Testing new blood and cyst fluid markers for pancreatic cysts
Official title: Biomarker Validation in Pancreatic Cystic Neoplasms
Funded at University of California, San Diego · NIH-11170341 · Data updated 2026-11-12
This study is looking at new blood and fluid tests to help tell if pancreatic cysts are more likely to become cancerous, so if you have a pancreatic cyst, your participation could help improve early detection of pancreatic cancer.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | September 15, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $820,061 |
| NIH project number | 7U01CA282272-02 |
| Project ID | NIH-11170341 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with pancreatic cystic neoplasms, particularly those with cysts larger than 2.5 cm or those under surveillance.
✕Less likely to help
Patients without pancreatic cystic neoplasms or those with cysts deemed low-risk may not benefit from this research.
What this research studies
This research focuses on pancreatic cystic neoplasms (PCNs), which are often found incidentally and can have a risk of becoming cancerous. The study aims to validate new blood-based and cyst fluid biomarkers that could help distinguish between high-risk and low-risk PCNs. By using rigorous testing methods, the researchers will evaluate the effectiveness of these biomarkers in identifying early pancreatic cancer. Patients with PCNs will be monitored through imaging and sample collection to assess the performance of these markers.
Why it matters
Potential benefit: If successful, this research could lead to more accurate detection of pancreatic cancer, reducing unnecessary surgeries and improving early diagnosis.
How similar studies have gone: Previous research has shown promise in using biomarkers for cancer detection, suggesting that this approach could yield significant advancements.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Simeone, Diane M — University of California, San Diego
- Study coordinator: Simeone, Diane M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.