Condition

Glioma clinical trials and research

• 124Clinical trials
• 240NIH research projects
• 2New in 30 days
• 29Countries

Newest Glioma clinical trials

All recruiting trials (124)

• YN003 injection in glioma patients

  This phase 1 study tests whether YN003 injected IV is safe and tolerable for adults with recurrent or progressive glioma, and to explore how the drug behaves in the body and any early signs of activity.

  Recruiting at 2 sites Phase 1 Beijing Inno Medicine Co., Ltd. · Los Angeles, California and 4 other locations · NCT07929909

• Brain connectome project in adults with brain glioma undergoing surgery

  This registry collects MRI data and clinical information from adults with glioma to see how brain networks relate to surgery and recovery.

  Recruiting Northwell Health · New York, New York · NCT07927595

• Proton vs. Photon Radiation for Certain Grade 2–3 Gliomas

  This study tests whether proton therapy can better preserve thinking and memory than photon therapy for adults with IDH-mutated grade 2–3 gliomas who need radiation.

  Recruiting at 2 sites University Hospital, Essen · Essen and 1 other locations · NCT07750457

• Connectome-guided network planning for brain tumor surgery in eloquent areas

  This study tests whether using patient-specific brain network maps from diffusion MRI can help surgeons plan and guide brain tumor removal in eloquent areas.

  Recruiting ARNAS Civico Di Cristina Benfratelli Hospital · Palermo, PA · NCT07717827

• AI-powered analysis of brain MRI to help glioma care

  Doctors will use AI to study existing MRI scans and patient data from adults with glioma to see if it can help with non-invasive diagnosis and treatment planning.

  Recruiting Università degli Studi di Trento · Trento · NCT07703761

• Safusidenib in IDH1-mutant glioma after vorasidenib progression

  This trial tests safusidenib in people with IDH1-mutant glioma who progressed on vorasidenib and did not need immediate chemo or radiation.

  Recruiting at 2 sites Phase 2 Nuvation Bio Inc. · Los Angeles, California and 11 other locations · NCT07703436

• HF1K16 with Bevacizumab for recurrent or progressive glioma

  This study tests whether HF1K16 plus Bevacizumab can help adults with recurrent or progressive glioma and whether the combo is safe.

  Recruiting Phase 2 HighField Biopharmaceuticals Corporation · Shanghai, Shanghai Municipality · NCT07678684

• Methionine-Reduced Diet in Solid Tumors (early-phase)

  A small pilot study will test whether a methionine-reduced diet can change blood levels in adults with various solid tumors who are receiving standard cancer therapy.

  Recruiting Early Phase 1 University of California, Irvine · Orange, California · NCT07628634

• Patient experiences during treatment for IDH‑mutant grade 2 gliomas: vorasidenib, radiotherapy, or observation

  This project will test how adults with IDH‑mutant grade 2 gliomas feel—their quality of life, treatment symptoms, and anxiety—when they receive vorasidenib, radiotherapy, or active surveillance.

  Recruiting Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta · Milan · NCT07547163

• Sitagliptin plus bevacizumab for recurrent grade 4 glioma

  This study tests whether adding sitagliptin to bevacizumab can help people whose recurrent glioblastoma or other grade 4 gliomas respond to treatment and to find a safe dose when used with bevacizumab.

  Recruiting Phase 1 University of Iowa · Iowa City, Iowa · NCT07541781

• Mirdametinib for people with central nervous system tumors

  This trial tests whether mirdametinib is safe and can help adults with central nervous system tumors, including glioma and neurohistiocytosis.

  Recruiting at 7 sites Phase 1/2 Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT07539441

• Language Network Prehab with fMRI Neurofeedback before Glioma Surgery

  This study tests whether brief fMRI neurofeedback before glioma surgery can help shift language brain activity away from tumor-affected areas.

  Recruiting Yale University · New Haven, Connecticut · NCT07488780

• Olutasidenib drug interaction testing for IDH1‑mutant cancers

  This trial tests whether the cancer drug olutasidenib changes how the body processes other medicines in adults with IDH1‑mutation positive cancers.

  Recruiting at 2 sites Phase 4 Rigel Pharmaceuticals · Orange, California and 1 other locations · NCT07486713

• CIPHER System use during brain tumor surgery

  A first-in-human test to see if the CIPHER System can be safely used to map and stimulate brain tissue during glioma surgery in adults.

  Recruiting Coherence Neuro Australia Pty Limited · Melbourne, Victoria · NCT07465796

• Phase 1 safety and dose-finding of GLIX1 for adults with recurrent or progressive high-grade glioma

  This trial will test whether taking oral GLIX1 daily is safe, tolerable, and shows early anti-tumor activity in adults with recurrent or progressive high-grade glioma.

  Recruiting at 4 sites Phase 1 Tetragon Biosciences Ltd · Palo Alto, California and 3 other locations · NCT07464925

• Symptom patterns and gut bacteria in childhood cancer survivors

  This project will test whether groups of ongoing symptoms in childhood cancer survivors are linked to differences in gut bacteria and their metabolites.

  Recruiting The Children's Hospital of Zhejiang University School of Medicine · Hangzhou, Zhejiang · NCT07450872

• Dabrafenib and trametinib for rare cancers with BRAF V600 mutations

  This arm tests whether dabrafenib and trametinib can help adults, children, and teens with cancers that have a BRAF V600 mutation.

  Recruiting at 15 sites Phase 2/3 Cancer Research UK · Belfast and 26 other locations · NCT07440290

• LMP744 (an indenoisoquinolone) for people with recurrent glioblastoma

  This trial will test whether the drug LMP744 can shrink tumors or slow progression in adults whose glioblastoma has returned after prior treatment.

  Recruiting Phase 1/2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT07416188

• Skin closure after brain tumor surgery: running absorbable versus interrupted non-absorbable sutures

  This will test whether absorbable running intradermal sutures or non-absorbable interrupted transdermal sutures produce better wound healing after craniotomy in adults with supratentorial brain tumors.

