Condition

Breast Neoplasms clinical trials and research

• 109Clinical trials
• 1New in 30 days
• 55Countries

Newest Breast Neoplasms clinical trials

All recruiting trials (109)

• Improved Facial Skin Quality After VYC-12L for Breast Cancer Survivors

  This study tests whether intradermal injections of VYC-12L can improve facial skin quality and quality of life in adults who have completed breast cancer treatment.

  Recruiting Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia · Murcia, Murcia · NCT07917117

• Breast cancer subtypes and outcomes in Colombian women

  This study looks back at medical records of women with breast cancer to see how different molecular subtypes relate to survival and recurrence in a single Colombian hospital.

  Recruiting Fundación Santa Fe de Bogota · Bogotá, Bogota D.C. · NCT07856225

• Multimodal psychosomatic symptom care for breast cancer: personalized acupuncture care guided by shared decision-making

  This study tests whether personalized acupuncture options (manual acupuncture, ear acupuncture, or both) can help women with breast cancer who have anxiety, sleep problems, or fatigue, compared to routine nursing care.

  Recruiting at 3 sites First Teaching Hospital of Tianjin University of Traditional Chinese Medicine · Tianjin and 2 other locations · NCT07763587

• Slow Jogging for Breast Cancer Survivors

  This study tests whether a 12-week slow jogging program helps sleep quality in women who have completed breast cancer treatment.

  Recruiting Mackay Memorial Hospital · Taipei, Taipei City · NCT07757763

• Methylscape test in body fluids for multi-cancer detection in Colombia

  A simple blood, urine, or saliva test called Methylscape is being tested to see if it can detect multiple cancers and identify where the signal is coming from, using people with cancer and healthy volunteers in Colombia.

  Recruiting Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo · Bogotá, Bogota D.C. · NCT07741435

• Benchmarking AI language models against tumor boards for oncology treatment decisions

  This project tests whether frontier AI language models can match the treatment recommendations of multidisciplinary tumor boards for common cancers using standardized synthetic cases.

  Recruiting Assistance Publique - Hôpitaux de Paris · Boulogne-Billancourt and 4 other locations · NCT07739121

• AI-powered pre-treatment MRI to predict chemotherapy response in HR+/HER2- breast cancer

  This study tests whether AI analysis of baseline DCE-MRI can forecast which HR+/HER2- breast cancer patients will benefit most from neoadjuvant chemotherapy.

  Recruiting at 5 sites Fujian Cancer Hospital · Fuzhou, Fujian and 4 other locations · NCT07702708

• Breast ultrasound screening for older women in community clinics

  This study tests whether offering breast ultrasound to women aged 65–80 in local communities helps find breast cancers earlier than usual care.

  Recruiting The First Affiliated Hospital with Nanjing Medical University · Kunshan, Jiangsu and 1 other locations · NCT07698366

• AI-based prediction of five major diseases using integrated health data

  Researchers are testing an AI model to see if they can predict the onset of five major diseases in adults 30–65 by combining medical records with biospecimens and lifestyle data.

  Recruiting Asan Medical Center · Seoul, Seoul Special City · NCT07595718

• Fluorocholine PET/MR imaging in breast cancer patients before treatment

  This study tests whether pre-treatment FCH PET/MR imaging markers can help predict breast cancer subtypes and likely outcomes in women.

  Recruiting Taipei Veterans General Hospital, Taiwan · Taipei, Taiwan · NCT07587086

• Dalpiciclib plus hormone therapy for early HR+/HER2- breast cancer

  This trial tests whether adding dalpiciclib at two different doses and durations to standard hormone therapy helps people with early HR+/HER2- breast cancer.

  Recruiting Phase 2 Fujian Cancer Hospital · Fuzhou, Fujian and 1 other locations · NCT07581834

• ATUSA 3D automated breast ultrasound for suspicious breast lesions

  This study will test whether the ATUSA 3D automated breast ultrasound system can produce high-quality images that match biopsy results in women with BI-RADS 4 or 5 breast findings.

  Recruiting at 2 sites iSono Health, Inc. · Sacramento, California and 1 other locations · NCT07505797

• Benchmark and performance test for AI reading breast ultrasound images

  This project will test whether multimodal AI models can read breast ultrasound images to help classify normal, benign, and malignant findings for people who have had breast ultrasound.

  Recruiting Peking Union Medical College Hospital · Beijing · NCT07500428

• Tracking body composition changes after breast cancer treatment

  This project will see how muscle mass and fat distribution change over two years in adults treated for stage I–III breast cancer.

