Registry for people interested in CADASIL research
Official title: Research Registry for Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL)
Run by University of Wisconsin, Madison · NCT05567744 · Data updated 2026-11-12
This study is creating a registry of people with CADASIL or their family members to help researchers find candidates for future studies on this condition.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 90 Years |
| Sex | All |
| Enrollment | 2500 (estimated) |
| Sponsor | University of Wisconsin, Madison Academic / other |
| Locations | 1 site (Madison, Wisconsin) |
| Status | Recruiting |
| Started | June 3, 2022 |
| Main results expected | October 2027 |
| Study ends | October 2027 |
| Registry record updated | October 23, 2026 |
| Trial ID | NCT05567744 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this registry are individuals aged 18 and older who have a family member with CADASIL or are at risk of developing the condition themselves.
✕Probably not a fit
Patients who are under 18 years of age will not benefit from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This registry aims to gather individuals who are either affected by or have a family member with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL). Participants will be added to a list that researchers can use to identify potential candidates for future studies related to CADASIL. The registry will collect uniform data to evaluate outcomes for this specific condition and will remain active until participants choose to withdraw. This initiative is led by Dr. Jane Paulsen and her research team at the University of Wisconsin.
Why it matters
Potential benefit: If successful, this registry could facilitate more targeted research and clinical trials for CADASIL, potentially leading to better treatment options.
How similar studies have gone: While this registry approach is common, it is essential for advancing CADASIL research, and similar registries have successfully facilitated research in other rare conditions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years of age or older * have a loved one or a family member with CADASIL, or are at-risk for CADASIL themselves Exclusion Criteria: * Under 18 years of age
Where it's running
-
University of Wisconsin
Madison, Wisconsin, United States Recruiting
Study contacts
- Principal investigator: Jane Paulsen, PhD — University of Wisconsin, Madison
- Study coordinator: CADASIL Consortium
- Email: info@cadasil-consortium.org
- Phone: 833-795-3016
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.