  Recruiting Medical University of Warsaw · Warsaw, Masovian Voivodeship · NCT07413796

• Cerebrospinal fluid leak after brain tumor surgery

  This project will look at adults having planned supratentorial craniotomy for intracranial tumors to see how often cerebrospinal fluid leaks occur and what complications they cause.

  Recruiting Medical University of Warsaw · Warsaw · NCT07411690

• IDH-targeted PET/MRI for diagnosing and grading gliomas

  This project tests whether an IDH-targeted PET/MRI scan can find IDH mutations in adults with suspected or known glioma to help with diagnosis, grading, and treatment planning.

  Recruiting Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Chongqing, Chongqing Municipality · NCT07405372

• Amino acid transporter PET/CT imaging with MET/FET for AATS-related tumors

  This project tries PET/CT scans using 11C- or 18F-labeled MET/FET tracers to see if they better find primary or metastatic lesions in adults with amino acid transporter–related tumors such as glioma and primary hyperparathyroidism.

  Recruiting at 3 sites Tianjin Medical University · Hefei, Anhui and 2 other locations · NCT07379463

• GLOW400-assisted neurosurgery for high-grade gliomas

  This PMCF study tests whether the GLOW400 digital fluorescence accessory used with the ARveo8x microscope helps surgeons see tumor tissue during elective surgery for suspected high-grade gliomas.

  Recruiting at 2 sites Leica Microsystems (Schweiz) AG · Porto and 1 other locations · NCT07366892

• PET-guided short-course higher-dose radiotherapy with temozolomide for poor-prognosis glioblastoma

  This trial will try a shorter, higher-dose PET-guided radiotherapy schedule plus temozolomide in people aged 50 and older with poor-prognosis, IDH‑wildtype glioblastoma who are not candidates for surgery to see if it helps them live longer.

  Recruiting Tata Memorial Centre · Mumbai, Maharashtra · NCT07338539

• Silevertinib plus temozolomide for newly diagnosed GBM with unmethylated MGMT and EGFRvIII

  This trial tests whether adding silevertinib to standard temozolomide helps people with newly diagnosed glioblastoma that have EGFRvIII and an unmethylated MGMT promoter live longer without the cancer getting worse.

  Recruiting at 38 sites Phase 2 Black Diamond Therapeutics, Inc. · Birmingham, Alabama and 37 other locations · NCT07326566

• Tracking visuospatial difficulties over time in people with parietal lobe glioma

  This project will test whether visuospatial problems in adults with parietal lobe glioma get better, worse, or stay the same before and after surgical removal of the tumor.

  Recruiting Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta · Milan · NCT07286929

• AI prediction of glioma molecular markers from pathology images

  This project will test whether an AI model can use routine pathology images to predict key molecular changes in adults with glioma.

  Recruiting Nanfang Hospital, Southern Medical University · Guangzhou, Guangdong · NCT07263711

• Tarlatamab plus temozolomide for DLL3-positive high-grade brain and other CNS tumors

  This trial tests whether adding the experimental immunotherapy tarlatamab to a fixed, low-dose temozolomide schedule helps adolescents and adults (≥12 years) with DLL3-positive recurrent or refractory high-grade brain and other CNS tumors.

  Recruiting at 8 sites Phase 1/2 Centre Leon Berard · Angers and 11 other locations · NCT07243470

• Vorasidenib treatment for adults with WHO Grade 2 IDH‑mutant diffuse glioma

  This study will try vorasidenib in adults with IDH1- or IDH2-mutant WHO grade 2 diffuse glioma after surgery to see if it affects quality of life and clinical outcomes.

  Recruiting iOMEDICO AG · Heidelberg · NCT07240662

• Home-based mobile neurological check for people with brain tumors

  This project will test whether people with brain tumors older than 5 can use the Iskhaa Android app to do guided self-neurological exams, upload short videos, and have an AI model detect changes that might predict neurological worsening.

  Recruiting Tata Memorial Centre · Mumbai, Maharashtra · NCT07236840

• 177Lu-PSMA-617 treatment for IDH‑wildtype gliomas

  This trial will test whether the radiopharmaceutical 177Lu-PSMA-617 is safe for adults with IDH‑wildtype gliomas who have completed standard surgery and radiation.

  Recruiting at 7 sites Phase 1 Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT07223034

• Fluorescent-labeled nivolumab (Nivo800) imaging for high-grade glioma surgery

  This trial tests whether a near-infrared fluorescent version of the immunotherapy drug nivolumab can be given before planned surgery to visualize drug distribution in adults with suspected high-grade glioma.

  Recruiting Early Phase 1 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT07210632

• Focused ultrasound to open the blood-brain barrier in adults with high-grade glioma on chemotherapy

  This trial tests whether focused ultrasound using the Next Generation Dome Helmet can safely open the blood-brain barrier in adults with glioblastoma who are receiving maintenance temozolomide chemotherapy.

  Recruiting Phase 1 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07179328

• AI-designed TAMAVAQ personalized vaccine for newly diagnosed glioma

  This will test an AI-designed personalized peptide vaccine (TAMAVAQ) in adults with newly diagnosed glioma to see if it is safe and triggers an immune response against each patient's tumor.

  Recruiting Early Phase 1 Biogenea Pharmaceuticals Ltd. · Thessaloniki · NCT07077616

• Intratumoral M032 (IL-12-expressing engineered HSV-1) for newly diagnosed diffuse midline glioma after radiation

  This will test whether injecting M032, a modified herpes virus that produces IL-12, directly into the tumor is safe and how it affects children and adults with newly diagnosed diffuse midline glioma after they finish radiation.

  Recruiting Phase 1 M.D. Anderson Cancer Center · Houston, Texas · NCT07076498

• Home-based digital platform delivering sequential therapy for people with glioma

  This program will test a mobile app that helps deliver and remotely monitor home-based systemic therapy for adults with newly diagnosed or recurrent glioma.

