Mobile app for alcohol cessation in liver disease patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of the CHESS Health Connections smartphone application in helping patients with alcohol-associated liver disease (ALD) achieve alcohol cessation. Conducted at two major medical centers in Michigan and Wisconsin, the trial will enroll 298 participants who will be monitored for up to 6 months. The study compares the outcomes of patients using the app alongside usual care to those receiving only usual care, aiming to improve abstinence rates and liver function. Additionally, qualitative interviews will assess the implementation of the app within clinical settings.

Why it matters

Who can join: the full rules

Inclusion Criteria (Aim 1):

* Diagnosis of ALD (any stage)
* Alcoholic liver disease (ALD) encompasses a spectrum of hepatic injuries caused by long-term alcohol abuse. For this study, participants will have a diagnosis of ALD or evidence of the combination of liver disease and alcohol misuse in electronic health record.
* Alcohol use within the last 6 months
* Receiving care at UW or Henry Ford Health + MSU

  * Either the general hepatology clinic or the multidisciplinary ALD clinic
* Able to read and write proficiently in English
* Willing and able to use a smartphone app

Exclusion Criteria:

* Actively listed for liver transplant or history of liver transplant before being enrolled in the study. Participants added to a liver transplant list after being enrolled in the study will be allowed to continue their participation
* In hospice care
* Has severe cognitive impairment (as described in electronic health record including dementia, delirium, and/or unable to maintain cognitive alertness during screening--as determined by study staff.)

Where it's running

• Henry Ford + Michigan State University Health Center
  Lansing, Michigan, United States Recruiting
• UW General Hepatology Clinic
  Madison, Wisconsin, United States Recruiting
• UW Multidisciplinary ALD Clinic
  Madison, Wisconsin, United States Recruiting

Study contacts

• Principal investigator: Andrew Quanbeck, PhD — University of Wisconsin, Madison
• Study coordinator: Jared P McDonald, MBA
• Email: jared.mcdonald@fammed.wisc.edu
• Phone: 608-263-4022

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.