Condition

Meningioma clinical trials and research

• 44Clinical trials
• 10NIH research projects
• 15Countries

Newest Meningioma clinical trials

All recruiting trials (44)

• Combination therapy with IN10018 and dalpiciclib for progressive meningioma

  This phase 1 study tests whether taking IN10018 with dalpiciclib is safe and tolerable in adults with growing meningiomas to see if the combo can help control the tumor.

  Recruiting Phase 1 Capital Medical University · Beijing, Beijing Municipality and 1 other locations · NCT07652762

• JZP3507 (ONC206) for recurrent Grade 2/3 meningioma

  A pill-based therapy (JZP3507) is being tested to see if it can help adults with recurrent grade 2 or 3 meningioma who have not benefited from standard treatments.

  Recruiting at 6 sites Phase 2 Jazz Pharmaceuticals · San Francisco, California and 7 other locations · NCT07533942

• Panitumumab-IRDye800 for guiding brain tumor surgery

  A tiny dose of panitumumab-IRDye800 is tested to see if it helps visualize brain tumors during surgery in adults.

  Recruiting Early Phase 1 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT07493447

• Zanzalintinib for recurrent or progressive meningioma

  This trial tests whether zanzalintinib can help people whose meningioma has come back or kept growing after standard treatments.

  Recruiting at 20 sites Phase 2 Exelixis · Birmingham, Alabama and 19 other locations · NCT07428616

• Meningioma: How social factors and personal risks relate to health outcomes

  This study tests whether social and personal risk factors help explain differences in health outcomes for adults with meningioma.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07418775

• Skin closure after brain tumor surgery: running absorbable versus interrupted non-absorbable sutures

  This will test whether absorbable running intradermal sutures or non-absorbable interrupted transdermal sutures produce better wound healing after craniotomy in adults with supratentorial brain tumors.

  Recruiting Medical University of Warsaw · Warsaw, Masovian Voivodeship · NCT07413796

• Cerebrospinal fluid leak after brain tumor surgery

  This project will look at adults having planned supratentorial craniotomy for intracranial tumors to see how often cerebrospinal fluid leaks occur and what complications they cause.

  Recruiting Medical University of Warsaw · Warsaw · NCT07411690

• Blood or CSF test for circulating tumor cells in aggressive meningioma recurrences

  This study tests whether circulating tumor cells can be found in the blood or cerebrospinal fluid of adults with aggressive, recurrent meningiomas after surgery.

  Recruiting University Hospital, Montpellier · Montpellier, France · NCT07398170

• Translate and validate the MQOL quality-of-life questionnaire into French for people with meningioma

  This project will translate the MQOL quality-of-life questionnaire into French and try it with adults who have intracranial meningioma to see if it works well in French.

  Recruiting Centre Hospitalier St Anne · Paris · NCT07044076

• Evaluating meningioma properties using 3D magnetic resonance elastography

  This study is testing if a new type of MRI can help doctors understand the stiffness and attachment of meningiomas in patients before surgery to improve planning and safety.

  Recruiting Shengjing Hospital · Shenyang, Liaoning · NCT06955208

• Home-based self-management and cognitive training for brain tumor survivors

  This trial will try a home-based cognitive coaching program to see if it improves thinking and quality of life for adults who survived non-glioblastoma brain tumors, with optional caregiver participation.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06930846

• Investigating the effects of endoscopic skull base surgery on smell

  This study tests how endoscopic skull base surgery affects the sense of smell in patients to better understand any smell-related problems that might happen after the surgery.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven, Vlaams-Brabant and 2 other locations · NCT06874426

• Proton versus photon radiation for adults with primary brain tumors

  This trial will test whether proton beam radiation causes fewer long-term side effects than standard photon (X-ray) radiation in adults aged 18–70 with primary brain tumors who are expected to live more than five years.

  Recruiting Tata Memorial Centre · Mumbai · NCT06831461

• Using PET imaging to improve radiation therapy for high-risk meningiomas

  This study is testing if using special PET scans to guide higher doses of radiation therapy can help men with high-risk meningiomas live longer without their cancer getting worse.

  Recruiting Centro di Riferimento Oncologico - Aviano · Aviano, Pordenone · NCT06830356

• Pharmacoscopy-guided treatment for refractory brain tumors

  This trial tests whether personalized drug testing on a patient’s tumor cells can guide treatment choices for adults with hard-to-treat brain cancers like glioblastoma.

  Recruiting Phase 2 University of Zurich · Basel, Basel-Landschaft and 2 other locations · NCT06804655

• Robot-assisted procedures for neurovascular conditions

  This study is testing whether using robots to help with brain and blood vessel procedures can make them safer and more effective for patients.

  Recruiting Navigantis Inc. · Seoul, Korea · NCT06752096

• Effects of Salovum® and SPC® Flakes on Brain Tumor Edema

  This study is testing if eating Salovum® and SPC® flakes can help reduce swelling in the brain and improve symptoms for people with certain types of brain tumors.

  Recruiting Phase 2 Skane University Hospital · Lund · NCT06710249

• Imaging brain tumors using a targeted radioimmunoconjugate and PET scans

  This study is testing a new imaging method using a special drug to see if it can help identify immune cells in patients with brain tumors before they have surgery.

  Recruiting Phase 1 Jonsson Comprehensive Cancer Center · Los Angeles, California · NCT06650163

• Combining TIL Therapy and Pembrolizumab for Advanced Brain Cancer

  This study is testing a new treatment that combines a type of immune therapy using patients' own tumor cells with Pembrolizumab to see if it helps people with advanced brain cancer feel better and live longer.