  Recruiting at 2 sites Mayo Clinic · Jacksonville, Florida and 1 other locations · NCT07074756

• Sequenced or combined dasatinib, quercetin, fisetin, and temozolomide for adults with previously treated glioma and remaining tumor

  This trial will try different sequences or combinations of dasatinib, the plant compounds quercetin and fisetin, and the chemotherapy temozolomide to see if they are safe and help adults with previously treated glioma that still has residual tumor.

  Recruiting Early Phase 1 Mayo Clinic · Rochester, Minnesota · NCT07025226

• Capmatinib treatment for adults with cancers having MET gene changes

  This study is testing if capmatinib, a drug for lung cancer, can help adults with different types of cancers that have changes in the MET gene.

  Recruiting at 16 sites Phase 2/3 Cancer Research UK · Belfast and 16 other locations · NCT06988475

• Dual-nuclide PET/CT imaging to test simultaneous tracer separation in cancer patients and healthy volunteers

  This study tests a simultaneous dual-tracer PET/CT imaging method in prostate cancer, neuroendocrine tumors, glioma, lung cancer patients, and healthy volunteers to see if it can accurately separate and measure two tracers in humans.

  Recruiting Xijing Hospital · Xi'an, Shaanxi · NCT06914427

• Examining miRNA Signatures in Glioma for Clinical Use

  This study is testing how certain tiny molecules in the body affect glioma tumors and their response to treatments like radiation and a common chemotherapy drug, to help improve care for glioma patients.

  Recruiting Regina Elena Cancer Institute · Rome, Rome · NCT06883214

• Using electroacupuncture to enhance chemotherapy delivery for recurrent glioma

  This study is testing if a special type of acupuncture can help deliver a chemotherapy drug more effectively to people with recurrent high-grade glioma who haven't had success with other treatments.

  Recruiting Phase 2 The Third Affiliated hospital of Zhejiang Chinese Medical University · China, Hangzhou City, Zhejiang Province · NCT06818331

• Pharmacoscopy-guided treatment for refractory brain tumors

  This trial tests whether personalized drug testing on a patient’s tumor cells can guide treatment choices for adults with hard-to-treat brain cancers like glioblastoma.

  Recruiting Phase 2 University of Zurich · Basel, Basel-Landschaft and 2 other locations · NCT06804655

• Using irinotecan liposomes with bevacizumab to treat recurrent glioma

  This study is testing if a new combination of irinotecan liposomes and bevacizumab can help people with recurrent brain glioma feel better and live longer after their first treatment didn’t work.

  Recruiting Phase 2 The Central Hospital of Lishui City · Lishui, Zhejiang · NCT06801730

• Understanding brain blood flow and metabolism in patients with brain lesions

  This study is trying to understand how blood flow and metabolism in the brain are affected in patients with brain tumors like glioblastoma, glioma, and astrocytoma.

  Recruiting Erasme University Hospital · Brussels · NCT06797661

• Identifying biomarkers to predict cognitive decline after radiation therapy for brain tumors

  This study is trying to find specific markers in blood and spinal fluid from young patients with brain tumors to see if they can predict problems with thinking and memory after radiation treatment.

  Recruiting Tata Memorial Centre · Mumbai, Maharashtra · NCT06779487

• BC008-1A injections for recurrent WHO grade 4 glioma

  This trial tests whether BC008-1A, a bispecific antibody that targets PD‑1 and TIGIT, is safe and shows early anti-tumor activity in adults with recurrent WHO grade 4 glioma.

  Recruiting Phase 1 Sichuan Luzhou Buchang Biopharmaceutical Co., Ltd. · Beijing, Beijing Municipality · NCT06773481

• Craniospinal irradiation for pediatric glioma treatment

  This study is testing if a special type of radiation treatment can help kids with aggressive brain tumors live longer and have a better quality of life.

  Recruiting Tata Memorial Centre · Mumbai · NCT06720727

• Testing HX301 with Temozolomide for high-grade glioma

  This study is testing a new drug called HX301 combined with Temozolomide to see if it can help people with high-grade glioma feel better and fight their cancer more effectively.

  Recruiting Phase 1/2 Hangzhou Hanx Biopharmaceuticals, Ltd. · Beijing, Beijing Municipality · NCT06703255

• Imaging brain tumors using a targeted radioimmunoconjugate and PET scans

  This study is testing a new imaging method using a special drug to see if it can help identify immune cells in patients with brain tumors before they have surgery.

  Recruiting Phase 1 Jonsson Comprehensive Cancer Center · Los Angeles, California · NCT06650163

• Combining TIL Therapy and Pembrolizumab for Advanced Brain Cancer

  This study is testing a new treatment that combines a type of immune therapy using patients' own tumor cells with Pembrolizumab to see if it helps people with advanced brain cancer feel better and live longer.

  Recruiting Phase 1/2 Essen Biotech · Beijing, Beijing Municipality · NCT06640582

• Using AI to Improve Treatment for Gliomas

  This study is testing whether using artificial intelligence to analyze genetic data from patients with gliomas can help find more effective treatment options.

  Recruiting at 3 sites Centro di Riferimento Oncologico - Aviano · Aviano, Pordenone and 2 other locations · NCT06620055

• Intraoperative neuronal recordings during brain tumor surgery

  This study tries out a Neuropixel probe to record brain activity during awake tumor removal in adults with glioma or brain metastases to explore how neurons interact with tumors.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06617208

• Monitoring low-grade gliomas using blood samples

  This study is testing if analyzing blood samples can help monitor patients with low-grade brain tumors for signs of recurrence better than current MRI methods.

  Recruiting University Hospital, Caen · Caen · NCT06610851

• Measuring brain glucose use with deuterated glucose by MRS in glioma

  This study tests whether using deuterated glucose with 1H MRS can reveal how glioma brain tissue takes up and processes glucose.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06594315

• Using the Epitranscriptome to Diagnose and Treat Diffuse Gliomas

  This study tests whether analyzing epitranscriptomic marks from tumor tissue and body samples can help diagnose and guide treatment for adults with suspected diffuse gliomas undergoing surgery.

