Imaging tumors with a special radiodrug targeting HER2 protein
Official title: A Study to Evaluate 68Ga-Her2-affibody PET/CT Imaging of Her2 Expression in Tumors
Run by Peking University First Hospital · NCT06289517 · Data updated 2026-11-12
This study is testing a new imaging drug that targets the HER2 protein to see if it can help doctors better identify and understand different cancers, especially breast cancer.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Peking University First Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Status | Recruiting |
| Started | May 28, 2024 |
| Main results expected | July 30, 2025 |
| Study ends | August 30, 2025 |
| Registry record updated | December 18, 2024 |
| Trial ID | NCT06289517 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients with confirmed or suspected cancer who are willing to provide informed consent.
✕Probably not a fit
Patients without cancer or those who do not express HER2 may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project investigates the use of 68Ga-Her2-affibody, a radiodrug targeting the HER2 protein, to assess its diagnostic efficacy and safety in identifying HER2 expression in various cancers. The study aims to provide a novel imaging method that can enhance the determination of HER2 status in breast cancer and offer valuable insights for early diagnosis, accurate staging, and treatment decisions in other malignant tumors like lung, gastrointestinal, and bladder cancers. By utilizing PET imaging, the study seeks to gather comprehensive information that traditional biopsy methods may miss.
Why it matters
Potential benefit: If successful, this approach could lead to more accurate diagnoses and better treatment strategies for patients with HER2-positive cancers.
How similar studies have gone: Other studies have shown promise in using targeted imaging agents for cancer diagnostics, indicating potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: \- patients with confirmed or suspected cancer; Signed written informed consent Exclusion Criteria: \-
Where it's running
-
Peking University First Hospital
Beijing, Beijing Municipality, China Recruiting
Study contacts
- Study coordinator: Lei Yin, Dr
- Email: jack-yin@163.com
- Phone: +8610835725252
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
HR20013 for preventing nausea and vomiting in cancer patients receiving chemotherapy
This real-world study tests whether HR20013 helps prevent nausea and vomiting in adults with cancer who are getting chemotherapy.
-
Methylscape test in body fluids for multi-cancer detection in Colombia
A simple blood, urine, or saliva test called Methylscape is being tested to see if it can detect multiple cancers and identify where the signal is coming from, using people with cancer and healthy volunteers in Colombia.
-
Ready for Safe Cancer Treatment (RESET): A comprehensive perioperative program for surgical patients
The RESET program tests a structured, multidisciplinary perioperative plan to improve safety and recovery for adults having planned cancer surgery and older adults having planned non cancer-related surgery.
-
How environment and biology together predict health, aging, and death
Researchers are following adults to see how living conditions and biology together relate to aging and life expectancy, by linking personal health data with environmental and social information over time.
-
Metastatic liver cancer patient registry from multiple Chinese centers
This is a registry that collects real-world data on adults with liver metastases to understand patterns and prognosis and to support future research.
-
TriAdeno and N-803 vaccine in early prostate cancer on active surveillance
A vaccine combo called TriAdeno plus the N-803 drug is being tested to see if it can help slow or stop growth in men with early-stage, low- to intermediate-risk prostate cancer who are being watched rather than treated right away.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.