Evaluating a Neurologic Assessment Scale for Pediatric Brain and Spine Tumors
Evaluation of the Neurologic Assessment in Pediatric Neuro-Oncology (pNANO)
This study is testing a new neurologic exam scale for kids with brain and spine tumors to see how consistently different doctors can use it to check their progress, including doing some assessments through telemedicine.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 75 (estimated) |
| Ages | 1 Year to 17 Years |
| Sex | All |
| Sponsor | University of Wisconsin, Madison Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Madison, Wisconsin) |
| Trial ID | NCT06981156 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the inter-observer variability of the pNANO scale, a neurologic exam scale designed for pediatric patients with brain and spinal cord tumors. During routine clinic visits, neurologic examinations will be conducted by multiple independent providers to ensure objective assessment of tumor response. Each provider will document their findings on the pNANO scale without communicating with one another, allowing for a blinded evaluation. The study will also explore the feasibility of conducting these assessments via telemedicine for a subset of participants.
Who should consider this trial
Good fit: Ideal candidates include pediatric patients aged 1 year and older with confirmed brain or spine tumors who are being seen in a pediatric clinic.
Not a fit: Patients without a confirmed diagnosis of a brain or spine tumor or those who cannot provide informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to a more standardized and objective method for assessing tumor response in pediatric patients, improving treatment monitoring.
How similar studies have performed: While the pNANO scale is a novel approach, similar studies assessing inter-observer variability in clinical evaluations have shown promise in improving assessment accuracy.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * greater than or equal to 1 year old * must be seen in the pediatric clinic * Radiographic or histologic confirmation of a brain or spine tumor at the time of initial diagnosis * Patient or parent/guardian must be able to understand the consent and be willing to sign a written informed consent document according to institutional guidelines. Exclusion Criteria: * none specified
Where this trial is running
Madison, Wisconsin
- American Family Children's Hospital — Madison, Wisconsin, United States (Recruiting)
Study contacts
- Principal investigator: Austin Stuckert, MD — UW School of Medicine and Public Health
- Study coordinator: Cancer Connect
- Email: clinicaltrials@cancer.wisc.edu
- Phone: 800-622-8922
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.