The ENHANCE Project Toolkit

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a feasibility-focused pilot study enrolling 40 adults to test a mobile health toolkit for overdose prevention, including crisis hotlines, mailed supplies, and an adapted app for motivation and peer support. Participants receive a smartphone and unlimited data, plus monthly surveys and optional in-depth interviews to gauge feasibility, acceptability, and appropriateness of the intervention. The study will quantify preliminary effect sizes to inform future trials, without making strong claims about biomedical or behavioral outcomes. Data will be collected over up to 9 months to understand how the tools are used and perceived by people who use drugs and related populations.

Why it matters

Who can join: the full rules

Inclusion Criteria (Pilot Participant):

* Be at least 18 years old
* Be able to read and write in English
* Report drug use in the past 30 days, defined as

  * Any use of illicit stimulants, opioids, OR
  * Use of prescription opioids by a route other than "by mouth/swallowed"
* Additionally report recent drug use of at least twice in the past 7 days
* Express perceived unmet needs for harm reduction services

Inclusion Criteria (Peer Mentor Participant):

* Be at least 18 years old
* Be able to read and write in English
* Have served as a member of the existing Community Leadership Team.

Exclusion Criteria:

* Are under the age of 18
* Have impaired decision making capacity at the time of screening
* Do not have the ability to participate in screening and enrollment activities in any one of the following ways:

  * Traveling to their nearest participating Vivent Health health center
  * Coordinating a visit with the Vivent Health harm reduction mobile unit
  * Accessing and completing the online screening survey on a personal wifi/internet enabled device

Where it's running

• UW School of Medicine and Public Health
  Madison, Wisconsin, United States Recruiting

Study contacts

• Principal investigator: Rachel Gicquelais, PhD, MPH — UW School of Medicine and Public Health
• Study coordinator: Research Team
• Email: enhance@medicine.wisc.edu
• Phone: (608) 572-3514

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.