Condition

Neoplasms clinical trials and research

• 102Clinical trials
• 52NIH research projects
• 1New in 30 days
• 33Countries

Newest Neoplasms clinical trials

All recruiting trials (102)

• HR20013 for preventing nausea and vomiting in cancer patients receiving chemotherapy

  This real-world study tests whether HR20013 helps prevent nausea and vomiting in adults with cancer who are getting chemotherapy.

  Recruiting Sun Yat-sen University · Guangzhou, Guangdong · NCT07874308

• Methylscape test in body fluids for multi-cancer detection in Colombia

  A simple blood, urine, or saliva test called Methylscape is being tested to see if it can detect multiple cancers and identify where the signal is coming from, using people with cancer and healthy volunteers in Colombia.

  Recruiting Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo · Bogotá, Bogota D.C. · NCT07741435

• Ready for Safe Cancer Treatment (RESET): A comprehensive perioperative program for surgical patients

  The RESET program tests a structured, multidisciplinary perioperative plan to improve safety and recovery for adults having planned cancer surgery and older adults having planned non cancer-related surgery.

  Recruiting at 2 sites Regional Specialist Hospital in Wroclaw · Wroclaw, Lower Silesian Voivodeship and 1 other locations · NCT07727876

• How environment and biology together predict health, aging, and death

  Researchers are following adults to see how living conditions and biology together relate to aging and life expectancy, by linking personal health data with environmental and social information over time.

  Recruiting Longevity Metrics, Inc. · Boulder, Colorado · NCT07646782

• Metastatic liver cancer patient registry from multiple Chinese centers

  This is a registry that collects real-world data on adults with liver metastases to understand patterns and prognosis and to support future research.

  Recruiting at 2 sites Anhui Provincial Hospital · Bengbu, Anhui and 2 other locations · NCT07602504

• TriAdeno and N-803 vaccine in early prostate cancer on active surveillance

  A vaccine combo called TriAdeno plus the N-803 drug is being tested to see if it can help slow or stop growth in men with early-stage, low- to intermediate-risk prostate cancer who are being watched rather than treated right away.

  Recruiting Phase 2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT07574541

• 100-Year Human Aging and Longevity Tracking Program

  This project will follow adults over their lifetimes to see if repeated health tests can predict lifespan, causes of death, serious disease, and loss of function.

  Recruiting Longevity Metrics, Inc. · Boulder, Colorado · NCT07563777

• Predicting who will need ICU care after cancer surgery

  This study will test common risk scores to see if they can predict which adult cancer surgery patients will need ICU care after their operation.

  Recruiting Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital · Ankara · NCT07542925

• JNJ-1761981 in solid tumors

  A early-phase study tests how safe and tolerable a single intratumor injection of JNJ-1761981 is, and how to best dose it, in adults with solid tumors that have progressed after standard treatment.

  Recruiting at 4 sites Phase 1 Johnson & Johnson Enterprise Innovation Inc. · Jacksonville, Florida and 3 other locations · NCT07525141

• Real-world use of LC-OCT to help diagnose basal cell carcinoma

  This study tests how well LC-OCT works in everyday dermatology practice to help diagnose basal cell carcinoma without always needing a biopsy.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT07501780

• LRK-4189: a first look at safety and early effectiveness in solid tumors

  This study tests LRK-4189, alone or with chemotherapy, to see if it is safe and tolerable for adults with advanced solid tumors, including colorectal cancer.

  Recruiting at 3 sites Phase 1/2 Larkspur Biosciences, INC. · Nice and 2 other locations · NCT07498725

• SLC-3010 plus axitinib versus axitinib alone for second-line treatment of advanced clear cell kidney cancer

  This trial tests whether adding SLC-3010 to axitinib works better than axitinib alone for adults with locally advanced or metastatic clear cell kidney cancer who need second-line treatment.

  Recruiting Phase 2 Yonsei University · Seoul · NCT07469683

• GSK5533524 alone or with other treatments for adults with advanced solid tumors

  This trial tests whether the new drug GSK5533524, given alone or with other therapies, is safe, tolerable, and can shrink or slow advanced solid tumors in adults who have no standard treatment options left.

  Recruiting at 20 sites Phase 1 GlaxoSmithKline · Philadelphia, Pennsylvania and 19 other locations · NCT07438782

• JV-394 CAR T therapy for relapsed or refractory CD94-positive T/NK-cell cancers

  This trial will test whether using a patient’s own modified immune cells (JV-394 CAR T) is safe and find the best dose for adults with relapsed or refractory CD94-positive T/NK-cell lymphoma.

  Recruiting Phase 1 M.D. Anderson Cancer Center · Houston, Texas · NCT07382817

• IMMUNO-FIT: How immunotherapy affects fitness and quality of life in adults with solid cancers

  We will see if starting immunotherapy changes physical fitness, quality of life, and how well adults with solid cancers tolerate treatment.

  Recruiting University Hospital Southampton NHS Foundation Trust · Southampton, Hampshire · NCT07354971

• GSK5764227 given with standard therapies for advanced solid tumors

  This trial will test whether GSK5764227, a drug that delivers a toxin directly to cancer cells, can be safely given alongside standard treatments in adults with advanced solid tumors such as metastatic colorectal cancer or metastatic castration-resistant prostate cancer.