  Recruiting at 2 sites Institut du Cancer de Montpellier - Val d'Aurelle · Montpellier, Hérault and 1 other locations · NCT06575452

• Investigating factors affecting blood cell toxicity in glioma patients treated with temozolomide

  This study is trying to find out why some glioma patients have serious blood cell problems when treated with the chemotherapy drug temozolomide, so that treatments can be safer and more effective.

  Recruiting University College Cork · Cork · NCT06546631

• Evaluating Bevacizumab with Focused Ultrasound for Recurrent Glioblastoma

  This study is testing if adding focused ultrasound to the standard treatment of Bevacizumab can help people with recurrent glioblastoma feel better and live longer.

  Recruiting at 2 sites Phase 3 NaviFUS Corporation · Taipei and 1 other locations · NCT06496971

• Proton pulsed reduced-dose-rate radiotherapy for recurrent high-grade glioma

  This trial tests whether a special proton radiation method called PRDR helps people whose fast-growing glioma has come back after prior radiation.

  Recruiting Baptist Health South Florida · Boca Raton, Florida and 1 other locations · NCT06397560

• Improving glioma surgery and quality of life through personalized motor rehabilitation

  This study is testing if personalized motor rehab before surgery can help people with lower-grade gliomas have better surgery results and improve their quality of life.

  Recruiting University of Milan · Milan, Lombardy · NCT06381726

• Re-irradiation for recurrent glioblastoma

  This study is testing a new way to safely give radiation treatment again to adults with recurring glioblastoma to see if it can improve their options after their tumors come back.

  Recruiting Phase 1 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT06344130

• Electroacupuncture and Paclitaxel for High-Grade Glioma Recurrence

  This study is testing whether combining acupuncture with a special cancer drug can help people with recurring high-grade glioma feel better when other treatments haven't worked.

  Recruiting Phase 3 The Third Affiliated hospital of Zhejiang Chinese Medical University · Zhejiang · NCT06330337

• Investigating NST-628 Oral Tablets for Patients with Solid Tumors

  This study is testing a new oral medication called NST-628 to see if it can safely help adults with advanced solid tumors that have specific genetic mutations.

  Recruiting at 18 sites Phase 1 Nested Therapeutics, Inc · San Francisco, California and 22 other locations · NCT06326411

• Testing PLX038 for brain and spinal cord tumors with MYC or MYCN amplifications

  This study is testing a new treatment called PLX038 for adults with brain and spinal cord tumors that have specific gene changes to see if it helps improve their condition.

  Recruiting Phase 1/2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT06161519

• Investigating B7-H4's Role in Glioma Vaccine Response

  This study is trying to see how a protein called B7-H4 affects the response to cancer vaccines in people with glioma to help find better treatment options.

  Recruiting Huashan Hospital · Shanghai, Shanghai Municipality · NCT06156150

• Detecting molecular abnormalities in glioma exosomes

  This study is testing whether analyzing tiny particles from the blood of glioma patients can provide better information about their tumors compared to a standard test.

  Recruiting University Hospital, Limoges · Limoges · NCT06116903

• Tumor vaccines for treating glioma and solid tumors

  This study is testing whether a new type of vaccine made from immune cells can help people with brain tumors live longer and feel better.

  Recruiting Huashan Hospital · Shanghai, Shanghai Municipality · NCT06102837

• Using MRI to Differentiate Between Brain Tumors and Radiation Effects

  This study is testing a new MRI technique to see if it can help tell the difference between brain tumors and radiation damage in people who have had radiation therapy.

  Recruiting at 2 sites Case Comprehensive Cancer Center · Cleveland, Ohio and 1 other locations · NCT06101069

• ASCENT: an ACT-based support program for adults with malignant brain tumors

  This project will test whether a six-session ACT-based coaching program (ASCENT) helps adults newly diagnosed with malignant brain tumors manage distress and cope better.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT06099743

• Pulsed low-dose rate re-irradiation for recurrent glioma

  This study is testing a new way of giving radiation therapy to people with recurrent gliomas to see if it can help treat their condition safely while reducing side effects.

  Recruiting Centro di Riferimento Oncologico - Aviano · Aviano, Pordenone · NCT06055517

• Combining brain stimulation and cognitive training to improve thinking skills in glioma patients

  This study is testing if combining brain stimulation with thinking skills training can help adults with glioma improve their cognitive abilities.

  Recruiting Amsterdam UMC, location VUmc · Amsterdam · NCT06043765

• Analyzing brain tumors using advanced imaging techniques

  This study is testing how advanced imaging techniques can help doctors better understand and classify gliomas, a type of brain tumor, by looking at past medical images from patients.

  Recruiting Tata Memorial Centre · Mumbai, Maharashtra · NCT06036381

• Exploring tumor stiffness and adhesion in gliomas using magnetic resonance elastography

  This study is testing whether measuring the stiffness of glioma tumors with a special imaging technique can help doctors understand their characteristics better and improve treatment for patients.

  Recruiting Shengjing Hospital · Shenyang, Liaoning · NCT05990244

• Using omental tissue to treat recurrent glioblastoma

  This study is testing whether using a piece of fat from the abdomen can help improve treatment for patients with recurrent glioblastoma by delivering medication and immune cells more effectively to the tumor site.

  Recruiting Northwell Health · New York, New York · NCT05979064

• Support intervention for patients with malignant brain tumors

  This study is testing a support program that gives information and coaching to help people cope with a recent diagnosis of malignant brain tumors.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT05976490

• Detecting microplastics in patients undergoing neurosurgery

  This study is trying to see if tiny pieces of plastic are found in the blood, brain fluid, and brain tissue of patients who are having brain surgery.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT05968053

• Testing a new treatment for brain tumors positive for DLL3

  This study is testing a new treatment for adults with advanced glioma that has the DLL3 marker to see if a special antibody can help their immune system fight the tumor better.