  Recruiting Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation · New Taipei City, Xindian Dist · NCT07472803

• Prehabilitation plus ongoing exercise and nutrition support for women with breast cancer

  This trial will test whether a short supervised pre-treatment program of high-intensity exercise and personalized nutrition followed by home-based exercise and dietary guidance helps newly diagnosed women with stage 0–III breast cancer recover better and tolerate treatment.

  Recruiting at 2 sites European University Miguel de Cervantes · Valladolid, Valladolid and 1 other locations · NCT07467824

• Supervised clinic resistance plus relaxation versus home resistance exercise to improve life after breast cancer

  This trial tests whether a supervised clinic program combining elastic-band resistance exercise and progressive muscle relaxation helps post-treatment breast cancer survivors more than a self-guided home resistance program.

  Recruiting Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation · New Taipei City, Xindian Dist · NCT07465393

• ICG imaging of lymphatic changes before and after breast radiotherapy

  This study will use ICG lymphography to see if early lymphatic changes after radiotherapy predict later arm swelling in women treated for stage I–III breast cancer.

  Recruiting Dongtan Sacred Heart Hospital · Hwaseong-si, Gyeonggido · NCT07297927

• HandX-assisted endoscopic nipple-sparing mastectomy (ATHENA I)

  This study tests whether a handheld robotic device called HandX can help surgeons safely perform a minimally invasive nipple-sparing mastectomy with immediate implant reconstruction for women having therapeutic or risk-reducing mastectomy.

  Recruiting Mediterraneo Hospital · Glyfada, Attica · NCT07292246

• Imlunestrant in Premenopausal ER+ HER2- Early Breast Cancer

  This study tests imlunestrant in premenopausal women with ER+ HER2- early breast cancer to see how it works with or without ovarian suppression compared to tamoxifen.

  Recruiting at 25 sites Phase 2 Eli Lilly and Company · Birmingham, Alabama and 89 other locations · NCT07287098

• Gut microbiome differences in people on abemaciclib who do or don't get diarrhea

  This project will compare gut bacteria in people with HR-positive breast cancer who are taking abemaciclib to see if differences are linked to developing diarrhea.

  Recruiting Hubei Cancer Hospital · Wuhan, Hubei · NCT07264998

• Monitoring blood markers during DIEP flap breast reconstruction

  We will see if measuring inflammation and oxidative stress markers in blood before and during the first 72 hours after DIEP flap reconstruction helps map recovery patterns for women having immediate breast reconstruction after mastectomy.

  Recruiting Hubei Cancer Hospital · Wuhan, Hubei · NCT07263347

• Capecitabine with or without elacestrant for ER-positive advanced breast cancer

  This trial will try adding elacestrant to capecitabine to see if it helps people with ER-positive, HER2-negative advanced breast cancer that stopped responding to CDK4/6 inhibitors.

  Recruiting Phase 2 Dana-Farber Cancer Institute · Boston, Massachusetts · NCT07222215

• Signatera‑guided timing of CDK4/6 inhibitor (ribociclib) with hormone therapy for intermediate‑risk HR+/HER2‑ breast cancer

  This trial will test whether using Signatera ctDNA testing to time when to start a CDK4/6 inhibitor alongside hormone therapy can help adults with intermediate‑risk HR+/HER2‑ early breast cancer avoid unnecessary treatment while keeping cancer control.

  Recruiting at 14 sites Natera, Inc. · Phoenix, Arizona and 49 other locations · NCT07214532

• LY4337713 for people with FAP-positive ovarian, breast, pancreatic, colorectal, or esophageal cancers

  This trial tests LY4337713, a FAP-targeted lutetium-177 therapy, in people with advanced cancers that show high levels of fibroblast activation protein (FAP).

  Recruiting at 17 sites Phase 1 Eli Lilly and Company · Newport Beach, California and 29 other locations · NCT07213791

• Machine-learning prediction of heart damage from anthracycline or HER2 cancer therapies

  We will see if a machine-learning score can predict which adults starting anthracycline or HER2-targeted cancer therapies will develop heart damage within one year.

  Recruiting University Hospital, Caen · Caen · NCT07191730

• Tersolisib plus standard anti-cancer medicines for advanced HR+/HER2- breast cancer with a PIK3CA change

  This trial tests whether adding tersolisib to standard first-line anti-cancer medicines helps people with advanced hormone receptor–positive, HER2‑negative breast cancer that has a PIK3CA mutation.

