NIH-funded research U01 cooperative agreement

Collaborative modeling to improve breast cancer outcomes with AI support

Official title: Collaborative Modeling to Identify Strategies to Improve US Breast Cancer Outcomes in an Era of Innovation

Funded at University of Wisconsin-Madison · NIH-11494237 · Data updated 2026-11-12

A national project uses computer models and AI tools to improve how we prevent, screen, and treat breast cancer for people at high risk or after diagnosis.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Wisconsin-Madison
NIH-funded
Lab location1 site (Madison, United States)
Project startSeptember 17, 2026
Project endAugust 31, 2031
Funding year2026
Award (this year)$1,839,480
NIH project number1U01CA319080-01
Project IDNIH-11494237 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates include individuals at high inherited risk or elevated risk of breast cancer, patients considering screening or treatment options, and breast cancer survivors.

Less likely to help

Patients not involved in screening, prevention, or treatment decision pathways or those outside the defined high-risk groups may see limited direct benefit.

What this research studies

This grant supports a collaborative effort at UW–Madison to translate cutting-edge AI and modeling into real-world breast cancer care. Researchers will combine existing models and new AI insights to forecast outcomes from different risk-reduction, screening, and treatment options and to guide clinical practice. The work focuses on two high-risk groups, long-term population impact of AI in screening, and how post-diagnosis exercise and therapies affect survival and quality of life. Results are intended to help clinicians and patients make better-informed decisions at multiple steps of the care pathway.

Why it matters

Potential benefit: If successful, the project could refine screening and treatment decisions, reducing breast cancer mortality and improving survivor well-being.

How similar studies have gone: The grant builds on CISNET’s established modeling framework with a track record of informing public health decisions; AI-enhanced analyses are an expanding area with promising early results.

Where this research is happening

  • University of Wisconsin-Madison
    Madison, United States
    Active

Researchers

  • Principal investigator: Trentham-Dietz, Amy — University of Wisconsin-Madison
  • Study coordinator: Trentham-Dietz, Amy

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.