  Recruiting at 22 sites Phase 1 GlaxoSmithKline · Reunion, Florida and 21 other locations · NCT07277270

• Nenocorilant plus nivolumab for advanced solid tumors

  This trial tests whether adding the oral drug nenocorilant to nivolumab is safe and can identify the best dose for people with advanced solid tumors.

  Recruiting at 5 sites Phase 1/2 Corcept Therapeutics · Los Angeles, California and 4 other locations · NCT07276373

• PET imaging with [18F]LY4214835 in adults with cancer and healthy volunteers

  This research will test a single IV injection of [18F]LY4214835 in adults with cancer and in healthy volunteers to see if it is safe and well tolerated.

  Recruiting at 2 sites Phase 1 Eli Lilly and Company · New Haven, Connecticut and 5 other locations · NCT07258836

• IL-5 CAR-T therapy for refractory or relapsed eosinophilic leukemia

  We will test whether IL-5 CAR-T cells can help adults with CD125-positive refractory or relapsed eosinophilic leukemia.

  Recruiting Phase 1 Zhejiang University · Hangzhou, Zhejiang · NCT07257640

• Self‑manual lymph drainage for head and neck lymphedema

  This trial will test whether different intensities of self‑applied manual lymph drainage help people with head and neck lymphedema after radiotherapy for oropharyngeal cancer.

  Recruiting Lund University · Lund, Skåne County · NCT07215169

• GSK5460025 alone or with other anti-cancer drugs for advanced solid tumors

  This trial will test whether the experimental drug GSK5460025, alone or combined with other cancer medicines, can shrink tumors and be safe for people with advanced colorectal or other solid tumors that are dMMR/MSI-H or have unknown MMR/MSI status.

  Recruiting at 27 sites Phase 1/2 GlaxoSmithKline · Aurora, Colorado and 26 other locations · NCT07213609

• Interactive online course to improve cancer patients' digital health skills

  This project will test whether an interactive online course helps people with cancer improve their ability to find and understand reliable health information online compared with reading a PDF or receiving no material.

  Recruiting Universitätsklinikum Hamburg-Eppendorf · Hamburg, Free and Hanseatic City of Hamburg · NCT07200453

• Machine-learning prediction of heart damage from anthracycline or HER2 cancer therapies

  We will see if a machine-learning score can predict which adults starting anthracycline or HER2-targeted cancer therapies will develop heart damage within one year.

  Recruiting University Hospital, Caen · Caen · NCT07191730

• LY3537021 for preventing chemo-related nausea and vomiting in adults

  This trial will test whether adding LY3537021 to standard anti-nausea care helps prevent nausea and vomiting in adults starting AC or high-dose cisplatin chemotherapy.

  Recruiting at 58 sites Phase 2 Eli Lilly and Company · Greenbrae, California and 66 other locations · NCT07169851

• High-sensitivity blood test to detect and monitor multiple cancers

  This study will test a high-sensitivity blood test that looks for tumor DNA to detect and follow several common cancers in adults with those cancers or people having routine health screenings.

  Recruiting Yonsei University · Seoul · NCT07035587

• Nurse-led program to help adults with cancer stay active during outpatient treatment

  This project will try a nurse-led program to help adults with cancer stay more physically active while they receive outpatient treatments.

  Recruiting St.Gallen University of Applied Sciences · Münsterlingen · NCT06999616

• Early intervention strategies for lung cancer detection

  This study is testing if using low-dose CT scans in community health centers can help find lung cancer earlier in people aged 40-75 who don't have a history of the disease.

  Recruiting The First Affiliated Hospital of Guangzhou Medical University · Guangzhou, Guangdong · NCT06988943

• Combining Dabrafenib with FOLFOX and Cetuximab/Panitumumab for Metastatic Colorectal Cancer

  This study is testing if a new combination of chemotherapy and targeted treatments can help people with metastatic colorectal cancer that has a specific mutation feel better and live longer.

  Recruiting Phase 2 Blokhin's Russian Cancer Research Center · Moscow · NCT06978400

• Evaluating CS231295 for advanced solid tumors

  This study is testing a new drug called CS231295 to see if it is safe and effective for people with advanced solid tumors that haven't responded to other treatments.

  Recruiting Phase 1 Chipscreen Biosciences, Ltd. · Beijing, Beijing Municipality and 1 other locations · NCT06902350

• Anti-mesothelin TNhYP218 CAR T cell therapy for mesothelin-expressing solid tumors

  This treatment will test whether a person's own engineered CAR T cells that target mesothelin can help adults with mesothelin-expressing solid tumors, including mesothelioma, that have returned or spread after standard therapy.

  Recruiting Phase 1 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT06885697

• Advanced cancer diagnosis using multi-omic profiling

  This study is testing a new way to improve cancer diagnosis by using a mix of biological samples and medical images to help doctors choose the best treatments for patients in Italy.

  Recruiting National Cancer Institute, Naples · Naples · NCT06884878

• Evaluating a new treatment for advanced solid tumors with RAS mutations

  This study is testing a new treatment called RO7673396 to see if it is safe and effective for people with advanced solid tumors that have RAS mutations.

  Recruiting at 25 sites Phase 1 Hoffmann-La Roche · Duarte, California and 24 other locations · NCT06884618

• How the immune system affects a person's sensitivity to radiotherapy.

  This project tests whether differences in patients' immune cells are linked to who does or does not develop severe side effects after radiotherapy.