  Recruiting at 179 sites Phase 3 Eli Lilly and Company · Anchorage, Alaska and 363 other locations · NCT07174336

• Pumitamig plus chemotherapy for metastatic triple-negative breast cancer

  This trial will test whether adding pumitamig to standard chemotherapy helps people with metastatic or inoperable triple-negative breast cancer who are not eligible for PD(L)1 combo therapy.

  Recruiting at 224 sites Phase 3 BioNTech SE · Springdale, Arkansas and 223 other locations · NCT07173751

• DPYD-guided fluoropyrimidine dose adjustment for patients with one DPYD gene variant

  This trial will test whether giving lower doses of fluoropyrimidine chemotherapy based on a patient's DPYD gene result reduces severe (Grade 3–4) side effects in people with colorectal, breast, or head and neck cancers who carry one DPYD variant.

  Recruiting at 12 sites Phase 4 Rutgers, The State University of New Jersey · Belleville, New Jersey and 11 other locations · NCT07158164

• First-in-human imaging test with Ga-DWJ155 in advanced breast cancer and NSCLC

  This early-phase study tests a radioactive imaging agent, 68Ga-DWJ155, to see how it distributes in the body and how well it images tumors in adults with HR+/HER2-, HER2+, or NSCLC adenocarcinoma.

  Recruiting Phase 1 Novartis · Groningen, Provincie Groningen · NCT07117214

• LY4257496 for GRPR-positive advanced breast, colorectal, prostate, and endometrial cancer (OMNIRAY)

  This Phase 1 test tries LY4257496, with GRPR imaging using LY4257529 and sometimes standard treatments, to see if it is safe and helps people with GRPR-positive advanced breast, colorectal, prostate, or endometrial cancer.

  Recruiting at 15 sites Phase 1 Eli Lilly and Company · Duarte, California and 32 other locations · NCT07114601

• Adaptive chemotherapy for advanced breast cancer after standard treatment

  This tests whether tailoring chemotherapy choices (gemcitabine, vinorelbine, eribulin, or utidelone) can improve outcomes for people whose advanced breast cancer has progressed after standard treatments.

  Recruiting Phase 3 Sun Yat-sen University · Guangzhou, Guangdong · NCT07088263

• AI screening tool using WhatsApp to predict genetic risk for breast cancer

  This project will test whether an AI-based WhatsApp virtual assistant can use family cancer history to predict which women referred for genetic evaluation have higher genetic risk for breast cancer.

  Recruiting AstraZeneca · Golania, Goiás and 2 other locations · NCT07070128

• Single-session very accelerated partial breast radiation (sfVAPBI)

  This trial will test whether one high-dose, catheter-based radiation session after surgery can control early-stage breast cancer with acceptable side effects and cosmetic results.

  Recruiting at 8 sites National Institute of Oncology, Hungary · Lyon and 22 other locations · NCT07067437

• Patritumab deruxtecan for HR+/HER2- unresectable locally advanced or metastatic breast cancer

  This trial tests whether patritumab deruxtecan helps people with hormone receptor–positive, HER2‑negative advanced breast cancer who have progressed on CDK4/6 inhibitor plus endocrine therapy live longer or have slower cancer growth compared with standard chemotherapy.

  Recruiting at 203 sites Phase 3 Merck Sharp & Dohme LLC · Daphne, Alabama and 205 other locations · NCT07060807

• Adding MRI diffusion and mammogram micro‑calcifications to the Kaiser Score for BI-RADS 4 breast lesions

  This project will test whether adding MRI diffusion measurements and mammogram micro‑calcification findings to the Kaiser Score can better identify which BI‑RADS 4 breast lesions need a biopsy.

  Recruiting Mansoura University Hospital · Al Mansurah · NCT07033507

• Radiology-based prediction of HER2 level and T‑DXd benefit in metastatic breast cancer

  This study tests whether patterns in CT or FDG‑PET images can show HER2 level and help predict response to trastuzumab deruxtecan for people with metastatic breast cancer.

  Recruiting Fondazione IRCCS Istituto Nazionale dei Tumori, Milano · Milan · NCT07030569

• How local breast cancer treatments affect side effects and quality of life in Chinese patients

  This project will test how surgery and related treatments (chemotherapy, radiation, hormone or targeted therapy) affect side effects and daily quality of life for people with early-stage breast cancer in China.

  Recruiting Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Beijing, Beijing Municipality and 2 other locations · NCT07010939

• Nipple reconstruction with cross-linked hyaluronic acid after mastectomy

  This trial will test whether adding a cross-linked hyaluronic acid injection to areola micropigmentation helps women who had a mastectomy achieve better nipple projection, appearance, and satisfaction.

