How environment and biology together predict health, aging, and death
Official title: The Human Observatory: A Prospective Individual and Population-Level Study of Aging, Health, and Longevity
Run by Longevity Metrics, Inc. · NCT07646782 · Data updated 2026-11-12
Researchers are following adults to see how living conditions and biology together relate to aging and life expectancy, by linking personal health data with environmental and social information over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000000 (estimated) |
| Sponsor | Longevity Metrics, Inc. Industry-sponsored |
| Locations | 1 site (Boulder, Colorado) |
| Status | Recruiting |
| Started | April 25, 2026 |
| Main results expected | December 31, 2099 |
| Study ends | December 31, 2099 |
| Registry record updated | September 8, 2026 |
| Trial ID | NCT07646782 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults enrolled in the 100-Year Human Aging Study at any site or who complete the online health screener with geographic data and consent.
✕Probably not a fit
Children under 18 and individuals who do not consent or provide necessary geographic data may not benefit from study insights.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational study that combines individual health measurements with continuous environmental and social data to build a dynamic model of health and aging. Participants provide multi-system health information at clinical sites, while environmental, demographic, and mortality data are collected from public and private sources across multiple geographic scales. The study aims to generate screening insights and population-level forecasts grounded in real-time biology and causal environmental factors. It uses a dual-layer approach to connect personal biology with the broader context in which health occurs. No experimental interventions are applied; the goal is to better understand how environment and biology interact to influence aging and mortality.
Why it matters
Potential benefit: If successful, the study could improve risk prediction and personalized screening by combining biological data with environmental context.
How similar studies have gone: Previous work in integrated biosocial models shows promise, but this project advances environment-biome links at both individual and population levels.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Enrolled in the 100-Year Human Aging Study at any fixed or mobile clinical site; OR completion of online health screener with provision of geographic anchor data and consent. Exclusion Criteria: * Age under 18 years (current protocol; pediatric amendment planned).
Where it's running
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Longevity Metrics
Boulder, Colorado, United States Recruiting
Study contacts
- Principal investigator: William Brandenburg, MD — Longevity Metrics
- Study coordinator: William Brandenburg, MD
- Email: info@longevitymetrics.org
- Phone: 13035010016
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.