Ultrasound imaging to assess lower urinary tract symptoms

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research aims to develop a cost-effective ultrasound-based evaluation for voiding in patients with lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH). Participants will undergo a series of non-invasive imaging techniques, including MRI and ultrasound, to gather data on voiding flow rates and bladder pressures. The study will compare metrics obtained from ultrasound with those from established methods to validate the new approach. A total of 80 participants will be enrolled, including men with BPH/LUTS and age-matched healthy controls.

Why it matters

Who can join: the full rules

Inclusion Criteria: Patients with BPH/LUTS

* Age 18-80 years old
* Diagnosed with BPH/LUTS with or without obstruction

Exclusion Criteria:

* Patients with contraindication to MRI and/or GBCA contrast agent. Diabetic subjects will not receive contrast.
* History of overt neurologic disease other than diabetic neuropathy, urinary tract infection within the last 4 weeks or recent history of urinary retention (within the last 4 weeks).

Inclusion Criteria: Healthy Volunteers

\- Age 18-80 years old not experiencing any symptoms consistent with LUTS

Exclusion Criteria:

* Patients with contraindication to MRI and/or GBCA contrast agent.
* Currently taking medications with known effects on the bladder, overt neurologic disease other than diabetic neuropathy, urinary tract infection within the last 4 weeks or urinary retention symptoms.

Where it's running

• University of Wisconsin
  Madison, Wisconsin, United States Recruiting

Study contacts

• Principal investigator: Alejandro Roldan-Alzate, PhD — UW Department of Mechanical Engineering and Radiology
• Study coordinator: Radiology Studies
• Email: Radstudy@uwhealth.org
• Phone: 608-282-8349

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.