Registry for people interested in CADASIL research

Research Registry for Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL)

Observational University of Wisconsin, Madison · NCT05567744

This study is creating a registry of people with CADASIL or their family members to help researchers find candidates for future studies on this condition.

Quick facts

Study typeObservational
Enrollment2500 (estimated)
Ages18 Years to 90 Years
SexAll
SponsorUniversity of Wisconsin, Madison Academic / other
Locations1 site (Madison, Wisconsin)
Trial IDNCT05567744 on ClinicalTrials.gov

What this trial studies

This registry aims to gather individuals who are either affected by or have a family member with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL). Participants will be added to a list that researchers can use to identify potential candidates for future studies related to CADASIL. The registry will collect uniform data to evaluate outcomes for this specific condition and will remain active until participants choose to withdraw. This initiative is led by Dr. Jane Paulsen and her research team at the University of Wisconsin.

Who should consider this trial

Good fit: Ideal candidates for this registry are individuals aged 18 and older who have a family member with CADASIL or are at risk of developing the condition themselves.

Not a fit: Patients who are under 18 years of age will not benefit from this registry.

Why it matters

Potential benefit: If successful, this registry could facilitate more targeted research and clinical trials for CADASIL, potentially leading to better treatment options.

How similar studies have performed: While this registry approach is common, it is essential for advancing CADASIL research, and similar registries have successfully facilitated research in other rare conditions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years of age or older
* have a loved one or a family member with CADASIL, or are at-risk for CADASIL themselves

Exclusion Criteria:

* Under 18 years of age

Where this trial is running

Madison, Wisconsin

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cerebral Autosomal Dominant Ateriopathy With Subcortical Infarcts and LeukoencephalopathyCADASIL
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.