  Recruiting Assistance Publique - Hôpitaux de Paris · Créteil, Île-de-France Region · NCT06826066

• Evaluating VB15010 Tablets for Advanced Solid Tumors

  This study is testing a new tablet called VB15010 to see if it can help people with advanced solid tumors and specific genetic mutations feel better and fight their cancer.

  Recruiting Phase 1/2 Zhejiang Yangli Pharmaceutical Technology Co., Ltd. · Jinan, Shandong · NCT06819215

• Comparing Ruxolitinib with Steroids for Chronic Graft-versus-Host Disease Treatment

  This study is testing if a new treatment combining Ruxolitinib with steroids can help people with moderate to severe chronic graft-versus-host disease feel better compared to just using steroids alone.

  Recruiting Phase 2 Seoul St. Mary's Hospital · Seoul, Banpo-daero/Seocho-gu · NCT06756061

• E-CANE: national remote therapeutic education workshops for adolescents and young adults with cancer

  This program will try remote therapeutic education workshops to help adolescents and young adults in France living with cancer learn self-care skills and cope with treatment.

  Recruiting Centre Hospitalier Universitaire de Nice · Nice, Alpes Maritimes · NCT06748820

• Examining drug interactions in older adults living with HIV

  This study looks at how different medications interact in older adults with HIV to see if we can improve their treatment plans.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna · NCT06717581

• Using 18F-Fluciclovine PET/CT to Predict Outcomes of Prostate Cancer Therapy

  This study is testing if special imaging can help predict how well a new prostate cancer treatment works for patients with advanced disease.

  Recruiting Phase 4 VA Greater Los Angeles Healthcare System · Los Angeles, California · NCT06706921

• Evaluating AST-201 for GPC3-positive advanced solid tumors

  This study is testing a new treatment called AST-201 to see if it can help people with advanced solid tumors that have a specific marker called GPC3.

  Recruiting at 4 sites Phase 1 Aptamer Sciences, Inc. · Goyang-si, Gyeonggi-do and 3 other locations · NCT06687941

• CD70-targeted immunoPET Imaging of Kidney Cancer

  This study is testing a new imaging technique that uses a special marker to help doctors see kidney cancer more clearly.

  Recruiting Phase 2 RenJi Hospital · Shanghai, Shanghai Municipality · NCT06680089

• Using vorolanib for treating advanced kidney cancer

  This study is testing if the drug vorolanib can help people with advanced kidney cancer live longer when used as a second treatment option.

  Recruiting Jinling Hospital, China · Nanjing, Jiangsu · NCT06676527

• Screening methods for high-risk anal cancer patients

  This study is testing new ways to screen for early signs of anal cancer in high-risk people, especially those living with HIV, to help improve their health outcomes.

  Recruiting at 4 sites Emory University · Miami, Florida and 3 other locations · NCT06628570

• Exploring awareness and knowledge of social egg freezing in Hong Kong

  This study is trying to find out how much young adults and doctors in Hong Kong know about social egg freezing and if they accept it, to help create better education and support for fertility preservation.

  Recruiting Chinese University of Hong Kong · Hong Kong · NCT06581666

• Testing GSK5764227 in patients with advanced solid tumors

  This study is testing a new cancer drug called GSK5764227 to see if it is safe and effective for people with advanced solid tumors, both on its own and with other treatments.

  Recruiting at 66 sites Phase 1 GlaxoSmithKline · Stanford, California and 66 other locations · NCT06551142

• Freezing and transplanting ovarian tissue for young female cancer patients

  This study is testing if freezing and later transplanting ovarian tissue can help young female cancer patients preserve their ability to have children after treatment.

  Recruiting Chinese University of Hong Kong · Hong Kong · NCT06505057

• Evaluating Bevacizumab with Focused Ultrasound for Recurrent Glioblastoma

  This study is testing if adding focused ultrasound to the standard treatment of Bevacizumab can help people with recurrent glioblastoma feel better and live longer.

  Recruiting at 2 sites Phase 3 NaviFUS Corporation · Taipei and 1 other locations · NCT06496971

• Effects of nutrient timing on cancer-related fatigue

  This study is testing if eating all meals within a 10-hour window can help cancer survivors with blood cancers feel less tired and improve their quality of life.

  Recruiting Phase 2 University of Maryland, Baltimore · Baltimore, Maryland · NCT06482515

• Evaluating GSK5733584 for advanced solid tumors

  This study is testing a new injectable treatment called GSK5733584 to see if it's safe and how it works for people with advanced solid tumors that haven't responded to other treatments.

  Recruiting at 64 sites Phase 1 GlaxoSmithKline · Birmingham, Alabama and 64 other locations · NCT06431594

• Health coaching program for lung and esophageal cancer patients before surgery

  This study tests a health coaching program to see if it can help lung and esophageal cancer patients improve their health before surgery.

  Recruiting Nova Scotia Health Authority · Halifax, Nova Scotia · NCT06354959

• Evaluating a new treatment for advanced solid tumors

  This study is testing a new virus injection to see if it can help people with advanced solid tumors that haven't improved with standard treatments.

  Recruiting Early Phase 1 Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Beijing · NCT06346041

• Testing JNJ-87704916 for advanced solid tumors

  This study is testing a new treatment called JNJ-87704916, alone and with another drug, to see if it can help people with advanced solid tumors feel better and improve their health.

