot any safety issues.

  Recruiting at 2 sites University of Wisconsin, Madison · Los Angeles, California and 2 other locations · NCT06722378

• Using ultrasound to check fetal lung health

  This study is testing if a special ultrasound can help check the lung health of babies in the womb during the last few months of pregnancy.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06722365

• Testing a new ankle brace for athletes

  This study is testing a new ankle brace for athletes to see if it helps them perform better and feel more comfortable while running and making quick movements.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06719609

• Midazolam with psilocybin for mild declines in emotional wellbeing

  This trial will see if different doses of psilocybin, given with midazolam or placebo, can boost emotional wellbeing in adults who have experienced a modest drop in wellbeing.

  Recruiting Phase 1 University of Wisconsin, Madison · Madison, Wisconsin · NCT06692192

• Evaluating prostate cancer using FAPI PET/MRI scans

  This study is testing if a special type of scan can help doctors better diagnose and monitor prostate cancer in patients who already have the disease.

  Recruiting Phase 2 University of Wisconsin, Madison · Madison, Wisconsin · NCT06675357

• Tranexamic acid to reduce bruising after facial filler injections

  This will test whether adding tranexamic acid to hyaluronic acid injections reduces bruising, swelling, and tenderness in adults getting facial fillers.

  Recruiting Phase 2 University of Wisconsin, Madison · Madison, Wisconsin · NCT06665594

• Training surgeons to improve communication with patients in Wisconsin

  This study is testing a new training program for surgeons in Wisconsin to see if it helps them communicate better with patients about surgery and treatment choices.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06647303

• Virtual intervention for at-risk children with neurological issues

  This study is testing if a virtual program can help young children with neurological issues, like those born prematurely, just as well as in-person help does.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06643598

• How younger adults' brain blood vessels respond to changes in blood flow

  We will use MRI to test how brain blood flow changes during a simulated postural shift and while breathing more carbon dioxide in healthy adults aged 20–40, and whether prazosin changes those responses.

  Recruiting Phase 2 University of Wisconsin, Madison · Madison, Wisconsin · NCT06629090

• How brain blood vessels respond to changes in blood flow

  This project will test how brain blood flow changes during a simulated postural change and when breathing higher levels of carbon dioxide in adults aged 55–69.

  Recruiting Phase 2 University of Wisconsin, Madison · Madison, Wisconsin · NCT06629077

• Meditation app to help teens with depression

  This study is testing whether a meditation app can help teens aged 14 to 19 feel less depressed compared to using a water tracking app for eight weeks.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06626425

• Effects of e-cigarette use on health

  This study is trying to see how using e-cigarettes affects heart and lung health over time in people who use them compared to those who don’t.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06610838

• Neuromodulation-assisted Ego-disengagement (NEURO-EGO Stage 2)

  This trial tests whether short sessions of non-invasive brain stimulation can help healthy adults new to meditation enter a meditative, ego-disengaged state more quickly and improve openness and wellbeing.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06601699

• Using brain stimulation to enhance meditation experiences

  This study is testing if brain stimulation can help experienced meditators reach deeper meditation states more easily and quickly.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06601686

• Investigating nicotine pouches and mini lozenges as alternatives to smoking

  This study is testing if nicotine pouches and mini lozenges can help smokers who aren't ready to quit cigarettes yet by giving them alternatives to try for a week.

  Recruiting Phase 4 University of Wisconsin, Madison · Madison, Wisconsin · NCT06595459

• Implementation of a Primary Hospital Provider team to improve patient care

  This study is testing whether having a dedicated Primary Hospital Provider team can help patients with complex health needs get better care and fewer hospital visits.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06581224

• Using celecoxib for pain management after parotid surgery

  This study is testing if taking celecoxib with Tylenol can help manage pain after parotid surgery and reduce the need for stronger painkillers like oxycodone.

  Recruiting Phase 2 University of Wisconsin, Madison · Madison, Wisconsin · NCT06505187

• Helping dual users of cigarettes and e-cigarettes quit smoking

  This study is testing different ways to help people who smoke both cigarettes and e-cigarettes quit for good by using medications and counseling.

  Recruiting Phase 4 University of Wisconsin, Madison · Madison, Wisconsin · NCT06474299

• Identifying brain recovery markers in stroke patients with aphasia

  This study is trying to find out how brain recovery affects language skills in stroke patients with aphasia to help improve their treatment and recovery.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06471127

• Using letermovir to prevent CMV infection in kidney and pancreas transplant patients

  This study is testing if letermovir can help prevent CMV infections in adult kidney and pancreas transplant patients who are at high risk, while reducing their need for another medication called ganciclovir.