  Recruiting Germans Trias i Pujol Hospital · Badalona, Barcelona · NCT07008339

• Augmented reality (SKIA-Breast) localization for guiding breast-conserving surgery

  The trial will test whether an augmented reality system (SKIA-Breast) can guide breast-conserving surgery as well as conventional ultrasound skin marking for women with a single, biopsy-proven invasive breast tumor 5–30 mm in size.

  Recruiting at 3 sites SKIA Inc. · Seoul, Gangseo-gu and 2 other locations · NCT07003841

• Preventing Dato‑DXd–related mouth sores with dexamethasone mouthwash

  This study will see if using an alcohol‑free dexamethasone mouthwash can prevent mouth sores in adults with advanced breast cancer or non‑squamous non‑small cell lung cancer who are receiving datopotumab deruxtecan.

  Recruiting Phase 2 Brown University · Providence, Rhode Island · NCT06974604

• Sacituzumab tirumotecan plus pembrolizumab and chemotherapy for high-risk early triple-negative and HR-low/HER2-negative breast cancer

  This trial will test whether adding sacituzumab tirumotecan and pembrolizumab to chemotherapy helps people with high‑risk early-stage triple‑negative or HR‑low/HER2‑negative breast cancer have fewer cancer cells in their tumors and lymph nodes before surgery.

  Recruiting at 331 sites Phase 3 Merck Sharp & Dohme LLC · Gilbert, Arizona and 334 other locations · NCT06966700

• Using cryotherapy to prevent eyebrow and eyelash loss in breast cancer patients undergoing chemotherapy

  This study is testing whether cryotherapy can help breast cancer patients keep their eyebrows and eyelashes while they undergo chemotherapy.

  Recruiting at 2 sites University of Salamanca · Santander, Cantabria and 1 other locations · NCT06955702

• Developing a database for breast cancer patients with depression

  This study is trying to build a database that collects health information and gut bacteria data from breast cancer patients who have depression to see how it can help improve their diagnosis and treatment.

  Recruiting Xiangya Hospital of Central South University · Changsha, Hunan · NCT06938373

• Izalontamab brengitecan versus chemotherapy for first-line metastatic triple-negative or ER-low, HER2-negative breast cancer in patients not eligible for anti-PD(L)1 drugs

  This trial tests whether iza-bren (izalontamab brengitecan), a bi‑specific antibody‑drug conjugate, works better than standard chemotherapy as first-line treatment for people with metastatic triple‑negative or ER‑low, HER2‑negative breast cancer who cannot receive anti‑PD(L)1 drugs.

  Recruiting at 168 sites Phase 2/3 Bristol-Myers Squibb · Hot Springs, Arkansas and 294 other locations · NCT06926868

• Exploring treatment strategies for HER2-low breast cancer using antibody-drug conjugates

  This study looks at how different treatment plans using antibody-drug conjugates can help people with HER2-low breast cancer and what factors might affect their outcomes.

  Recruiting Sun Yat-sen University · Guangzhou, Guangdong · NCT06877416

• Exploring how couples cope with breast cancer

  This study looks at how couples handle the challenges of breast cancer over two years to see what helps them cope and stay strong together.

  Recruiting Regina Elena Cancer Institute · Roma, Rome · NCT06875414

• Evaluating ribociclib with aromatase inhibitors for early breast cancer treatment

  This study is testing if combining ribociclib with an aromatase inhibitor can help people with early breast cancer feel better and reduce their risk of the cancer coming back.

  Recruiting at 285 sites Novartis · Wiener Neustadt, Lower Austria and 286 other locations · NCT06830720

• Predicting outcomes for advanced breast cancer patients treated with CDK4/6 inhibitors and endocrine therapy

  This study is trying to see how well different CDK4/6 inhibitors combined with hormone therapy work for people with advanced breast cancer and how safe they are.

  Recruiting at 24 sites Fondazione IRCCS Istituto Nazionale dei Tumori, Milano · Aviano and 23 other locations · NCT06805812

• New treatment approach for high-risk early-stage breast cancer

  This study is testing a new combination of treatments for people with high-risk early-stage triple-negative breast cancer to see if it can shrink tumors more than the usual treatment before surgery.

  Recruiting at 17 sites Phase 2 Merck Sharp & Dohme LLC · Santa Monica, California and 16 other locations · NCT06797635

• Using a fluorescent dye to improve breast-conserving surgery outcomes in breast cancer patients

  This study is testing a special dye to see if it can help doctors find hard-to-locate breast tumors better during surgery for breast cancer patients.