  Recruiting at 9 sites Phase 1 Johnson & Johnson Enterprise Innovation Inc. · New York, New York and 9 other locations · NCT06311578

• Imaging tumors with a special radiodrug targeting HER2 protein

  This study is testing a new imaging drug that targets the HER2 protein to see if it can help doctors better identify and understand different cancers, especially breast cancer.

  Recruiting Peking University First Hospital · Beijing, Beijing Municipality · NCT06289517

• Evaluating a new CAR-T cell therapy for relapsed/refractory multiple myeloma

  This study is testing a new CAR-T cell therapy called OriCAR-017 to see if it can help people with relapsed or refractory multiple myeloma feel better and improve their treatment outcomes.

  Recruiting Phase 1 OriCell Therapeutics Co., Ltd. · Atlanta, Georgia · NCT06271252

• Personalized live-remote exercise training for cancer survivors

  This study tests whether a personalized online exercise program can help cancer survivors feel better and improve their fitness while dealing with fatigue, anxiety, and depression.

  Recruiting UMC Utrecht · Utrecht · NCT06270628

• Exploring the unmet needs of cancer survivors in Reggio Emilia

  This study is trying to find out what cancer survivors need most after finishing their treatment to help improve their care and quality of life.

  Recruiting University of Modena and Reggio Emilia · Reggio Emilia, Reggio Emilia · NCT06236373

• Testing JNJ-87890387 for advanced solid tumors

  This study is testing a new drug called JNJ-87890387 to see how safe it is and what the right dose is for people with advanced solid tumors like kidney cancer, ovarian cancer, and lung cancer.

  Recruiting at 6 sites Phase 1 Janssen Research & Development, LLC · Grand Rapids, Michigan and 5 other locations · NCT06178614

• Treatment of CALR-Mutated Myeloproliferative Neoplasms with JNJ-88549968

  This study is testing a new treatment called JNJ-88549968 to see if it is safe and effective for people with CALR-mutated myeloproliferative neoplasms.

  Recruiting at 45 sites Phase 1 Janssen Research & Development, LLC · Goodyear, Arizona and 45 other locations · NCT06150157

• Biobank for pancreatic adenocarcinoma research

  This study is collecting samples and information from people with pancreatic cancer to help find better ways to diagnose and treat the disease.

  Recruiting University Hospital, Toulouse · Béthune and 7 other locations · NCT06128343

• Biennial contrast-enhanced mammography for women with a history of breast cancer

  This study is testing if using a special type of mammogram every two years along with yearly 3D breast scans can help women with a history of breast cancer find any new cancers more effectively than just the yearly scans alone.

  Recruiting at 6 sites University of Pittsburgh · Bethel Park, Pennsylvania and 5 other locations · NCT06105749

• Proactive palliative care model for advanced cancer patients

  This study tests a new telehealth support program for advanced cancer patients and their caregivers to see if it helps them feel better and manage their care more effectively compared to regular treatment.

  Recruiting National Cancer Centre, Singapore · Singapore · NCT06044441

• A master protocol for testing cancer drugs in children and young adults

  This study is trying out different cancer drugs to see how well they work for children and young adults with cancer, using a flexible approach that allows for new treatments to be added as they become available.

  Recruiting at 52 sites Phase 2 Eli Lilly and Company · Birmingham, Alabama and 71 other locations · NCT05999994

• Nivolumab with chemotherapy for treating primary tracheal squamous cell carcinoma

  This study is testing whether combining a new immune therapy called Nivolumab with chemotherapy can help people with a rare type of throat cancer before surgery.

  Recruiting Phase 2 The First Affiliated Hospital of Guangzhou Medical University · Guangzhou, Guangdong · NCT05964101

• Evaluating HTL0039732 for Advanced Solid Tumours

  This study is testing a new drug called HTL0039732, alone and with another treatment, to see if it can help people with advanced solid tumors by boosting their immune response against cancer.

  Recruiting at 6 sites Phase 1/2 Cancer Research UK · Cambridge and 5 other locations · NCT05944237

• Treatment for advanced solid tumors with c-MET gene changes

  This study is testing a new drug called ABN401 to see if it can help people with advanced solid tumors that have c-MET gene changes when other treatments haven't worked.

  Recruiting Phase 2 Yonsei University · Seoul, Seoul · NCT05882292

• Using digital technology to manage chemotherapy-related nausea and vomiting in older adults

  This study is testing a digital program to help older adults manage nausea and vomiting while they go through chemotherapy to see if it improves their quality of life.

  Recruiting at 2 sites University of Central Florida · Miami, Florida and 1 other locations · NCT05838638

• Testing a new CAR T-cell therapy for patients with advanced B-cell cancers

  This study is testing a new CAR T-cell therapy to see if it can help adults with hard-to-treat B-cell cancers feel better and improve their health.

  Recruiting Phase 1 Technische Universität Dresden · Dresden · NCT05836896

• Preserving fertility in female cancer patients through ovarian tissue freezing

  This study is testing a method to freeze ovarian tissue for female cancer patients who don't have time for regular fertility preservation, helping them protect their ability to have children later.

  Recruiting Chinese University of Hong Kong · Hong Kong · NCT05830929

• CD7 CAR-T therapy followed by allogeneic stem cell transplant for relapsed/refractory CD7-positive blood cancers

  This will test whether CD7-directed CAR-T cells given before an allogeneic stem cell transplant are safe for adults with relapsed or refractory CD7-positive acute leukemias.