  Recruiting Phase 3 University of Wisconsin, Madison · Madison, Wisconsin · NCT06407232

• Injecting bone marrow cells to treat dry mouth

  This study is testing if injecting special cells from bone marrow into the salivary glands can help people with dry mouth caused by conditions like Sjögren's disease feel better.

  Recruiting Phase 1 University of Wisconsin, Madison · Madison, Wisconsin · NCT06392711

• Comparing two imaging systems for inherited retinal disease

  This study is testing whether two new eye imaging systems can provide similar information as a standard system for people with inherited retinal diseases.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06380075

• Cognitive training effectiveness in different age groups

  This study is testing if cognitive training can help improve thinking skills in both younger and older adults by having them complete tasks and answer questions over several weeks.

  Recruiting at 3 sites University of Wisconsin, Madison · Riverside, California and 2 other locations · NCT06375681

• Improving Medicaid access for those who lost coverage

  This study is testing whether live phone calls from helpers can get more people who lost their Medicaid coverage to sign up again compared to using pre-recorded calls.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06342375

• Exploring the link between sleep and emotions in teens with PTSD

  This study is testing if improving sleep quality can help teens with PTSD feel better emotionally and improve their mood during the day.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06341413

• Ultrasound imaging to assess lower urinary tract symptoms

  This study is testing a new, cost-effective ultrasound method to see how well it can measure bladder function in men with lower urinary tract symptoms and benign prostatic hyperplasia.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06323109

• Mobile app for alcohol cessation in liver disease patients

  This study is testing whether a smartphone app can help people with alcohol-related liver disease stop drinking more effectively than just regular care alone.

  Recruiting at 3 sites University of Wisconsin, Madison · Lansing, Michigan and 2 other locations · NCT06305624

• Examining how asthma affects brain function and mental health

  This study is trying to see how asthma affects brain function and mental health by comparing people with severe asthma to healthy individuals.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06299592

• Understanding how the brain controls speech in healthy individuals

  This study is trying to understand how healthy people control their speech by looking at how they adapt their speaking when they hear changes in their own voice.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06233513

• Evaluating speech patterns to understand Alzheimer's disease

  This study is testing if changes in how people speak can help spot early signs of Alzheimer's disease in those at higher risk.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06230783

• Understanding how nutrition affects growth in premature infants

  This study looks at how the food that premature babies eat in the NICU affects their growth and development over three years.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06226051

• Oh Happy Day Class – Digital Connections for Depression in African Americans

  A mobile app delivers six weekly depression-therapy classes to African American adults to see if it helps reduce depressive symptoms.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06206226

• Analyzing PET scans and blood samples in melanoma patients receiving immunotherapy

  This study is testing if early PET scans and blood tests can help predict how well immunotherapy works for people with advanced melanoma.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06199713

• Pilot program to offer comprehensive geriatric assessments before major surgery.

  This pilot will try a system-level package to see if more people aged 80 and older can get a full comprehensive geriatric assessment (CGA) before elective major surgery.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06184724

• Using PET/MRI scans to find sources of chronic pain

  This study is testing if special PET/MRI scans can help find out where chronic pain comes from in people who have ongoing pain after joint surgeries compared to those without pain.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06171659

• New imaging methods for detecting brain tumors in patients with metastasis

  This study is testing new imaging techniques to see if they can better detect brain tumors in patients who have cancer that has spread to the brain.

  Recruiting Phase 3 University of Wisconsin, Madison · Madison, Wisconsin · NCT06159335

• High‑ vs Low‑Dose Strength Training for Depression

  This study will test whether 16 weeks of higher‑dose versus lower‑dose strength (resistance) training helps adults with major depressive disorder feel less depressed.

  Recruiting University of Wisconsin, Madison · Ames, Iowa and 1 other locations · NCT06110897

• Investigating a new imaging method for breast cancer treatment response

  This study is testing a new imaging method to see if it can help predict how well women with a certain type of breast cancer respond to hormone therapy before surgery.

  Recruiting Phase 2 University of Wisconsin, Madison · Madison, Wisconsin · NCT06086704

• Comparing postoperative symptoms from different ureteral stents after kidney stone surgery

  This study is testing which type of ureteral stent causes fewer problems after kidney stone surgery for people who have had the procedure.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06083051

• Identifying biomarkers for endocrine therapy resistance in lobular breast cancer

  This study is trying to find markers in the blood that can help doctors understand how well patients with lobular breast cancer respond to hormone therapy.