  Recruiting National Cancer Center, Korea · Goyang-si, Gyeonggi-do · NCT06780735

• Understanding breast cancer risk factors and outcomes in Florida

  This study is trying to understand the different risk factors and outcomes of breast cancer in men and women in Florida by collecting samples and survey information from new patients at breast clinics.

  Recruiting at 2 sites Memorial Sloan Kettering Cancer Center · Los Angeles, California and 2 other locations · NCT06780176

• Radiation before mastectomy with immediate breast reconstruction

  This trial tests whether giving radiation before mastectomy combined with immediate breast reconstruction improves cosmetic results and quality of life for women who need mastectomy and post‑mastectomy radiation.

  Recruiting at 4 sites Cancer Research Antwerp · Edegem, Antwerpen and 5 other locations · NCT06739655

• Partial breast reconstruction using chest wall perforator flaps

  This study looks at how well partial breast reconstruction using chest wall flaps works for women who have had surgery for early-stage breast cancer.

  Recruiting Cambridge University Hospitals NHS Foundation Trust · Cambridge, Cambridgeshire · NCT06728527

• Ovarian suppression combined with exercise and nutrition for breast cancer treatment

  This study is testing whether a program that combines exercise, healthy eating, and emotional support can help premenopausal women with localized breast cancer manage their weight and improve their overall health while they undergo ovarian suppression therapy.

  Recruiting at 2 sites Universidad Pontificia Comillas · Madrid and 1 other locations · NCT06727487

• Imaging method for breast cancer using targeted PET scans

  This study is testing a new type of PET scan that targets specific proteins in breast cancer to see if it can help doctors better identify and understand the disease.

  Recruiting Phase 1/2 RenJi Hospital · Shanghai, Shanghai Municipality · NCT06715826

• Treatment of advanced HER2 positive breast cancer with patritumab deruxtecan and other agents

  This study is testing a new treatment combining patritumab deruxtecan with other cancer drugs to see if it helps people with advanced HER2 positive breast cancer that can't be surgically removed.

  Recruiting at 18 sites Phase 1/2 Merck Sharp & Dohme LLC · Aurora, Colorado and 17 other locations · NCT06686394

• Mesothelin-targeted CAR T-cell therapy for esophagogastric cancer

  This study is testing a new treatment that uses modified immune cells to target and attack tumors in people with advanced esophagogastric cancer.

  Recruiting at 7 sites Phase 1 Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT06623396

• Telerehabilitation for managing complications after breast cancer surgery

  This study is testing if telerehabilitation can help women who have had breast cancer surgery avoid complications like pain and movement issues better than regular care.

  Recruiting Fondazione Policlinico Universitario Campus Bio-Medico · Roma, Roma · NCT06608446

• Treatment for breast cancer that has spread to the liver using a new ablation technique

  This study is testing a new treatment method for breast cancer that has spread to the liver to see if it works better than the standard approach.

  Recruiting Ruijin Hospital · Shanghai · NCT06567353

• Weight loss treatment for early breast cancer using tirzepatide

  This study is testing if the weight loss drug tirzepatide can help overweight or obese women with early breast cancer live longer and healthier by reducing harmful tumor markers in their blood.

  Recruiting Phase 2 Baylor Research Institute · Dallas, Texas · NCT06517212

• Organoids to predict treatment outcomes for breast cancer metastases

  This project will try to grow mini-tumors (organoids) from people with breast cancer metastases to see if lab responses predict each patient’s response to radiation and chemotherapy.

  Recruiting at 2 sites King's College London · London and 1 other locations · NCT06468124

• Omitting chest wall radiation after breast reconstruction

  This study is testing if skipping chest wall radiation after breast reconstruction can help early-stage breast cancer patients have better recovery and quality of life without raising the chances of cancer coming back.

  Recruiting Phase 2 Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang · NCT06464913

• Investigating the effects of SGLT2 inhibitors on heart issues from breast cancer treatment

  This study is testing if a diabetes medication can help protect the hearts of women with localized breast cancer who are receiving certain chemotherapy treatments.

  Recruiting Centre Paul Strauss · Strasbourg · NCT06443645

• Preoperative exercise to prevent lymphedema in breast cancer patients

  This study is testing if a special exercise program before surgery can help breast cancer patients avoid lymphedema after chemotherapy.

  Recruiting Asan Medical Center · Seoul, Seoul Special City · NCT06421285

• 68Ga-FAPI-46 versus 18F-FDG PET imaging in ER-positive breast cancer

  This test compares whether 68Ga-FAPI-46 PET scans find more cancer spread than standard 18F-FDG PET scans in people with ER-positive breast cancer who need staging.