  Recruiting Phase 1/2 Zhejiang University · Hangzhou, Zhejiang · NCT05827835

• Combining low-dose and high-dose radiotherapy for metastatic cancer patients

  This study is testing if combining low-dose and high-dose radiotherapy can improve treatment outcomes for patients with metastatic cancer who are also receiving immunotherapy.

  Recruiting Soonchunhyang University Hospital · Seoul and 1 other locations · NCT05733156

• Treatment with STAR0602 for advanced solid tumors

  This study is testing a new treatment called STAR0602 to see if it can help people with advanced solid tumors by looking at how safe it is and how well it works.

  Recruiting at 16 sites Phase 1/2 Marengo Therapeutics, Inc. · Sacramento, California and 18 other locations · NCT05592626

• Evaluating MRI and biopsy methods for prostate cancer detection

  This study is testing whether a new type of MRI and a different way to do biopsies can help find prostate cancer more accurately in men who might have it.

  Recruiting at 14 sites Imperial College London · Southend-on-Sea, Essex and 14 other locations · NCT05574647

• A self-management program for Chinese cancer survivors

  This study is testing a self-management program to help Chinese cancer survivors feel better, manage their weight, and improve their overall quality of life after finishing treatment.

  Recruiting at 3 sites The University of Hong Kong · Hong Kong and 6 other locations · NCT05534386

• Evaluating cancer-associated fibroblasts using PET imaging

  This study is testing a new type of PET imaging to see if it can better help doctors understand and treat pancreatic and gastric cancer by looking at the supportive tissue around the tumors.

  Recruiting Osaka University · Suita, Osaka · NCT05442151

• Treatment options for Dupuytren's contracture

  This study is testing whether adding a corticosteroid injection to a needle treatment helps people with Dupuytren's contracture move their fingers better.

  Recruiting Phase 4 Regionshospitalet Silkeborg · Silkeborg · NCT05440240

• Combination treatment for brain metastasis from ER+/HER-2- breast cancer

  This study is testing a new combination treatment of elacestrant and abemaciclib to see if it can help people with brain metastases from estrogen receptor-positive, HER-2 negative breast cancer.

  Recruiting at 78 sites Phase 1/2 Stemline Therapeutics, Inc. · Fullerton, California and 85 other locations · NCT05386108

• Exploring exercise and molecular factors in cancer-related muscle loss

  This study tests whether exercise can help people with non-small cell lung cancer who are losing muscle mass feel better and improve their quality of life.

  Recruiting University of Copenhagen · Copenhagen, DK · NCT05307367

• Evaluation of a supportive care program for elderly patients with digestive cancer

  This study is testing whether a new supportive care program can help elderly patients with digestive cancer feel better during their chemotherapy or targeted therapy.

  Recruiting Centre Paul Strauss · Strasbourg · NCT05066139

• Long-term survival analysis of cancer patients after treatment

  This study looks at how well cancer patients do over the long term after different treatments to see what factors affect their survival.

  Recruiting Fudan University · Shanghai · NCT04996732

• Pooling clinical experiences of patients treated with Lutetium-177 in Spain

  This study looks at how well Lutetium-177 works and how safe it is for patients with certain types of tumors in Spain by collecting information from their medical records.

  Recruiting at 11 sites Sociedad Española de Medicina Nuclear e Imagen Molecular · Santiago de Compostela, A Coruña and 19 other locations · NCT04949282

• Evaluating health effects of modern radiotherapy in children

  This study is trying to see how modern radiation therapy affects the long-term health and quality of life of children under 22 who have received or will receive this treatment.

  Recruiting at 5 sites Institut National de la Santé Et de la Recherche Médicale, France · Leuven and 4 other locations · NCT04746729

• Observing cancer outcomes in patients receiving integrative oncology care

  This study is testing how well combining naturopathic medicine with regular cancer treatments helps early-stage and advanced-stage cancer patients live longer and stay healthy.

  Recruiting Advanced Integrative Medical Science Institute · Seattle, Washington · NCT04495790

• Registry for patients with unresectable pancreatic cancer treated with OncoSil™

  This study is testing how well the OncoSil™ device works and its safety for people with advanced pancreatic cancer who are also receiving chemotherapy.

  Recruiting at 5 sites OncoSil Medical Limited · Las Palmas de Gran Canaria and 8 other locations · NCT04493632

• Testing nilotinib and paclitaxel for rare cancers

  This study is testing a new combination of two drugs, nilotinib and paclitaxel, to see if it can help adults with rare solid tumors that haven't responded to other treatments.

  Recruiting Phase 2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT04449549

• Using gold markers and advanced MRI to improve bladder cancer treatment

  This study is testing if tiny gold markers and a new type of MRI can help doctors better target and treat bladder cancer while preserving the bladder.

  Recruiting at 3 sites Cedars-Sinai Medical Center · Los Angeles, California and 2 other locations · NCT04442724

• ProTarget — Danish nationwide targeted cancer treatment based on genomic profiling

  This study will try commercially available targeted cancer medicines chosen for adults with advanced cancer based on specific DNA or protein changes in their tumor.