  Recruiting Phase 2 University of Wisconsin, Madison · Madison, Wisconsin · NCT06067503

• Investigating eye function in babies with brain injury

  This study is trying to see how eye function in babies with brain injuries affects their development over time.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT05971446

• Investigating the effects of mTOR inhibitors on aging

  This study is testing if weekly doses of two medications, sirolimus and everolimus, can help older adults aged 55-89 improve their health as they age.

  Recruiting Phase 1 University of Wisconsin, Madison · Madison, Wisconsin · NCT05949658

• Improving diabetes management for Black and Hispanic patients

  This study is testing different types of support for Black and Hispanic adults with uncontrolled type 2 diabetes to see which helps them manage their condition better.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT05912647

• Training to improve cognitive performance through perceptual learning

  This study is testing different training methods to see if they can help improve thinking skills in younger and older adults with normal or corrected vision.

  Recruiting at 2 sites University of Wisconsin, Madison · Riverside, California and 2 other locations · NCT05894967

• Combining psilocybin with vagus nerve stimulation for enhanced memory

  This study is testing if combining a dose of psilocybin with a gentle nerve stimulation can help healthy adults with a slight drop in well-being improve their memory of insights gained during the experience.

  Recruiting Phase 1 University of Wisconsin, Madison · Madison, Wisconsin · NCT05866471

• Combining liposomal irinotecan, TAS102, and bevacizumab for advanced colorectal cancer

  This study is testing a new combination of three cancer drugs to see if it can help people with advanced colorectal cancer that hasn’t improved with other treatments.

  Recruiting Phase 2 University of Wisconsin, Madison · Madison, Wisconsin · NCT05854498

• Improving wellbeing in STEM graduate students through storytelling and mindfulness

  This study is testing whether storytelling workshops and a mindfulness app can help improve the wellbeing of graduate students in STEM fields at the University of Wisconsin-Madison.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT05826860

• Understanding CADASIL and its effects on cognitive impairment

  This study is trying to understand how CADASIL affects thinking and memory over time in people with a family history of the condition.

  Recruiting at 10 sites University of Wisconsin, Madison · Los Angeles, California and 11 other locations · NCT05677880

• Assessing treatment resistance in advanced prostate cancer using imaging

  This study is testing how well different imaging scans can help doctors see if advanced prostate cancer is becoming resistant to a specific type of treatment in men who are just starting therapy and those who are already on it.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT05647564

• Improving care for dementia patients through a new assessment tool for caregivers

  This study tests a new tool designed to help caregivers of hospitalized dementia patients improve their care and see if it works better than standard care alone.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT05592366

• Registry for people interested in CADASIL research

  This study is creating a registry of people with CADASIL or their family members to help researchers find candidates for future studies on this condition.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT05567744

• Bicalutamide for non-muscle invasive bladder cancer

  This trial tests whether the anti-androgen drug bicalutamide changes EGFR protein expression in adult men with non-muscle invasive bladder cancer.

  Recruiting at 3 sites Phase 1 University of Wisconsin, Madison · Tucson, Arizona and 5 other locations · NCT05521698

• Using music to reduce anxiety during hand surgery

  This study tests if letting patients listen to their favorite music during hand surgery can help reduce their anxiety compared to listening to standard relaxation music.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT05472909

• Using Lopinavir/Ritonavir for High-Grade Anal Neoplasia in HIV-Positive Patients

  This study is testing if a medication called lopinavir/ritonavir, given as a suppository, is safe and effective for people with HIV who have a serious condition called high-grade anal neoplasia.

  Recruiting Phase 1 University of Wisconsin, Madison · Madison, Wisconsin · NCT05334004

• Observing brain recovery in infants with perinatal stroke

  This study is trying to find signs of brain recovery in babies who had a stroke before or during birth to see how their brains develop and how early help can improve their outcomes.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT05013736

• Alpha/Beta T-cell Depleted Blood-forming Stem Cell Transplant for Children and Young Adults

  This study tests a stem cell transplant from a related or matched unrelated donor in kids and young adults, using a lab process to remove alpha/beta T cells and B cells to see if the transplant can work with less graft-versus-host disease.