  Recruiting Phase 2 Maastricht University Medical Center · Maastricht · NCT06335069

• Comparing two methods of breast reconstruction using the latissimus dorsi muscle

  This study is testing two different ways to use a muscle from the back for breast reconstruction in women who don't want implants after cancer surgery to see which method leads to better satisfaction and results.

  Recruiting Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT06319157

• Examining the gut microbiome in women with early triple-negative breast cancer receiving immunotherapy

  This study is testing how the gut bacteria of overweight or obese women with early triple-negative breast cancer affects their response to a specific immunotherapy treatment.

  Recruiting Pennington Biomedical Research Center · Baton Rouge, Louisiana · NCT06318507

• Combining capecitabine with camrelizumab for treating specific triple-negative breast cancer

  This study is testing if combining a new drug called camrelizumab with capecitabine can help people with triple-negative breast cancer live longer and healthier after not responding fully to initial treatment.

  Recruiting Phase 3 Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT06313463

• Comparing sacituzumab tirumotecan and pembrolizumab to standard treatment for advanced breast cancer

  This study is testing if a new treatment combining sacituzumab tirumotecan and pembrolizumab can help people with advanced breast cancer live longer without their disease getting worse compared to standard treatments.

  Recruiting at 181 sites Phase 3 Merck Sharp & Dohme LLC · Chandler, Arizona and 258 other locations · NCT06312176

• Preoperative lifestyle intervention for breast cancer patients

  This study is testing a new program that combines exercise and nutrition to see if it helps breast cancer patients feel stronger and healthier before their surgery.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT06266312

• Tailoring axillary surgery for breast cancer patients

  This study is testing if some early breast cancer patients can skip certain surgeries to remove lymph nodes, which might help them avoid unnecessary complications and costs.

  Recruiting KK Women's and Children's Hospital · Singapore · NCT06259513

• Treatment for elderly patients with advanced triple-positive breast cancer

  This study is testing a new combination treatment for elderly patients with advanced triple-positive breast cancer to see if it is safe and effective for them.

  Recruiting Second Affiliated Hospital of Soochow University · Suzhou, Jiangsu · NCT06235931

• Using ultrasound to assess soft tissue changes after breast cancer treatment

  This study tests if regular 2D ultrasound can help understand how breast cancer treatment changes soft tissue around the breast and arm in patients, especially looking at those who have or don’t have arm problems.

  Recruiting Universiteit Antwerpen · Antwerp · NCT06180642

• Using immune cells from lymph nodes to treat HER2-negative breast cancer

  This study is testing if using immune cells from lymph nodes can help women with HER2-negative breast cancer who didn't respond to initial chemotherapy feel better before surgery.

  Recruiting Phase 1 Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT06121570

• Using immune cells from lymph nodes to treat advanced HER2-negative breast cancer

  This study is testing whether using immune cells taken from lymph nodes can help people with advanced HER2-negative breast cancer feel better when combined with chemotherapy.

  Recruiting Phase 1 Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT06121557

• Biennial contrast-enhanced mammography for women with a history of breast cancer

  This study is testing if using a special type of mammogram every two years along with yearly 3D breast scans can help women with a history of breast cancer find any new cancers more effectively than just the yearly scans alone.

  Recruiting at 6 sites University of Pittsburgh · Bethel Park, Pennsylvania and 5 other locations · NCT06105749

• Impact of Radiation Therapy on Lung Function in Breast Cancer Patients

  This study is testing how radiation therapy affects lung function in breast cancer patients to help create better ways to prevent and treat lung problems after their treatment.

  Recruiting Meshalkin Research Institute of Pathology of Circulation · Novosibirsk, Novosibirsk Oblast · NCT06069115

• Comparing cold dissection and electrocautery in nipple-sparing mastectomy with reconstruction

  This study is testing whether using cold dissection instead of electrocautery during nipple-sparing mastectomy can lead to fewer complications and better cosmetic results for patients getting breast reconstruction.

  Recruiting Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT06024187

• Using immune cells from lymph nodes to treat HER2-negative breast cancer

  This study is testing if using immune cells from lymph nodes can help women with HER2-negative breast cancer who didn't respond to their first round of chemotherapy feel better before surgery.

  Recruiting Phase 1/2 Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT05981014

• Using immune cells from lymph nodes to treat advanced HER2-negative breast cancer

  This study is testing a new treatment using immune cells from lymph nodes to see if it can help people with advanced HER2-negative breast cancer when other options are limited.