  Recruiting at 10 sites Phase 1 Boehringer Ingelheim · Orange, California and 11 other locations · NCT05916313

• HOPE: Clinical, Pathology, and Imaging Project for Brain Tumors

  This project collects clinical records, MRI scans, and pathology data from people with glioma and other primary brain tumors to build large databases for improving diagnosis and care.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT05859659

• Entrectinib treatment for patients with ROS1-positive cancers

  This study is testing if the drug entrectinib can help people with different types of cancers that have a ROS1 gene fusion, including adults and kids, to see if it works better than what’s currently available.

  Recruiting at 24 sites Phase 2/3 Cancer Research UK · Belfast and 26 other locations · NCT05770544

• Combination of vemurafenib and cobimetinib for treating BRAF positive cancers

  This study is testing if the combination of vemurafenib and cobimetinib can help adults with different types of cancers that have a specific BRAF mutation.

  Recruiting at 16 sites Phase 2/3 Cancer Research UK · Belfast and 15 other locations · NCT05768178

• Impact of Radiotherapy on Neurocognition in Brain Tumor Patients

  This study is testing how radiotherapy affects thinking and memory in adults with brain tumors over time to see if certain treatments lead to cognitive decline.

  Recruiting at 3 sites Universitaire Ziekenhuizen KU Leuven · Ghent and 2 other locations · NCT05727605

• Noninvasive detection of IDH mutations in gliomas using MRI

  This study is trying to see if a special MRI can help find IDH mutations in brain tumors called gliomas to better guide treatment for patients with these tumors.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris and 1 other locations · NCT05700071

• Gene therapy combined with radiotherapy for brain tumors

  This study is testing a new gene therapy combined with targeted radiation to see if it can safely help people with recurrent high-grade brain tumors.

  Recruiting Phase 1 Henry Ford Health System · Detroit, Michigan · NCT05686798

• Investigating genetic and molecular profiles of pediatric brain tumors in China

  This study is trying to understand the genetic makeup of brain tumors in children to see how it affects their treatment and recovery.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT05672043

• Treatment with ONC201 for patients with H3 K27M-mutant diffuse glioma after radiotherapy

  This study is testing if the drug ONC201 can help people with a specific type of brain tumor live longer and stay healthier after they finish their initial radiation treatment.

  Recruiting at 94 sites Phase 3 Jazz Pharmaceuticals · Phoenix, Arizona and 161 other locations · NCT05580562

• Examining cognitive changes in brain tumor patients receiving radiation therapy

  This study is trying to see how radiation therapy affects thinking and memory in people with brain tumors over time, so that doctors can improve treatment and help patients keep their cognitive skills.

  Recruiting University of California, San Diego · San Diego, California · NCT05576103

• Evaluating a new imaging method for low-grade brain tumors in children

  This study is testing a new imaging method to see if it can help doctors better monitor and manage low-grade brain tumors in children.

  Recruiting Early Phase 1 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT05555550

• Using 18F-fluciclovine PET-MRI to assess high-grade gliomas in children

  This study is testing a special imaging technique to see if it can help doctors tell the difference between real tumor growth and changes after treatment in children with high-grade brain tumors.

  Recruiting Early Phase 1 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT05553041

• Comparing in-person and remote monitoring for cancer follow-up

  This study is testing whether patients with rare tumors follow their post-treatment care plans better with in-person visits from a doctor or remote check-ins with a nurse.

  Recruiting Phase 2 Centre Oscar Lambret · Amiens and 2 other locations · NCT05500391

• Registry for patients with NF1-associated glioma

  This study is creating a registry to collect information from people with neurofibromatosis type 1 and glioma to see how the disease and its treatments affect their lives over time.

  Recruiting at 7 sites Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT05489783

• Using ultrasound to guide brain surgery for tumors and lesions

  This study is testing if using ultrasound during brain surgery can help doctors find and remove tumors and lesions more accurately to improve patient outcomes.

  Recruiting Sklifosovsky Institute of Emergency Care · Moscow · NCT05484245

• Calculating brain shift during surgery

  This study is testing a new way to track changes in the brain during surgery to see if it can help doctors perform better and improve results for patients with brain tumors and other brain issues.

  Recruiting Sklifosovsky Institute of Emergency Care · Moscow · NCT05477680

• Using advanced imaging techniques to improve brain cancer diagnosis

  This study is testing a new imaging technique to see if adding special scans can help doctors better diagnose brain cancer in patients getting PET/MRI exams.

  Recruiting Centre Paul Strauss · Strasbourg · NCT05464992

• Evaluating Rhenium-186 NanoLiposomes for Recurrent Glioma Treatment

  This study is testing a new treatment using Rhenium-186 NanoLiposomes to see if it can safely help people with recurrent glioma who have already had this type of therapy.

  Recruiting Phase 1 Cerenome · San Antonio, Texas · NCT05460507

• Investigating tumor mutations in glioma patients using advanced imaging techniques

  This study is trying to see if advanced imaging techniques can help predict how brain tumors called gliomas change over time in patients who are having surgery for their tumors.

  Recruiting Indiana University · Indianapolis, Indiana · NCT05386043

• Combining All-Trans Retinoic Acid and PD-1 Inhibition for Recurrent IDH-Mutant Glioma

  This study is testing if a combination of a vitamin A derivative and a cancer immunotherapy can help people with recurrent IDH-mutant glioma feel better and fight their tumors.

  Recruiting Phase 2 Abramson Cancer Center at Penn Medicine · Philadelphia, Pennsylvania · NCT05345002

• Using electric fields to treat brainstem gliomas

  This study is testing whether wearing a device that uses electric fields along with standard treatments can help people with brainstem gliomas feel better and live longer.

  Recruiting Emory University · Atlanta, Georgia and 2 other locations · NCT05310448

• Safusidenib as maintenance therapy for IDH1‑mutant astrocytoma and oligodendroglioma

  This trial tests whether the oral drug safusidenib can help people with IDH1‑mutant astrocytomas or oligodendrogliomas remain progression‑free longer after surgery and standard radiation/chemotherapy.