  Recruiting Phase 1 University of Wisconsin, Madison · Madison, Wisconsin · NCT04806347

• Metabolic profiling in chronic lymphocytic leukemia

  This study is trying to understand how cancer cells in people with chronic lymphocytic leukemia use different fuels to see if it can help find new ways to treat the disease.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT04785989

• Program for discovering undiagnosed genetic diseases

  This study is trying to find new genetic causes for rare diseases by testing the DNA of 500 people who haven't been diagnosed yet.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT04586075

• Improving therapeutic learning for PTSD in women

  This study is testing whether a medication that affects dopamine can help women with PTSD from physical or sexual assault feel less fear during therapy.

  Recruiting Phase 2 University of Wisconsin, Madison · Austin, Texas and 1 other locations · NCT04558112

• Understanding how asthma affects brain function

  This study looks at how asthma might affect brain function and mental health by testing people with asthma through various assessments over several visits.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT04307667

• Using imaging to optimize tamoxifen treatment for metastatic breast cancer

  This study is testing if special imaging can help doctors find the best dose of tamoxifen for patients with metastatic breast cancer who have certain mutations and may not respond well to standard treatment.

  Recruiting Early Phase 1 University of Wisconsin, Madison · Madison, Wisconsin and 1 other locations · NCT04174352

• Combining Psilocybin with Buprenorphine for Opioid Use Disorder

  This study is testing if adding psilocybin to buprenorphine treatment can help adults with opioid use disorder feel better and improve their quality of life.

  Recruiting Phase 1 University of Wisconsin, Madison · Madison, Wisconsin · NCT04161066

• Combination of chemotherapy and immunotherapy for advanced esophageal and gastric cancer

  This study is testing a new combination of chemotherapy and immunotherapy to see if it helps people with advanced esophageal and gastric cancer feel better and have fewer side effects than current treatments.

  Recruiting Phase 2 University of Wisconsin, Madison · Madison, Wisconsin · NCT04150640

• MRI‑guided, dose‑escalated SBRT for liver and nearby bowel metastases

  This trial will try giving higher, MRI‑guided stereotactic radiation doses to people with liver or adjacent bowel metastases to find the safest maximum dose.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT04020276

• New quick MRI method for pediatric kidney disease

  This study is testing a new, faster MRI method for kids with kidney problems to see if it can better detect infections and damage without using radiation or injections.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT03959163

• MRI-guided radiation therapy for early breast cancer

  This study is testing a new way to give radiation therapy for early breast cancer that uses MRI to protect healthy tissue and can be done in just one week.

  Recruiting Phase 2 University of Wisconsin, Madison · Madison, Wisconsin · NCT03936478

• Investigating blood vessel changes during pregnancy

  This study is trying to see how blood vessels change during pregnancy in women with and without preeclampsia by looking at tissue samples taken during cesarean sections.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT03806283

• Treatment for tremors in kidney-pancreas transplant recipients

  This study is testing if a new medication called EnvarsusXR® can help reduce tremors in people who have received kidney-pancreas transplants within the last 3 to 5 years.

  Recruiting Phase 2/3 University of Wisconsin, Madison · Madison, Wisconsin · NCT03769298

• Understanding brain activity and postoperative delirium in older patients

  This study is trying to see how brain activity before surgery affects the chances of older patients developing confusion after major surgery.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT03124303

• Using paclitaxel to treat breast cancer with chromosomal instability

  This study is testing if a chemotherapy drug called paclitaxel can help women with breast cancer that has different levels of chromosomal instability before they have surgery.

  Recruiting at 2 sites Phase 4 University of Wisconsin, Madison · Iowa City, Iowa and 1 other locations · NCT03096418

• Evaluating fetal heart rhythms using magnetocardiography

  This study is testing a new way to check fetal heart rhythms using a special technique called magnetocardiography to see if it works better than traditional ultrasound for pregnant people.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT03047161

• Registry for evaluating the Precision Medicine Molecular Tumor Board

  This study is testing how genetic testing of tumors can help doctors make better treatment decisions for patients with blood cancers and solid tumors.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT03023202

• Motor attention training for ADHD in college students

  This study tests if adding tai chi or an exercise class to standard care can help college students with ADHD feel less distracted and improve their focus.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT02688959

• Transplantation with modified stem cells and Zoledronate for pediatric cancers

  This study is testing a new way to use modified stem cells and a drug called Zoledronate to see if it can safely help children with tough-to-treat cancers.