  Recruiting Phase 1/2 Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT05981001

• Using trilaciclib for early-stage HR-negative breast cancer patients receiving chemotherapy

  This study is testing if the drug trilaciclib can help early-stage hormone receptor-negative breast cancer patients have fewer severe side effects from chemotherapy.

  Recruiting Phase 2 Sun Yat-sen University · Guangzhou, Gangdong · NCT05978648

• Electrical stimulation to relieve chemotherapy-related nerve pain in breast cancer patients

  This study is testing whether a special electrical treatment can help breast cancer patients who have nerve pain from chemotherapy feel better.

  Recruiting National Taipei University of Nursing and Health Sciences · Changhua, Changhua · NCT05904340

• Preoperative tumor-bed boost followed by oncoplastic surgery for early stage breast cancer

  This study is testing if giving a special dose of radiation to the tumor area before surgery can help younger patients with early stage breast cancer have better surgery results and fewer side effects.

  Recruiting Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Beijing, Beijing Municipality · NCT05603078

• Observing patient outcomes in breast cancer patients treated with trastuzumab deruxtecan

  This study is looking to see how well trastuzumab deruxtecan works for people with certain types of advanced breast cancer and how they feel about their treatment.

  Recruiting at 105 sites AstraZeneca · Amberg and 108 other locations · NCT05573893

• Erector spinae plane block for managing pain after breast cancer surgery

  This study is testing if a special nerve block combined with a medication can help reduce pain and improve recovery for women after breast cancer surgery.

  Recruiting at 2 sites Peking University First Hospital · Beijing, Beijing Municipality and 1 other locations · NCT05494502

• New treatment approach for BRCA1/2 mutated triple negative breast cancer

  This study is testing a new treatment combining Olaparib and Pembrolizumab for people with BRCA1/2 mutated triple negative breast cancer to see if it works better after chemotherapy.

  Recruiting at 3 sites Phase 2 Okayama University · Gifu, Gifu and 2 other locations · NCT05485766

• Neoadjuvant radiation therapy for locally advanced breast cancer

  This study is testing if adding radiation therapy to chemotherapy can help patients with locally advanced breast cancer who can't have surgery feel better and have more treatment options.

  Recruiting Phase 2 Fudan University · Shanghai, Shanghai Municipality · NCT05479409

• Comparing utidelone and docetaxel for advanced breast cancer

  This study is testing whether a new drug called utidelone works better than docetaxel for women with advanced breast cancer that is HER2-negative.

  Recruiting Phase 3 Sun Yat-sen University · Guangzhou, Gangdong and 1 other locations · NCT05430399

• Combination treatment for brain metastasis from ER+/HER-2- breast cancer

  This study is testing a new combination treatment of elacestrant and abemaciclib to see if it can help people with brain metastases from estrogen receptor-positive, HER-2 negative breast cancer.

  Recruiting at 78 sites Phase 1/2 Stemline Therapeutics, Inc. · Fullerton, California and 85 other locations · NCT05386108

• Online yoga's effects on breast cancer patients' quality of life

  This study is testing whether two types of online yoga can improve the quality of life for women with non-metastatic breast cancer.

  Recruiting Charite University, Berlin, Germany · Berlin, State of Berlin · NCT05327543

• Evaluating tumor cell characteristics in breast cancer patients

  This study is testing if tracking certain tumor cells in breast cancer patients can help predict how well they respond to treatment after chemotherapy and surgery.

  Recruiting Hunan Cancer Hospital · Changsha, Hunan · NCT05326295

• Treatment adjustment for HER2 positive breast cancer after initial therapy

  This study is testing if adjusting treatment for early HER2 positive breast cancer based on blood tests can help patients do better after their initial therapy.

  Recruiting Phase 2 AC Camargo Cancer Center · São Paulo · NCT04993014

• Combining Pyrotinib and ARX788 for treating HER2-positive breast cancer

  This study is testing a new combination of two drugs, pyrotinib and ARX788, to see if it can help women with stage II-III HER2-positive breast cancer who haven't responded well to other treatments.

  Recruiting Phase 2 Shengjing Hospital · Shenyang, Liaoning · NCT04983121

• Exercise intervention to improve cognitive function in breast cancer survivors

  This study tests whether a 6-month aerobic exercise program can help improve memory and attention in post-menopausal breast cancer survivors compared to those who only receive health education.

  Recruiting Mayo Clinic · Phoenix, Arizona · NCT04816006

• Using nanoparticles for delayed lymph node biopsy in breast cancer patients

  This study is testing if using special nanoparticles can help breast cancer patients avoid unnecessary surgery by identifying important lymph nodes only when needed.