  Recruiting at 59 sites Phase 3 Nuvation Bio Inc. · Birmingham, Alabama and 60 other locations · NCT05303519

• Mapping blood vessel characteristics in brain tumors

  This study is testing a new MRI technique to see if it can help doctors understand the blood vessels in brain tumors without needing to do a biopsy.

  Recruiting Leiden University Medical Center · Leiden and 1 other locations · NCT05274919

• Observational assessment of treatment outcomes for patients with primary brain tumors

  This study looks at how well treatments work for people with rare primary brain tumors using new classification guidelines to see if they help doctors group patients better.

  Recruiting at 42 sites European Organisation for Research and Treatment of Cancer - EORTC · Innsbruck and 41 other locations · NCT05259605

• Combination treatment for glioma using pembrolizumab, olaparib, and temozolomide

  This study is testing if a combination of three drugs can help people with glioma that hasn't improved with other treatments or has come back after treatment.

  Recruiting at 10 sites Phase 2 Memorial Sloan Kettering Cancer Center · Hartford, Connecticut and 9 other locations · NCT05188508

• Investigating the role of platelets in brain tumors

  This study looks at how platelets might affect the growth and spread of brain tumors, especially gliomas, by collecting blood and tumor samples to better understand their interactions.

  Recruiting Fondation Ophtalmologique Adolphe de Rothschild · Paris · NCT05049148

• Using tumor infiltrating lymphocytes to treat brain glioma

  This study is testing a new treatment using patients' own immune cells to see if it can help people with aggressive brain tumors that haven't improved with other therapies.

  Recruiting Early Phase 1 Shanghai Juncell Therapeutics · Suzhou, Jiangsu · NCT04943913

• Liquid biopsy for diagnosing glioma tumors

  This study is testing if a simple blood test can help doctors find and understand glioma brain tumors better, making it easier to decide on the right treatment.

  Recruiting Hospices Civils de Lyon · Bron · NCT04931732

• Using advanced MRI to diagnose brain tumors

  This study is testing a new type of MRI to see if it can better identify brain tumors called infiltrating gliomas in patients who are about to have surgery.

  Recruiting Phase 1 University of Maryland, Baltimore · Baltimore, Maryland · NCT04772456

• Using laser therapy and radiation to treat newly diagnosed gliomas

  This study is testing a new treatment that combines laser therapy and radiation to see if it helps people with newly diagnosed brain tumors called gliomas.

  Recruiting at 5 sites University of Maryland, Baltimore · Baltimore, Maryland and 4 other locations · NCT04699773

• Telehealth discussions about end-of-life care for patients with high grade glioma

  This study is trying to see if telehealth visits can help patients with high grade glioma and their families have important conversations about end-of-life care planning.

  Recruiting University of Rochester · Rochester, New York · NCT04543201

• Assessing tissue stiffness in glioma patients using MRE scans

  This study is testing if special scans can measure how stiff brain tissue is in patients with gliomas and radiation damage to see how these conditions differ.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT04373720

• Improving glioma diagnosis and treatment through molecular analysis

  This study is trying to improve how gliomas are diagnosed and treated by looking at the genetic changes in tumors to find better, personalized therapies for patients.

  Recruiting at 11 sites University of Birmingham · Birmingham and 13 other locations · NCT04274283

• Metabolic analysis of brain tumors using advanced MRI techniques

  This study is testing advanced MRI techniques to see if they can help identify specific changes in brain tumors that could improve treatment and survival for patients with gliomas.

  Recruiting Insel Gruppe AG, University Hospital Bern · Bern · NCT04233788

• Using AI to predict molecular pathology in glioma from histopathology images

  This study is trying to see if artificial intelligence can help predict the specific types of gliomas using images of the tumors to improve treatment options for patients.

  Recruiting The First Affiliated Hospital of Zhengzhou University · Zhengzhou, Henan · NCT04217044

• Using AI to predict molecular pathology in glioma patients

  This study is trying to see if using AI can help predict the specific molecular features of gliomas in patients by looking at their MRI scans and other data to improve treatment options.

  Recruiting The First Affiliated Hospital of Zhengzhou University · Zhengzhou, Henan · NCT04217018

• Using AI to predict survival in glioma patients based on histopathology images

  This study is trying to see if using artificial intelligence to analyze tissue images can help doctors predict how long glioma patients might live.

  Recruiting The First Affiliated Hospital of Zhengzhou University · Zhengzhou, Henan · NCT04215224

• Using AI to predict survival in glioma patients

  This study is trying to see if using artificial intelligence can help predict how long people with gliomas might live based on their unique tumor details and medical information.

  Recruiting The First Affiliated Hospital of Zhengzhou University · Zhengzhou, Henan · NCT04215211

• Locoregional immunotherapy using CAR T cells for pediatric brain tumors

  This study is testing a new treatment using specially modified immune cells to see if it can help children and young adults with certain types of brain tumors feel better.

  Recruiting Phase 1 Seattle Children's Hospital · Seattle, Washington · NCT04185038

• Using microdialysis during brain surgery to collect biomarkers for tumors

  This study is testing if a special device used during brain surgery can help doctors collect important information about brain tumors to improve diagnosis and treatment for patients with these conditions.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT04047264

• Analysis of blood tumor markers for cancer diagnosis and treatment monitoring

  This study is testing whether a simple blood test can replace traditional tissue biopsies to help diagnose cancer and monitor how well treatments are working.

  Recruiting at 2 sites Institut du Cancer de Montpellier - Val d'Aurelle · Montpellier and 1 other locations · NCT04025541

• Using hyperpolarized imaging to diagnose glioma

  This study is testing a new type of MRI using a special substance to see if it can help doctors better diagnose glioma in patients who have signs of leftover disease.