  Recruiting Phase 1 University of Wisconsin, Madison · Madison, Wisconsin · NCT02508038

• A device for stroke rehabilitation using brain and muscle stimulation

  This study is testing a new device that uses brain and muscle stimulation to see if it can help stroke patients recover better than traditional rehab methods.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT02098265

• Understanding Group A Streptococcus in Children

  This study is trying to understand the differences in Group A strep bacteria between kids who are sick and those who carry the bacteria without symptoms, to help improve treatment options.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT01558804

NIH-funded research (newest 40 of 1330)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• BRAVE Innovation Center for Viral Resistance in Chickens

  A center at UW–Madison aims to create chickens genetically resistant to avian viruses like H5N1 by identifying host genes involved in virus replication using genome-wide CRISPR screening.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11641869

• Center to Fight Vector-Borne Diseases in the Midwest

  A Midwest program brings researchers, public health teams, and vector-control groups together to prevent diseases spread by ticks and mosquitoes.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11626687

• Globally useful predictor for cervical cancer treatment response

  This project aims to develop a simple predictive signature to personalize treatment for locally advanced cervical cancer using easy tests and imaging.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11622628

• Neutrophil development with stem cells to understand their behavior

  Researchers are studying how neutrophils, a type of immune cell, develop from stem cells to better understand why they can help or harm in infections and inflammatory diseases.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11621102

• WREN: Expanding Research Capacity in Rural Primary Care Clinics

  A nationwide network in Wisconsin will strengthen rural primary care clinics to participate in real-world research and bring more clinical trials to communities.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11618649

• Targeting early oral GVHD to improve mouth health after stem cell transplant

  A study at UW–Madison will explore why some transplant patients develop painful oral GVHD and test ideas to prevent and lessen mouth-related problems.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11616478

• SSRI use during pregnancy: effects on placental blood flow and inflammation

  This grant studies how antidepressants (SSRIs) used during pregnancy might affect the placenta and inflammation, and whether a 5-HT2 receptor blocker could mitigate any negative effects.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11608163

• Targeting heart rhythm: how hERG channels regulate electrical activity

  This grant studies how the hERG potassium channel controls heart rhythm and how specially designed antibodies could help fix abnormal heartbeats.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11605224

• SEED Follow-up Studies for Autism Across Childhood and Adolescence

  A large U.S. study follows children with autism and related groups to understand how autism changes from early childhood through adolescence and beyond.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11586976

• AI-powered predictions to prevent deaths and rehospitalizations from substance misuse

  A multimodal AI model will forecast who is at risk of dying or needing another hospital visit after discharge among people who misuse substances, using a large, integrated data platform.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11556682

• HIV-1 proteins and how they alter cell cycles to keep the virus alive

  Aimed at understanding how HIV-1 proteins Vif and Vpr disrupt human cell division and help the virus persist, using advanced imaging to reveal new mechanisms.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11553199

• Metabolic Health and Lifestyle in Down Syndrome and Risk of Related Health Conditions

  A nationwide study aims to understand how metabolic health and daily habits affect health conditions like Alzheimer’s-related changes in people with Down syndrome.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11541246

• TULP3 and cilia function in human health

  This project studies how a key ciliary protein, TULP3, helps cells in human tissues communicate signals through primary cilia, with the goal of understanding diseases linked to ciliary dysfunction.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11540349

• Binaural hearing in kids with cochlear implants

  This project studies how age at deafness, auditory experience, and timing between implants affect hearing and thinking skills in children with bilateral cochlear implants and compares them to kids with normal hearing.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11538363

• Nonviral gene editing for inherited retinal blindness in LCA16

  A patient-focused program uses a CRISPR-based, nonviral approach to fix a specific genetic cause of pediatric blindness in the retina.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11537957

• Molecular Control of Protein Synthesis by the eEF2K Pathway

  Researchers are studying how a cellular switch called eEF2K controls protein production in cells, which could affect many diseases and brain cell function.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11537950

• Distributional Balancing for Causal Inference in Critical Care

  A study to develop new ways to draw reliable conclusions from complex critical care data by balancing patient characteristics across treatments.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11536503

• Linking Genetic Variants to Real-Life Health Effects with Smart AI

  A new AI-powered approach will predict how genetic differences affect health across multiple levels to help doctors understand diseases and tailor care.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11534375

• Regulating brain activity to help retinal cell replacement work

  This grant studies whether adjusting neural activity in the eye can help transplanted retinal cells connect with existing vision pathways to protect or restore sight in glaucoma patients.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11531377

• Revealing Proteoforms: The Driving Molecules Behind How Cells Work

  A disease-relevant project that aims to map the detailed protein forms and modifications in cells to better understand how HIV-related biology functions.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11529073

