Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Understanding how the brain controls speech in healthy individuals

Official title: Behavioral and Neural Measures of Speech Motor Control

Run by University of Wisconsin, Madison · NCT06233513 · Data updated 2026-11-12

This study is trying to understand how healthy people control their speech by looking at how they adapt their speaking when they hear changes in their own voice.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment117 (estimated)
SponsorUniversity of Wisconsin, Madison
Academic / other
Locations1 site (Madison, Wisconsin)
StatusRecruiting
StartedFebruary 15, 2024
Main results expectedNovember 2026
Study endsNovember 2026
Registry record updatedOctober 26, 2026
Trial IDNCT06233513 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are English-speaking adults with normal hearing and speech, and no history of neurological conditions.

Probably not a fit

Patients with neurological disorders, hearing impairments, or those who are non-English speakers may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research aims to explore the cognitive, perceptual, and motor processes involved in speech control by studying healthy speakers. The study will enroll 329 participants over five years and consists of eight experiments focusing on how speech motor control is executed, maintained, and adapted under altered auditory feedback conditions. Participants will engage in various speaking tasks to assess how they perceive and adapt their speech sounds. The findings could provide insights into the mechanisms of speech perception and production.

Why it matters

Potential benefit: If successful, this research could enhance speech rehabilitation techniques for individuals with speech disorders.

How similar studies have gone: Other studies have shown promise in understanding speech motor control, but this specific approach to sensorimotor adaptation is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* English-speaking adults
* normal hearing and speech
* no history of stroke or neurological conditions

Exclusion Criteria:

* Native language other than English
* Any neurological disorders other than the disorder of interest
* Any history of hearing disorders
* Uncorrected vision problems that prevent participants from seeing visually-presented stimuli
* Significant cognitive impairments that prevent participants from carrying out the task or from giving informed consent
* Vulnerable populations (minors and prisoners)

Where it's running

  • University of Wisconsin
    Madison, Wisconsin, United States
    Recruiting

Study contacts

  • Principal investigator: Carrie Niziolek, PhD — University of Wisconsin, Madison
  • Study coordinator: Carrie Niziolek, PhD
  • Email: cniziolek@wisc.edu
  • Phone: 608-890-0192

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.