New quick MRI method for pediatric kidney disease
Official title: The Validity of the Quick Renal MRI in Pediatric Kidney Disease
Run by University of Wisconsin, Madison · NCT03959163 · Data updated 2026-11-12
This study is testing a new, faster MRI method for kids with kidney problems to see if it can better detect infections and damage without using radiation or injections.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 0 Years to 21 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | University of Wisconsin, Madison Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Madison, Wisconsin) |
| Status | Recruiting |
| Started | May 7, 2019 |
| Main results expected | January 2025 |
| Study ends | January 2025 |
| Registry record updated | April 3, 2024 |
| Trial ID | NCT03959163 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are children aged 0-21 years admitted for febrile urinary tract infections or diagnosed pyelonephritis.
✕Probably not a fit
Patients without evidence of pyuria or negative urine cultures, as well as those with contraindications to MRI, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates a new imaging technique called quick renal MRI, designed for children with congenital urinary tract anomalies who are at risk for kidney infections and scarring. The quick renal MRI aims to provide a rapid, injection-, sedation-, and radiation-free alternative to the current standard, the 99mTc-DMSA renal scan, which is time-consuming and involves radiation exposure. The study will compare the effectiveness of the quick renal MRI in detecting acute renal infections and scars against the DMSA scan. Participants will include children aged 0-21 years, with varying study durations depending on their enrollment aim.
Why it matters
Potential benefit: If successful, this new imaging method could significantly reduce the burden of testing for children with chronic renal disease by eliminating the need for sedation and radiation exposure.
How similar studies have gone: While this approach is innovative, it builds on existing imaging techniques, and similar studies have shown promise in improving pediatric imaging methods.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aim 1: * Patient is admitted to American Family Children's Hospital for a febrile UTI, suspected pyelonephritis, or diagnosed pyelonephritis * Undergoing clinical DMSA scan * Aim 2: * Undergoing DMSA scans as a part of their routine clinical care * History of more than one UTI in the past year Exclusion Criteria: * Aim 1: * No evidence of pyuria on their urine analysis * Negative urine culture * Not comfortable with having a Quick MRI performed * Both aims: * Contraindications to MRI
Where it's running
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American Family Children's Hospital
Madison, Wisconsin, United States Recruiting
Study contacts
- Principal investigator: Shannon Cannon, MD — University of Wisconsin, Madison
- Study coordinator: Shannon Cannon, MD
- Email: cannon@urology.wisc.edu
- Phone: (608) 265-8574
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.