• Expanding Vet-LIRN AMR Surveillance with Phenotypic Testing and Genome Sequencing

  A One Health effort to better track antibiotic-resistant bacteria in animals and foods by combining lab tests and whole-genome sequencing.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11528938

• Rapid Response PCR Surge Framework for Emerging Foodborne and Zoonotic Pathogens

  A Wisconsin lab-led effort to create a rapid, scalable PCR testing framework to handle sudden outbreaks of foodborne and animal-to-human pathogens.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11528687

• How Metabolism Influences Persister Cells in Mammal Tumors

  This grant explores how metabolic changes in tumor cells help a small group of drug-tolerant persister cells survive treatment.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11524306

• National Translational Research Facility for Neutron Capture Therapy (NCT) at UW–Madison

  A national facility is being built at UW–Madison to advance neutron capture therapy for cancer, bringing together chemistry, imaging, and neutron treatment under one roof.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11523265

• Preventing and improving asthma care for children in urban communities

  This program will try several approaches — from giving helpful bacteria to babies to allergy immunotherapy and advanced airway testing — to prevent and better treat asthma in children who live in cities.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11521837

• Waisman Center IDD Research Center: advancing autism and ADHD research

  A large NIH grant supports a center that brings many experts together to study autism, ADHD, and related intellectual/developmental disabilities in children and families.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11519504

• Nociceptive nerve signals could rejuvenate aging blood stem cells

  A small grant is testing whether activating pain-sensing nerves in bone marrow with a molecule called CGRP can reverse aging changes in blood-forming stem cells.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11518986

• Healthy Brain and Child Development study across 27 sites

  This project studies how genes and early-life environments affect brain development in thousands of babies and young children.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11518983

• Midwest Center of Excellence for Vector-Borne Diseases (MCE-VBD)

  A regional effort to reduce infections from mosquitoes and ticks by improving prevention, control methods, and public education in the Midwest.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11509990

• Artificial Intelligence for Better Breast Cancer Screening

  A patient-friendly AI-based approach is being developed to improve the accuracy of breast cancer screening with 3D mammography.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11505239

• Collaborative modeling to improve breast cancer outcomes with AI support

  A national project uses computer models and AI tools to improve how we prevent, screen, and treat breast cancer for people at high risk or after diagnosis.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11494237

• How the brain protein FMRP shapes mitochondria and metabolism during human brain growth

  This project looks at how a protein called FMRP controls the brain's energy systems as the human brain develops, to help us better understand autism.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11493842

• Why dementia and sudden confusion (delirium) often happen together

  This project looks at brain electrical signals and chemical changes to find why people with dementia sometimes develop sudden confusion called delirium.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11480981

• Generational overlap and family resources across generations

  Aging, families, and economic status shape how grandparents, parents, and kids share time and resources across two countries.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11474399

• PLK4 as a potential drug target in melanoma

  Researchers are exploring whether blocking PLK4 could be a new way to treat melanoma and how PLK4 works with other melanoma-driving pathways.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11473224

• Understanding the enzyme that removes sugar tags from proteins (O-GlcNAcase)

  This research will look at how the O-GlcNAcase enzyme removes sugar tags from proteins and how that affects conditions like cancer and neurodegeneration.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11470306

• Video and text messages to reduce PTSD and opioid problems after sexual assault

  This project offers a short video in the emergency department plus follow-up text messages to help recent sexual assault survivors limit PTSD symptoms and prevent opioid misuse.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11466249

• Metabolic tuning in the eye to protect vision in aging and disease

  This grant supports research to understand how the retinal pigment epithelium keeps the eye’s cells energized and healthy, aiming to slow age-related eye degeneration.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11465710

• Asthma as a clue: how systemic inflammation may lead to Alzheimer’s disease

  A study explores whether chronic inflammation from asthma helps drive Alzheimer’s-like brain changes and whether targeting these pathways could reduce dementia risk.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11463250

• Axon-guidance genes and ALS/FTD: how neuron paths go wrong

  A short-term NIH grant will explore how axon guidance genes contribute to ALS and frontotemporal dementia in people and neuronal cells.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11458497

Quick answers

How many clinical trials run by University of Wisconsin-Madison are recruiting right now?

141, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (141 trials), Argentina (1 trial), Australia (1 trial), Germany (1 trial), India (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 17, Phase 1: 13, Phase 4: 5, Phase 3: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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