Ready for Safe Cancer Treatment (RESET): A comprehensive perioperative program for surgical patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomised, two-center study compares the RESET multimodal perioperative care pathway with standard perioperative care. It includes adults undergoing planned oncologic surgery and adults aged 70+ undergoing planned non-oncologic surgery under general anesthesia, with a 9:1 allocation favoring RESET. RESET spans prehabilitation, in-hospital care, recovery, discharge planning, and post-discharge follow-up, organized into four interconnected modules. The trial assesses postoperative complications, hospital stay length, readmissions, overall health status, physical function, quality of life, safety, and recovery. Outcomes are measured within an integrated pathway rather than as isolated components.

Why it matters

Who can join: the full rules

ONCOLOGY GROUP

Inclusion Criteria:

* Age ≥ 18 years
* Qualification for admission to surgical departments with an ICD10 diagnosis for radical cancer surgery
* Preliminary qualification for one of the procedures listed in Section II.B.23
* Informed consent to participate in the study

Exclusion Criteria:

* Age \< 18 years
* Qualification for admission to surgical departments with an ICD10 diagnosis for diagnostic procedures to identify cancer
* Pregnancy or breastfeeding

NON-ONCOLOGY GROUP

Inclusion Criteria:

* Informed consent to participate in the study
* Age ≥ 70 years
* All consecutive patients referred for planned non-oncological surgical procedures, not solely diagnostic, performed under general anesthesia

Exclusion Criteria:

\- Diagnosis of cancer

Where it's running

• 4th Military Clinical Hospital in Wroclaw
  Wroclaw, Lower Silesian Voivodeship, Poland Recruiting
• Regional Specialist Hospital in Wrocław
  Wroclaw, Lower Silesian Voivodeship, Poland Recruiting

Study contacts

• Principal investigator: Małgorzata Wierzbicka, Professor — Regional Specialist Hospital in Wroclaw
• Study coordinator: Natalia Jędruchniewicz, PhD
• Email: natalia.jedruchniewicz@wssk.wroc.pl
• Phone: +48713270538

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.