Clinical trial Recruiting at 1 site Interventional Ages 0 to 21

New quick MRI method for pediatric kidney disease

Official title: The Validity of the Quick Renal MRI in Pediatric Kidney Disease

Run by University of Wisconsin, Madison · NCT03959163 · Data updated 2026-11-12

This study is testing a new, faster MRI method for kids with kidney problems to see if it can better detect infections and damage without using radiation or injections.

Quick facts

Study typeInterventional
Ages0 Years to 21 Years
SexAll
Enrollment100 (estimated)
SponsorUniversity of Wisconsin, Madison
Academic / other
Drugs / interventionsradiation
Locations1 site (Madison, Wisconsin)
StatusRecruiting
StartedMay 7, 2019
Main results expectedJanuary 2025
Study endsJanuary 2025
Registry record updatedApril 3, 2024
Trial IDNCT03959163 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are children aged 0-21 years admitted for febrile urinary tract infections or diagnosed pyelonephritis.

Probably not a fit

Patients without evidence of pyuria or negative urine cultures, as well as those with contraindications to MRI, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates a new imaging technique called quick renal MRI, designed for children with congenital urinary tract anomalies who are at risk for kidney infections and scarring. The quick renal MRI aims to provide a rapid, injection-, sedation-, and radiation-free alternative to the current standard, the 99mTc-DMSA renal scan, which is time-consuming and involves radiation exposure. The study will compare the effectiveness of the quick renal MRI in detecting acute renal infections and scars against the DMSA scan. Participants will include children aged 0-21 years, with varying study durations depending on their enrollment aim.

Why it matters

Potential benefit: If successful, this new imaging method could significantly reduce the burden of testing for children with chronic renal disease by eliminating the need for sedation and radiation exposure.

How similar studies have gone: While this approach is innovative, it builds on existing imaging techniques, and similar studies have shown promise in improving pediatric imaging methods.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aim 1:

  * Patient is admitted to American Family Children's Hospital for a febrile UTI, suspected pyelonephritis, or diagnosed pyelonephritis
  * Undergoing clinical DMSA scan
* Aim 2:

  * Undergoing DMSA scans as a part of their routine clinical care
  * History of more than one UTI in the past year

Exclusion Criteria:

* Aim 1:

  * No evidence of pyuria on their urine analysis
  * Negative urine culture
  * Not comfortable with having a Quick MRI performed
* Both aims:

  * Contraindications to MRI

Where it's running

  • American Family Children's Hospital
    Madison, Wisconsin, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.