  Recruiting at 9 sites Phase 3 Uppsala University · Houston, Texas and 8 other locations · NCT04722692

• Long-term niraparib treatment for people who completed a prior GSK/TESARO niraparib protocol

  This extension lets people with ovarian or breast cancer who finished a GSK/TESARO niraparib protocol keep taking niraparib to see if it remains safe over the long term.

  Recruiting at 18 sites Phase 2 GlaxoSmithKline · Tucson, Arizona and 24 other locations · NCT04641247

• Using patient avatars to guide treatment for metastatic breast cancer

  This study is testing whether using patient avatars made from biopsy samples can help find the best treatments for people with metastatic breast cancer.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT04608357

• Registry for Intra-Operative Radiotherapy in Early Stage Breast Cancer

  This study is trying to see if a new type of radiation treatment given during breast surgery is safe and effective for women with early stage breast cancer compared to the usual radiation therapy.

  Recruiting Saint John's Cancer Institute · Santa Monica, California · NCT04603209

• Detecting circulating tumor cells in patients with luminal A breast cancer

  This study is testing if checking for circulating tumor cells in the blood can help doctors better monitor and treat women with luminal A breast cancer after surgery.

  Recruiting at 2 sites Shengjing Hospital · Shenyang, Liaoning and 1 other locations · NCT04065321

• Registry for pregnancy and fertility in young breast cancer patients

  This study is trying to learn more about how young women with breast cancer can preserve their fertility and manage pregnancy-related issues.

  Recruiting at 20 sites IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy · Asti, Asti and 22 other locations · NCT02895165

• Registry for patients with advanced or metastatic breast cancer

  This study is creating a registry to collect health information from patients with advanced or metastatic breast cancer to better understand how the disease is managed and what outcomes patients experience.

  Recruiting at 39 sites Spanish Breast Cancer Research Group · Elche, Alicante and 39 other locations · NCT02819882

• Testing personalized cancer treatments using patient-derived tumors in mice

  This study is trying to see if using personalized tumor samples from patients with certain types of cancer in mice can help find the best treatments for those patients.

  Recruiting University Health Network, Toronto · Toronto, Ontario · NCT02732860

• Evaluating heart health risks after breast cancer radiotherapy

  This study is trying to see if newer radiotherapy techniques for breast cancer can lower the risk of heart problems compared to traditional methods in patients over 15 years.

  Recruiting at 2 sites St. Olavs Hospital · Ålesund and 1 other locations · NCT02541435

• Endocrine therapy for older women with operable breast cancer

  This study is testing if hormone therapy alone can effectively treat older women with early-stage breast cancer, so they might not need extra treatments.

  Recruiting Phase 2 Washington University School of Medicine · St Louis, Missouri · NCT02476786

• Genomic profiling of breast cancer in Sweden

  This study looks at the genetic makeup of breast cancer in over 20,000 patients in Sweden to see how it can help tailor treatments and improve outcomes for those affected.

  Recruiting at 8 sites Lund University · Borås and 9 other locations · NCT02306096

• Creating a bank of tumor tissue samples for research

  This study is creating a collection of tumor tissue samples from cancer patients and healthy individuals to help researchers find better ways to diagnose and treat cancer.

  Recruiting Medical University of Vienna · Vienna and 2 other locations · NCT01789229

• Creating a tumor bank for blood samples from cancer patients and healthy controls

  This study is collecting blood samples from cancer patients and healthy people to help researchers find better ways to diagnose and treat cancer.

  Recruiting Medical University of Vienna · Innsbruck and 5 other locations · NCT01763125

• Personalized treatment for breast cancer using new drug agents

  This study is testing new drug combinations with standard chemotherapy to see which treatments work best for different types of breast cancer based on the specific characteristics of each patient's tumor.

  Recruiting at 32 sites Phase 2 QuantumLeap Healthcare Collaborative · Birmingham, Alabama and 41 other locations · NCT01042379

• Comparing tumor markers in breast cancer patients before and after chemotherapy

  This study is trying to see if certain tumor markers in breast cancer patients can help predict how well they respond to chemotherapy and if they might have a higher chance of the cancer coming back.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT00353483

Related topics

Quick answers

How many Breast Neoplasms clinical trials are recruiting right now?

109, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 55 countries. The most sites are in China (37 trials), United States (27 trials), Spain (17 trials), Germany (16 trials), Italy (15 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 16, Phase 3: 9, Phase 1: 6, Phase 1/2: 5. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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