  Recruiting Phase 1 University of California, San Francisco · San Francisco, California · NCT03739411

• Using Escitalopram to Improve Cognition in Glioma Patients

  This study is testing if the medication escitalopram can help improve thinking skills and mood in patients with grade IV glioma over 17 weeks.

  Recruiting Phase 2 University of Nebraska · Omaha, Nebraska · NCT03728673

• Non-invasive imaging to characterize gliomas

  This study is testing a new MRI method to see if it can help understand gliomas better by measuring certain substances in the tumor without needing any invasive procedures.

  Recruiting University of Miami · Miami, Florida · NCT03684109

• Comparing seizure treatments in glioma patients

  This study is testing which of two common seizure medications, levetiracetam or valproic acid, works better for people with glioma who have just had their first seizure.

  Recruiting at 4 sites Phase 4 Leiden University Medical Center · Amsterdam and 4 other locations · NCT03048084

• Targeting brain tumors with a specific drug infusion and re-irradiation

  This study is testing a new way to deliver a drug directly to brain tumors in patients with certain aggressive types of glioblastoma to see if it can improve treatment results.

  Recruiting Phase 2 Northwell Health · New York, New York · NCT02800486

• Registry of patients with low grade gliomas

  This study is collecting information from patients with low grade gliomas to see how the disease behaves and what factors might affect treatment and outcomes.

  Recruiting University of Ulm · Ulm · NCT02686229

• Molecular testing for personalized cancer therapy at MD Anderson

  This study is testing if looking at the genetic makeup of tumors in cancer patients can help find the best personalized treatments and match them with suitable clinical trials.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT01772771

• Using advanced MRI to identify high-risk areas in brain tumors for radiation planning

  This study is testing if advanced MRI can help doctors find the most dangerous parts of brain tumors to plan better radiation treatment for patients with malignant gliomas.

  Recruiting Memorial Sloan Kettering Cancer Center · New York, New York · NCT00870129

NIH-funded research (newest 40 of 240)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Next‑gen oncolytic virus therapy for glioblastoma targeting AKT and ERK

  A new cancer therapy using an engineered oncolytic virus to fight glioblastoma by blocking AKT/ERK signals and boosting the body’s immune response, with potential to reduce seizures and improve quality of life.

  NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11578987

• Bone marrow immune cells and glioma progression in teens and young adults

  A study in adolescents and young adults with brain tumors looks at how immune cells from bone marrow may influence the progression from low-grade to high-grade gliomas.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11576103

• How RNA Splicing Might Shape Glioma Cell States and Therapy Response

  A small NIH-funded project will study how alternative RNA splicing influences glioma cell identities and treatment resistance in patient-derived cells.

  NIH research Medical University of South Carolina · Charleston, United States · NIH-11509415

• Liquid biopsy for monitoring high-grade glioma using patient-specific DNA junctions

  A Mayo Clinic team tests a blood test that looks for unique tumor DNA pieces in glioblastoma patients to monitor disease without frequent scans.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11457457

• Deciphering how a brain cell pH helper influences glioma growth

  A study is exploring whether a brain cell pH regulator (Slc4a4) affects the growth and blood vessel changes of malignant glioma to identify new angles for treatment.

  NIH research Virginia Polytechnic Inst and St Univ · Blacksburg, United States · NIH-11457153

• Predicting how gene therapy spreads in glioblastoma after surgery to improve treatment coverage

  This project uses a gene therapy that helps radiation work better against glioblastoma and builds computer models to predict where the therapy reaches after surgical tumor removal.

  NIH research University of Florida · Gainesville, United States · NIH-11453740

• Synergistic blood-brain barrier opening and targeted glioma treatment with pulsed electric fields

  A new approach uses tiny, rapid electric pulses to safely disrupt the brain's protective barrier and enhance targeted treatment for malignant glioma.

  NIH research Georgia Institute of Technology · Atlanta, United States · NIH-11453163

• Canine and human high-grade gliomas: linking dog and human tumor biology to guide better treatments

  A study in dogs with high-grade glioma aims to reveal parallels to human brain tumors so that treatments looked promising in dogs might translate to people.

  NIH research University of California at Davis · Davis, United States · NIH-11449919

• IDH mutation in glioma changes how brain cells talk to tumor cells

  This project looks at how a specific tumor mutation (IDH) changes the nearby brain environment and helps glioma tumors grow.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11449108

• Low-intensity ultrasound to release chemotherapy directly into pediatric brain tumors

  A small grant is exploring a targeted way to open the blood-brain barrier and release chemotherapy right at the tumor site in kids with a dangerous brain tumor.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11442446

• Linking epileptic bursts and tumor growth in IDH-mutant glioma

  This grant explores how seizures and tumor growth influence each other in a specific brain cancer and how understanding this relationship could improve treatment for patients.

  NIH research University of Texas Med Br Galveston · Galveston, United States · NIH-11441993

• Individualized DNA junctions to track glioma with spinal/CSF liquid biopsies

  A Mayo Clinic-led study will test patient-specific DNA junctions in cerebrospinal fluid to monitor glioblastoma and other astrocytic tumors over time.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11428462

• Innate immune memory to help glioblastoma therapy

  A Duke team is testing a weakened poliovirus treatment that could boost the body's immune attack on glioblastoma in patients who have the tumor.

  NIH research Duke University · Durham, United States · NIH-11428036

• Understanding how glioma changes over a patient’s lifetime

  A study to map how glioma tumors change from diagnosis through progression in many patients, to find patterns that could guide better treatments.

  NIH research Yale University · New Haven, United States · NIH-11424804

• OPTIMUM: Engaging LGG patients in understanding how low-grade brain tumors evolve

  A large study plans to involve people with low-grade glioma to map how their tumors change from initial diagnosis to recurrence using patient-friendly data sharing and trial connections.

  NIH research Yale University · New Haven, United States · NIH-11421826

• Diagnostic and predictive tool D2HGlo for glioma patients

  A new liquid biomarker test (D2HGlo) aims to help people with IDH-mutant gliomas by measuring D-2-HG levels to guide treatment decisions.

