Comparing two imaging systems for inherited retinal disease
COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Inherited Retinal Disease
NA · University of Wisconsin, Madison · NCT06380075
This study is testing whether two new eye imaging systems can provide similar information as a standard system for people with inherited retinal diseases.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Wisconsin, Madison (other) |
| Locations | 1 site (Madison, Wisconsin) |
| Trial ID | NCT06380075 on ClinicalTrials.gov |
What this trial studies
This research aims to compare the effectiveness of two ultrawide field imaging systems, Clarus and Optos, against a gold standard imaging system for evaluating inherited retinal diseases (IRDs). Participants aged 18 and older with a clinical or genetic diagnosis of IRD will undergo pupillary dilation and have their eyes photographed using all three imaging systems. The study seeks to determine if similar results and information can be obtained from these cameras for monitoring IRDs.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 18 and older with a clinical or genetic diagnosis of inherited retinal disease.
Not a fit: Patients with advanced ocular conditions that may interfere with imaging quality or interpretation will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the accuracy and reliability of imaging techniques used for diagnosing and monitoring inherited retinal diseases.
How similar studies have performed: While this approach is comparative, similar studies have shown promise in improving imaging techniques for retinal diseases.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants 18 years and older with a clinical and/ or genetic diagnosis of IRD recruited either from the clinic and/or the Inherited Ocular Disease Registry to participate in this trial * Participants that are willing to participate as evidenced by signing the written informed consent Exclusion Criteria: * Presence of ocular conditions other than an IRD which may affect the quality of ocular imaging including but not limited to advanced cataracts, corneal disorders, nystagmus, vitreous hemorrhage, or poor dilation * Presence of ocular conditions other than an IRD which may affect interpretation of retinal imagining including but not limited to epiretinal membrane, choroidal neovascular membrane, or macular scarring * Patients with advanced IRDs who are unable to fixate for imaging * Patients unable to tolerate ocular imaging * Patients who do not wish to participate
Where this trial is running
Madison, Wisconsin
- Department of Ophthalmology and Visual Sciences — Madison, Wisconsin, United States (RECRUITING)
Study contacts
- Principal investigator: Kimberly Stepien, MD — University of Wisconsin, Madison
- Study coordinator: Angie Adler
- Email: amadler1@wisc.edu
- Phone: 608-265-7557
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Retinal Disease