Ultrasound imaging to assess lower urinary tract symptoms
Ultrasound Imaging for the Assessment of Lower Urinary Tract Symptoms
University of Wisconsin, Madison · NCT06323109
This study is testing a new, cost-effective ultrasound method to see how well it can measure bladder function in men with lower urinary tract symptoms and benign prostatic hyperplasia.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | Male |
| Sponsor | University of Wisconsin, Madison (other) |
| Locations | 1 site (Madison, Wisconsin) |
| Trial ID | NCT06323109 on ClinicalTrials.gov |
What this trial studies
This research aims to develop a cost-effective ultrasound-based evaluation for voiding in patients with lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH). Participants will undergo a series of non-invasive imaging techniques, including MRI and ultrasound, to gather data on voiding flow rates and bladder pressures. The study will compare metrics obtained from ultrasound with those from established methods to validate the new approach. A total of 80 participants will be enrolled, including men with BPH/LUTS and age-matched healthy controls.
Who should consider this trial
Good fit: Ideal candidates include men aged 18-80 diagnosed with BPH/LUTS.
Not a fit: Patients with contraindications to MRI or those with recent urinary tract infections may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more accessible and cost-effective method for evaluating urinary symptoms in patients.
How similar studies have performed: Preliminary studies have shown promising results with similar imaging approaches, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients with BPH/LUTS * Age 18-80 years old * Diagnosed with BPH/LUTS with or without obstruction Exclusion Criteria: * Patients with contraindication to MRI and/or GBCA contrast agent. Diabetic subjects will not receive contrast. * History of overt neurologic disease other than diabetic neuropathy, urinary tract infection within the last 4 weeks or recent history of urinary retention (within the last 4 weeks). Inclusion Criteria: Healthy Volunteers \- Age 18-80 years old not experiencing any symptoms consistent with LUTS Exclusion Criteria: * Patients with contraindication to MRI and/or GBCA contrast agent. * Currently taking medications with known effects on the bladder, overt neurologic disease other than diabetic neuropathy, urinary tract infection within the last 4 weeks or urinary retention symptoms.
Where this trial is running
Madison, Wisconsin
- University of Wisconsin — Madison, Wisconsin, United States (RECRUITING)
Study contacts
- Principal investigator: Alejandro Roldan-Alzate, PhD — UW Department of Mechanical Engineering and Radiology
- Study coordinator: Radiology Studies
- Email: Radstudy@uwhealth.org
- Phone: 608-282-8349
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Lower Urinary Tract Symptoms, BPH