  NIH research Northern Michigan University · Marquette, United States · NIH-11418321

• Targeted therapies for pediatric low-grade glioma

  A pediatric brain tumor project aims to find better, safer targeted treatments for kids with low-grade gliomas.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11417209

• Targeted Therapies for Pediatric and Young Adult Glioma

  A funded program aims to develop brain-tumor treatments that specifically target genetic drivers in children and young adults with glioma.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11417207

• Diffuse Midline Glioma: Understanding Why Pediatric Brain Tumors Relapse After Radiation

  A researcher team is studying why certain pediatric brain tumors called diffuse midline gliomas resist and come back after radiotherapy, to help develop better treatments.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-11415783

• Bispecific antibodies to help kids fight neuroblastoma and brain tumors

  A pediatric-focused grant tests new bispecific antibodies that help the immune system attack childhood cancers like neuroblastoma and brain tumors.

  NIH research Seattle Children's Hospital · Seattle, United States · NIH-11413442

• Targeting tumor and T cell DNA methylation to boost CAR T therapy for diffuse midline glioma

  A pediatric brain tumor study aims to improve CAR T cell therapy by tweaking DNA methylation in both tumor cells and CAR T cells to make treatments work better.

  NIH research St. Jude Children's Research Hospital · Memphis, United States · NIH-11408774

• Neural stem cells carrying cancer-killing viruses to treat brain cancer

  A study tests delivering a virus that specifically targets brain tumors using neural stem cells to reach cancer cells across the brain.

  NIH research Northwestern University · Chicago, United States · NIH-11402760

• H3K27M ctDNA Test for Tracking Diffuse Midline Glioma

  A minimally invasive blood or CSF test is being developed to detect a specific cancer marker and monitor brain tumor growth in children with DMG.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11401915

• Novel metabolic imaging markers to track IDH-mutant glioma response

  A patient-friendly look at using advanced hyperpolarized carbon imaging to see how IDH-mutant brain tumors respond to treatment.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11399845

• DNA methylation-based blood biomarkers to predict prognosis and treatment response in glioma patients

  A patient-facing summary: researchers will use blood-based DNA methylation markers to help predict how glioma patients might fare and respond to treatments.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11399838

• Epigenetic dependence in DIPG with H3K27M mutation

  This project looks at how DIPG brain cancer cells with the H3K27M mutation rely on other chromatin regulators, which could point to new treatment targets.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11398046

• Germline and tumor genetics to understand glioma risk and patient outcomes

  A Mayo Clinic team will study how inherited and tumor DNA variants relate to glioma risk and how this information could improve care for adults with brain tumors.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11397799

• Mutant IDH glioma: how blocking IDH and DNA damage affects tumor growth

  A patient-friendly look at a grant testing how stopping mutant IDH enzymes and DNA damage pathways could slow or stop certain brain cancers in adults.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11397550

• Ferroptosis in drug resistant glioma

  This project looks at why hard-to-treat brain tumors stop responding to standard chemotherapy and explores a new way to kill resistant cancer cells by triggering a form of cell death called ferroptosis.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11397246

• Targeted study on a pediatric brain cancer subtype with specific gene mutations

  A study to understand why a rare form of high-grade brain cancer in young people develops and to find new treatment targets.

  NIH research University of Georgia · Athens, United States · NIH-11395631

• Improving glioblastoma treatment by targeting tumor inflammation

  This project looks at using a new approach to help brain cancer patients with glioblastoma respond better to immunotherapy by reducing harmful inflammation in the tumor.

  NIH research Beckman Research Institute/city of Hope · Duarte, United States · NIH-11395402

• Self-assembling camptothecin gel for local brain tumor treatment

  A Johns Hopkins-led study is testing a new injectable gel that releases a cancer drug over time to help treat glioblastoma after brain tumor surgery.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11389340

• Targeting brain tumor environment with nano medicines for glioblastoma

  A new treatment approach aims to cross the brain barrier and work with the immune system to slow or stop glioblastoma growth.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11384533

• How IDH Mutations Start Glioma (Brain Tumor)

  This grant looks at how specific genetic changes in IDH genes help start certain brain tumors called gliomas, with research done in a mouse model and advanced cellular analyses.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11384439

• Impact of changing GABA signaling on brain function in glioma-related seizures

  Aims to see if adjusting GABA signaling can reduce seizures and improve brain function in glioma patients, using findings from mouse studies to guide potential treatments.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11380971

• Understanding how diffuse low-grade gliomas disrupt cortical information processing

  This study looks at how a common adult brain tumor changes brain circuits and thinking skills, with the aim of guiding better therapies for cognitive problems.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11379967

• Reprogramming macrophages to fight glioblastoma by targeting glioma stem cells

  Aims to find drugs that reprogram tumor-supporting immune cells in glioblastoma to become tumor-fighting, helping kill cancer stem cells.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11378347

• Combination metabolic therapy for diffuse midline glioma in children

  A pediatric brain cancer study tests a combination metabolic approach to kill DMG tumor cells in kids.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11378158

• Understanding immune responses in IDH-mutant glioma patients treated with ATRA and PD-1 inhibitors

  This grant looks at how the immune system reacts in people with a specific brain cancer when given a retinoic acid and a PD-1 blocker, using both patient data and mice to find clues for better therapies.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11377314

• Targeting abnormal RNA splicing to fight glioma

  This project works on ways to stop glioma cells by fixing or blocking abnormal RNA splicing that helps tumors grow, with the goal of helping people with gliomas.

  NIH research Northwestern University · Chicago, United States · NIH-11375486

Related topics

Quick answers

How many Glioma clinical trials are recruiting right now?

124, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 29 countries. The most sites are in United States (51 trials), China (25 trials), France (11 trials), Italy (10 trials), United Kingdom (7 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 16, Phase 2: 11, Early Phase 1: 7, Phase 1/2: 6. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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