  Recruiting Phase 2 Copenhagen University Hospital, Rigshospitalet · Aalborg, Aalborg and 6 other locations · NCT04341181

• Assessing the safety and tolerability of ABSK-021 in patients with advanced solid tumors

  This study is testing a new oral medication called ABSK-021 to see if it's safe and tolerable for people with advanced solid tumors, especially those with tenosynovial giant cell tumor, who haven't had success with other treatments.

  Recruiting at 3 sites Phase 1 Abbisko Therapeutics Co, Ltd · Beverly Hills, California and 16 other locations · NCT04192344

• Evaluating the impact of MR-guided radiation therapy on cancer treatment outcomes

  This study is testing how using a special type of radiation therapy with real-time imaging can improve treatment results and quality of life for adults with cancer.

  Recruiting at 14 sites UMC Utrecht · Pittsburgh, Pennsylvania and 17 other locations · NCT04075305

• Using reminders and self-sampling to boost cervical cancer screening participation

  This study is testing if sending text reminders and using self-sampling kits can help women at high risk for cervical cancer get screened more often.

  Recruiting at 6 sites Karolinska Institutet · Luleå, Norrbotten County and 5 other locations · NCT04061967

• Using a virus therapy to treat recurrent cerebellar brain tumors in children

  This study is testing a new virus treatment for children with recurring brain tumors to see if it can help them get better when combined with a low dose of radiation.

  Recruiting at 3 sites Phase 1 M.D. Anderson Cancer Center · Birmingham, Alabama and 2 other locations · NCT03911388

• Long-term follow-up for patients treated with gene-modified T cells

  This study is checking how well gene-modified T-cell therapy works and what side effects it might have for both kids and adults who have already received this treatment in the past.

  Recruiting at 175 sites Phase 2/3 Celgene · Birmingham, Alabama and 224 other locations · NCT03435796

• Testing a new drug for advanced solid tumors

  This study is testing a new drug called Aza-TdC to see if it can help people with advanced solid tumors that haven't improved with standard treatments.

  Recruiting Phase 1 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT03366116

• Investigating factors influencing cancer risk in people with Lynch syndrome

  This study is trying to find out how lifestyle, diet, and genetics affect cancer risk in people with Lynch syndrome.

  Recruiting Wageningen University · Wageningen · NCT03303833

• Collecting and tracking samples for cancer treatment evaluation

  This study is trying to see how different cancer treatments affect patients over time by collecting and tracking samples from their blood and tumors.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT03269578

• Registry for patients with myeloproliferative neoplasms

  This study is creating a database to gather information from people with myeloproliferative neoplasms to help improve treatments and outcomes for these rare blood cancers.

  Recruiting University Health Network, Toronto · Toronto, Ontario · NCT02760238

• Online registry to understand cancer experiences for patients and caregivers

  This study is trying to learn more about the experiences and needs of cancer patients and their caregivers by collecting their feedback through an online survey.

  Recruiting Cancer Support Community, Research and Training Institute, Philadelphia · Washington D.C., District of Columbia · NCT02333604

• Improving treatment planning for recurrent colorectal cancer using MRI

  This study is testing a new way to use MRI scans to help doctors plan better treatments for patients with recurrent colorectal cancer.

  Recruiting at 4 sites Imperial College London · Oslo and 3 other locations · NCT02292641

• Long-term tracking of Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy use

  This study is tracking how well Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy work for treating tumors over time to help improve patient care.

  Recruiting at 2 sites The Radiosurgery Society · Colorado Springs, Colorado and 12 other locations · NCT01885299

• Understanding Li-Fraumeni Syndrome and its Cancer Risks

  This study looks at people with Li-Fraumeni Syndrome to see what causes their cancer risk and how it affects their families, while also working on a cancer screening program.

  Recruiting at 2 sites National Institutes of Health Clinical Center (CC) · Bethesda, Maryland and 1 other locations · NCT01443468

• Registry for outcomes of radiation therapy in cancer patients

  This study is collecting information from cancer patients receiving different types of radiation therapy to see how well these treatments work and how safe they are.

  Recruiting at 29 sites Proton Collaborative Group · Scottsdale, Arizona and 28 other locations · NCT01255748

• Collection of tissue samples for cancer research

  This study is collecting tissue samples from adults and kids with cancer to help researchers learn more about the disease and improve treatments.

  Recruiting at 10 sites National Institutes of Health Clinical Center (CC) · Sacramento, California and 16 other locations · NCT00900198

• Project to improve detection of Barrett's Esophagus and related neoplasia

  This study is testing new ways to better detect Barrett's esophagus and early signs of cancer to help improve care for patients with this condition.

  Recruiting Midwest Veterans' Biomedical Research Foundation · Kansas City, Missouri · NCT00590239

• Measuring blood markers to monitor cancer treatment response

  This study is testing if certain blood markers can help doctors better understand how well cancer treatments are working for patients and predict their chances of recovery.

  Recruiting Stanford University · Stanford, California · NCT00349830

NIH-funded research (newest 40 of 52)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Biomarker clues to catch pancreatic cancer early in cysts

  A study from UC San Diego is testing blood and cyst-fluid markers to help tell high-risk pancreatic cysts from low-risk ones so that people with pancreatic cysts can get the right care sooner.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11420592

• Myeloproliferative Neoplasm Research Consortium

  A large research collaboration across multiple centers aims to improve survival for patients with myelofibrosis and related myeloproliferative neoplasms through coordinated laboratory, translational, and clinical work.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11399011

• Understanding how different CALR mutations drive certain blood cancers

  This grant explores how two CALR mutation types cause myeloproliferative neoplasms and could lead to better treatments for people with these blood cancers.

  NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11393750

• Cell Competition in Myeloproliferative Neoplasms

  This NIH grant explores how healthy and mutant blood stem cells interact in certain blood cancers to understand why some patients progress and how future therapies might help.

  NIH research State University New York Stony Brook · Stony Brook, United States · NIH-11380052

• Targeting ERK’s brake pedals to slow cancer progression

  Aims to block the parts of ERK signaling that speed up cancer progression, by guiding drugs to the substrate-binding domains that act like accelerator pedals in myeloproliferative neoplasms and related cancers.

  NIH research Research Inst of Fox Chase Can Ctr · Philadelphia, United States · NIH-11364927

• Biomarker work to predict pancreatic IPMN cancer risk

  A Duke University researcher is testing biomarkers to tell which pancreatic IPMN cysts are likely to become invasive cancer.

  NIH research Duke University · Durham, United States · NIH-11361607

• Understanding how inflammation and biology drive blood cancer evolution

  A large, multi-project program at Washington University is exploring how inflammatory signals and cell-intrinsic factors work together to drive progression of myeloproliferative neoplasms in people.

  NIH research Washington University · Saint Louis, United States · NIH-11348769

• Early blood changes and treatment-related leukemia risk after ovarian cancer

  This project follows ovarian cancer survivors to look for early blood cell changes that can lead to treatment-related leukemia.

  NIH research University of Washington · Seattle, United States · NIH-11324965

• Targeting abnormal Gαs signaling in myeloid blood cancers

  Researchers are developing ways to block harmful Gαs signaling in people with myelodysplastic syndromes and related acute myeloid leukemias linked to splicing-factor mutations.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11313828

• Treating bone marrow cancers linked to PARP inhibitor use in ovarian cancer survivors

  Researchers are developing new drug strategies to treat aggressive bone marrow cancers that can occur after PARP inhibitor therapy in ovarian cancer survivors.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11308742

• Real-time endoscopic imaging to better identify high-risk pancreatic cysts

  This project tests a new endoscopic imaging technique combined with AI to help doctors tell which branch-duct IPMN pancreatic cysts are likely to be cancerous.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11300204

• How a JAK2 mutation and missing genes on chromosome 20q make certain blood cancers worse

  Researchers will look at how the common JAK2V617F mutation together with loss of genes on chromosome 20q drive progression from polycythemia vera or essential thrombocythemia to myelofibrosis to find new treatment targets for people with these blood cancers.

  NIH research University of Virginia · Charlottesville, United States · NIH-11258551

• Overactive NF‑κB signaling in myeloproliferative neoplasms

  This project looks at whether blocking an overactive cell-signaling pathway called NF‑κB can slow or stop disease progression in people with myeloproliferative neoplasms.

  NIH research Washington University · Saint Louis, United States · NIH-11238087

• Blood chemical exposures and B‑cell blood cancer risk

  Researchers will use advanced blood chemical testing and AI to find environmental exposures linked to B‑cell blood cancers like non‑Hodgkin lymphoma and multiple myeloma.

  NIH research Emory University · Atlanta, United States · NIH-11233248

• Molecular pathogenesis and therapy for systemic histiocytic neoplasms

  This grant focuses on understanding and treating disorders like LCH, ECD, JXG, and RDD that involve abnormal MAPK signaling and BRAFV600E or related mutations.

  NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-11224806

• Mutant calreticulin in certain blood cancers (MPN)

  Looking for new treatments that target a mutant protein called calreticulin to help people with CALR‑mutant myeloproliferative neoplasms.

  NIH research Palo Alto Veterans Instit for Research · Palo Alto, United States · NIH-11189783

• How two types of CALR mutations drive myeloproliferative blood cancers

  This project compares how type 1 and type 2 CALR mutations change blood-cell behavior to help people with myeloproliferative neoplasms such as essential thrombocythemia, polycythemia vera, and myelofibrosis.

  NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11189677

• Blood and cyst-fluid tests to spot high-risk pancreatic cysts

  Testing whether blood and cyst-fluid tests can help people with pancreatic cysts detect early pancreatic cancer.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11184478

• Radiogenomics to identify which pancreatic cysts (IPMNs) are likely to become cancer

  This project combines CT scan features, AI, and blood markers to help people with pancreatic cysts (IPMNs) know which cysts are more likely to turn into cancer.

  NIH research H. Lee Moffitt Cancer Ctr & Res Inst · Tampa, United States · NIH-11176796

• Testing new blood and cyst fluid markers for pancreatic cysts

  This study is looking at new blood and fluid tests to help tell if pancreatic cysts are more likely to become cancerous, so if you have a pancreatic cyst, your participation could help improve early detection of pancreatic cancer.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11170341

• New T-Cell Treatment for CD4 Positive T-Cell Cancers

  This clinical trial is exploring a new type of T-cell treatment for people with certain CD4 positive T-cell cancers that have not responded to previous therapies.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11162445

• Understanding the differences between two types of mutations in a protein linked to blood cancers.

  This study is looking at how different mutations in a protein called calreticulin affect the progression of myeloproliferative neoplasms (MPNs) and aims to find new treatments, inviting patients with MPNs to help by participating in genetic testing and check-ups.

