Proactive palliative care model for advanced cancer patients
ENABLE-SG (Educate, Nurture, Advise, Before Life Ends for Singapore) as a Proactive Palliative Care Model: Evaluation and Implementation Preparation
This study tests a new telehealth support program for advanced cancer patients and their caregivers to see if it helps them feel better and manage their care more effectively compared to regular treatment.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 715 (estimated) |
| Ages | 21 Years to 120 Years |
| Sex | All |
| Sponsor | National Cancer Centre, Singapore Academic / other |
| Locations | 1 site (Singapore) |
| Trial ID | NCT06044441 on ClinicalTrials.gov |
What this trial studies
This study evaluates the ENABLE-SG model, a proactive telehealth approach designed to support patients with advanced cancer and their caregivers early in the disease trajectory. Participants will be randomly assigned to receive either the ENABLE-SG intervention or usual care, with outcomes assessed at 6 and 12 months. The study aims to improve health-related quality of life, mood, and coping strategies for both patients and caregivers while reducing healthcare utilization and costs. The implementation of the model will be guided by the Consolidated Framework for Implementation Research to enhance its effectiveness.
Who should consider this trial
Good fit: Ideal candidates include adults aged 21 and above who have been diagnosed with advanced cancer within the last 60 days and can communicate in English or Chinese.
Not a fit: Patients who are not within 60 days of an advanced cancer diagnosis or those who cannot communicate in English or Chinese may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve the quality of life and coping mechanisms for patients and caregivers dealing with advanced cancer.
How similar studies have performed: Previous studies using similar proactive palliative care models have shown positive health outcomes, indicating a promising approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Inclusion criteria for patients: 1. Adult aged 21 and above 2. Within 60 days of being informed of an advanced cancer diagnosis, defined as metastatic or recurrent/ progressive Stage III/IV solid tumour 3. Able to speak English or Chinese 4. Able to provide informed consent 5. Patients will NOT need to have a caregiver willing to participate in the ENABLE-SG programme. * Inclusion criteria for caregivers: 1. Adult aged 21 and above 2. Self-endorsing or identified by the enrolled patient as an unpaid spouse/partner, relative or friend who knows them well and who provides regular support (at least 7 hours a week) due to their cancer and who does not have to live in the same dwelling 3. Caring for a patient with advanced cancer (see definition under patient inclusion criteria above) 4. Able to speak English or Chinese. 5. Able to provide informed consent * Inclusion criteria for healthcare professions: 1. 21 years or older. 2. Approached to participate in the ENABLE-SG study 3. Able to provide informed consent Exclusion Criteria: * Exclusion criteria for patients: 1. Medical record documentation of an active severe mental illness, dementia, active suicidal ideation, uncorrected hearing loss 2. Unable to complete patient-reported outcome measures 3. Has been reviewed by palliative care services in the current model of palliative care. * Exclusion criteria for caregivers: 1. Self-reported severe mental illness, dementia, active suicidal ideation, uncorrected hearing loss 2. Unable to complete caregiver-reported outcomes. * Exclusion criteria for healthcare professional: 1. Healthcare professionals that are not providing care for cancer patients. 2. Unable to complete interviews.
Where this trial is running
Singapore
- National Cancer Centre Singapore — Singapore, Singapore (Recruiting)
Study contacts
- Principal investigator: Grace M Yang, MRCP — National Cancer Centre, Singapore
- Study coordinator: Grace M Yang, MRCP
- Email: grace.yang.m.j@singhealth.com.sg
- Phone: +65 63065844
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.