Calculating brain shift during surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to calculate the magnitude and type of intraoperative brain shift, which can lead to navigation imprecision during brain surgeries. Surgeons will assess the location of the brain surface and various intracranial structures in real-time during surgery. The collected data will be compared postoperatively with lesion characteristics and patient outcomes to evaluate the possibility of predicting brain shift. The study seeks to improve surgical navigation and outcomes for patients undergoing procedures for brain tumors and other intracranial conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* meningioma
* glioma
* cerebral metastasis of solid tumors of any primary origin
* supratentorial localization
* age 18-80 years
* intraoperative use of optical neuronavigation
* high precision of patient's registration in the navigation system (registration error of 2 mm or less)

Exclusion Criteria:

* technical inability to perform accurate pre-operative registration of the patient's anatomical landmarks in the neuronavigational system
* intraoperative displacement of the reference frame relative to the patient's head during the surgical procedure.

Where it's running

• Sklifosovsky Institute of Emergency Care
  Moscow, Russia Recruiting

Study contacts

• Principal investigator: Alexander Dmitriev, MD — Sklifosovsky Institute of Emergency Care
• Study coordinator: Alexander Dmitriev, MD
• Email: dmitriev@neurosklif.ru
• Phone: +7 (916) 423-54-08

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.