  NIH research University of Utah · Salt Lake City, United States · NIH-11158469

• How healthy and JAK2‑mutant blood stem cells compete in myeloproliferative neoplasms

  This work looks at whether healthy blood stem cells can keep JAK2‑mutant cells from taking over in people with myeloproliferative neoplasms.

  NIH research State University New York Stony Brook · Stony Brook, United States · NIH-11131232

• Using nanocages to deliver TGFb inhibitors for treating brain tumors

  This study is exploring a new way to treat glioblastoma, a tough type of brain cancer, by using tiny carriers to deliver a special treatment that helps boost the immune system's ability to fight the cancer, aiming to make current therapies work better and improve outcomes for patients.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11126743

• Tests to predict risk in children with liver tumors

  This project is creating lab tests to help doctors tell which children with liver tumors need stronger treatment and which can avoid it.

  NIH research Baylor College of Medicine · Houston, United States · NIH-11124124

• Targeting TET Enzymes for Blood Cancers

  This research explores new ways to treat blood cancers like myelodysplastic syndromes (MDS) by focusing on specific enzymes called TET, which play a role in how these diseases develop.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11123910

• Understanding how a cancer pathway works in blood cancers

  This research explores new ways to target a common cancer pathway in blood cancers by focusing on specific parts of a protein that act like "accelerator" and "brake" pedals.

  NIH research Research Inst of Fox Chase Can Ctr · Philadelphia, United States · NIH-11122246

• Understanding how genetic changes affect blood disorders and fibrosis progression

  This study is looking at how certain genetic changes, especially the JAK2VF mutation, affect the progression of myeloproliferative neoplasms (MPNs) and how well treatments work, with the hope of finding better ways to help patients like you.

  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11096109

• Improving early detection of high-risk pancreatic cysts

  This research aims to find better ways to tell which pancreatic cysts are likely to become cancer, helping doctors decide who needs treatment sooner.

  NIH research Duke University · Durham, United States · NIH-11095975

• Network for myelofibrosis and related blood cancers

  Doctors at multiple hospitals are testing new treatments to help people with myelofibrosis and related blood cancers live longer and feel better.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11094798

• Improving treatment for blood cancers in ovarian cancer survivors

  This study is looking for better treatment options for ovarian cancer patients who develop serious blood disorders after using certain medications, especially those with a specific gene mutation that makes standard treatments less effective, so they can live longer and feel better.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11082268

• Investigating blood disorders in ovarian cancer survivors

  This study is looking at how treatments for ovarian cancer might cause blood disorders later on, and it's for ovarian cancer survivors who want to help researchers find ways to prevent these issues and improve future treatments.

  NIH research University of Washington · Seattle, United States · NIH-11078343

• Understanding and treating systemic histiocytic neoplasms

  This study is looking at rare blood disorders called systemic histiocytic neoplasms to understand how certain genetic changes, like the BRAFV600E mutation, affect them, and it aims to find better treatments using targeted therapies; if you're a patient with this condition, your response to these treatments will be clos

  NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-11063105

• Investigating how mutant calreticulin affects blood cell disorders

  This study is looking at how certain changes in a protein called calreticulin affect blood cancers known as myeloproliferative neoplasms, with the hope of finding new ways to treat these conditions and improve patients' lives.

  NIH research Palo Alto Veterans Instit for Research · Palo Alto, United States · NIH-11060153

• Understanding how a specific mutation leads to blood cancers.

  This study is looking into how a specific gene mutation affects blood cancers called myeloproliferative neoplasms (MPNs) and aims to find new ways to improve treatments, which could help patients like you feel better.

  NIH research University of Virginia · Charlottesville, United States · NIH-11057744

• Using advanced imaging to improve diagnosis of pancreatic cysts

  This study is testing a new imaging technique to help doctors better understand pancreatic cysts, especially a type called IPMNs, so they can tell which ones need treatment and which ones are harmless, ultimately helping patients avoid unnecessary surgeries.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11057724

• Understanding how abnormal Gas activation affects blood cancer

  This study is looking into the genetic changes that cause blood cancers like acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) to help find new treatment options for patients.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11056848

• Using advanced imaging techniques to diagnose skin cancers without biopsies

  This study is working on a new way to help doctors spot skin cancers, especially in veterans who are more likely to get them, by using special imaging technology that can give quick and accurate results without needing a biopsy.

  NIH research VA Greater Los Angeles Healthcare System · Los Angeles, United States · NIH-11046554

• Investigating the role of a specific protein in blood cancers

  This study is looking at how a protein called PPM1D affects the progression of chronic blood disorders known as Myeloproliferative Neoplasms (MPNs) in patients with certain genetic changes, with the hope of finding new treatment options.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11032827

• Understanding how individual cancer cells develop in blood cancers.

  This study is looking at how certain changes in cancer cells can affect how myeloproliferative neoplasms (MPNs) show up in different patients, with the goal of finding better, personalized treatments based on the unique behavior of each person's cancer cells.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-11009051

Related topics

Quick answers

How many Neoplasms clinical trials are recruiting right now?

102, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 33 countries. The most sites are in United States (43 trials), France (19 trials), China (17 trials), Spain (16 trials), United Kingdom (16 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 20, Phase 2: 12, Phase 1/2: 8, Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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