Clinical trial Recruiting at 1 site Observational Ages 1 Year to 90

Using AI to predict survival in glioma patients

Official title: MR Based Survival Prediction of Patients With Primary Glioma Ssing Deep Learning or Machine Learning

Run by The First Affiliated Hospital of Zhengzhou University · NCT04215211 · Data updated 2026-11-12

This study is trying to see if using artificial intelligence can help predict how long people with gliomas might live based on their unique tumor details and medical information.

Quick facts

Study typeObservational
Ages1 Year to 90 Years
SexAll
Enrollment2500 (estimated)
SponsorThe First Affiliated Hospital of Zhengzhou University
Academic / other
Locations1 site (Zhengzhou, Henan)
StatusRecruiting
StartedJanuary 1, 2017
Main results expectedJanuary 1, 2027
Study endsJune 1, 2027
Registry record updatedFebruary 8, 2021
Trial IDNCT04215211 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients with a confirmed diagnosis of primary glioma who are scheduled for tumor resection and have a life expectancy of more than three months.

Probably not a fit

Patients with non-glioma tumors, insufficient tumor tissue for molecular analysis, or those with severe systemic malfunctions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational registry collects clinical, molecular, and radiologic data from patients with primary gliomas to develop artificial intelligence algorithms for predicting survival outcomes. It focuses on integrating advanced MRI sequences and molecular pathology information to enhance the accuracy of survival predictions. By analyzing a large dataset of over 1000 patients, the study aims to provide personalized and non-invasive prognostic insights for glioma patients based on their specific tumor characteristics.

Why it matters

Potential benefit: If successful, this approach could lead to more accurate survival predictions, allowing for better personalized treatment plans for glioma patients.

How similar studies have gone: Other studies utilizing AI for survival prediction in glioma patients have shown promising results, indicating the potential for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients must have radiologically and histologically confirmed diagnosis of primary glioma
* Life expectancy of greater than 3 months
* Must receive tumor resection
* Signed informed consent

Exclusion Criteria:

* No gliomas
* No sufficient amount of tumor tissues for detection of molecular pathology
* Patients who have any type of bioimplant activated by mechanical, electronic, or magnetic devices
* Patients who are pregnant or breast feeding
* Patients who are suffered from severe systematic malfuctions

Where it's running

  • Department of Neurosurgery, First Affiliated Hospital of Zhengzhou University
    Zhengzhou, Henan, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • YN003 injection in glioma patients

    This phase 1 study tests whether YN003 injected IV is safe and tolerable for adults with recurrent or progressive glioma, and to explore how the drug behaves in the body and any early signs of activity.

    Recruiting at 2 sites Phase 1 Beijing Inno Medicine Co., Ltd. · Los Angeles, California and 4 other locations · NCT07929909

  • Brain connectome project in adults with brain glioma undergoing surgery

    This registry collects MRI data and clinical information from adults with glioma to see how brain networks relate to surgery and recovery.

    Recruiting Northwell Health · New York, New York · NCT07927595

  • Proton vs. Photon Radiation for Certain Grade 2–3 Gliomas

    This study tests whether proton therapy can better preserve thinking and memory than photon therapy for adults with IDH-mutated grade 2–3 gliomas who need radiation.

    Recruiting at 2 sites University Hospital, Essen · Essen and 1 other locations · NCT07750457

  • Connectome-guided network planning for brain tumor surgery in eloquent areas

    This study tests whether using patient-specific brain network maps from diffusion MRI can help surgeons plan and guide brain tumor removal in eloquent areas.

    Recruiting ARNAS Civico Di Cristina Benfratelli Hospital · Palermo, PA · NCT07717827

  • AI-powered analysis of brain MRI to help glioma care

    Doctors will use AI to study existing MRI scans and patient data from adults with glioma to see if it can help with non-invasive diagnosis and treatment planning.

    Recruiting Università degli Studi di Trento · Trento · NCT07703761

  • Safusidenib in IDH1-mutant glioma after vorasidenib progression

    This trial tests safusidenib in people with IDH1-mutant glioma who progressed on vorasidenib and did not need immediate chemo or radiation.

    Recruiting at 2 sites Phase 2 Nuvation Bio Inc. · Los Angeles, California and 11 other locations · NCT07703436

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.