  Recruiting Phase 1/2 Essen Biotech · Beijing, Beijing Municipality · NCT06640582

• Combining Lutathera® and Olaparib for treating recurrent solid tumors in children and adolescents

  This study is testing if combining Lutathera® with olaparib can help children and teenagers with hard-to-treat solid tumors that have certain receptors.

  Recruiting Phase 1/2 Fundación de investigación HM · Boadilla del Monte, Madrid · NCT06607692

• Hypofractionated Stereotactic Radiosurgery for Intermediate-risk Meningioma

  This study is testing a new way of giving radiation therapy over five days to see if it helps people with certain types of brain tumors feel better and have a better quality of life after treatment.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06557512

• Using a special imaging agent to detect meningioma during surgery

  This study is testing a special imaging agent to see if it can help doctors find meningioma tumors during surgery for patients who are having them removed.

  Recruiting Phase 4 Weill Medical College of Cornell University · New York, New York · NCT06377371

• Dexamethasone dosing after brain tumor surgery

  This study is testing if a lower dose of dexamethasone after brain tumor surgery can help reduce side effects for patients compared to the usual dose.

  Recruiting Phase 2 Emory University · Atlanta, Georgia · NCT06132685

• Combining Everolimus and 177Lu-DOTATATE for treating refractory meningioma

  This study is testing if combining two treatments, Everolimus and 177Lu-DOTATATE, can help adults with hard-to-treat meningioma tumors live longer without their cancer getting worse.

  Recruiting Phase 2 Central Hospital, Nancy, France · Vandœuvre-lès-Nancy, Grand Est and 1 other locations · NCT06126588

• Investigating blood markers in meningioma patients undergoing radiotherapy

  This study is testing if certain blood markers can help doctors understand how meningioma tumors respond to radiotherapy in patients receiving treatment.

  Recruiting University Hospital Heidelberg · Heidelberg · NCT06104930

• Impact of different radiation therapies on cognitive function in meningioma patients

  This study is testing how different types of radiation therapy affect thinking and memory in patients with certain brain tumors.

  Recruiting Centre Francois Baclesse · Caen and 2 other locations · NCT06036706

• Using hyperpolarized imaging to evaluate meningioma tumors

  This study is testing a new imaging method using a special substance to see if it can help doctors better understand the behavior of aggressive meningioma tumors in patients before surgery.

  Recruiting Phase 1 University of California, San Francisco · San Francisco, California · NCT06014905

• Using abemaciclib to treat newly diagnosed meningioma patients

  This study is testing if the drug abemaciclib can help men with newly diagnosed grade 3 meningioma after they have surgery and radiation therapy.

  Recruiting Phase 2 St. Joseph's Hospital and Medical Center, Phoenix · Phoenix, Arizona · NCT05940493

• Identifying factors that predict survival in aggressive meningiomas

  This study is trying to find out what factors can help predict how long patients with aggressive meningiomas will survive after surgery.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Rome · NCT05793034

• Impact of Radiotherapy on Neurocognition in Brain Tumor Patients

  This study is testing how radiotherapy affects thinking and memory in adults with brain tumors over time to see if certain treatments lead to cognitive decline.

  Recruiting at 3 sites Universitaire Ziekenhuizen KU Leuven · Ghent and 2 other locations · NCT05727605

• Targeted Alpha-Particle Therapy for Advanced SSTR2 Positive Neuroendocrine Tumors

  This study is testing a new type of treatment using targeted alpha-particle therapy to see if it can help people with advanced neuroendocrine tumors that have a specific protein called SSTR2.

  Recruiting at 20 sites Phase 1/2 Perspective Therapeutics · Jacksonville, Florida and 19 other locations · NCT05636618

• Examining cognitive changes in brain tumor patients receiving radiation therapy

  This study is trying to see how radiation therapy affects thinking and memory in people with brain tumors over time, so that doctors can improve treatment and help patients keep their cognitive skills.

  Recruiting University of California, San Diego · San Diego, California · NCT05576103

• Using Cabozantinib to treat recurrent or progressive meningioma

  This study is testing if Cabozantinib can help people with recurring or worsening meningioma, a type of brain tumor, feel better after other treatments haven’t worked.

  Recruiting at 3 sites Phase 2 Baptist Health South Florida · Miami, Florida and 2 other locations · NCT05425004

• Embolization treatment for meningioma

  This study is testing a new way to treat meningioma brain tumors using a method that could help reduce bleeding during surgery and improve outcomes for patients.

  Recruiting St. Olavs Hospital · Trondheim · NCT05416567

• Lutathera treatment for recurrent high-grade brain tumors

  This study is testing if Lutathera can safely help children and young adults with recurring high-grade brain tumors that show certain markers on scans.

  Recruiting at 2 sites Phase 1/2 Nationwide Children's Hospital · Aurora, Colorado and 3 other locations · NCT05278208

• Observing the growth of non-malignant brain tumors

  This study looks at how non-cancerous brain tumors grow over time in patients who don't have symptoms and aren't needing treatment, using regular MRI scans to track changes.

  Recruiting Seoul National University Hospital · Seoul · NCT05254197

• Evaluating the CONVIVO System for Brain Tumor Surgery

  This study is testing a new imaging tool during brain tumor surgery to see if it can better tell the difference between healthy and unhealthy brain tissue for patients with brain tumors.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT05139277

• Treatment for recurrent or progressive meningiomas using a new radiolabelled somatostatin antagonist

  This study is testing a new treatment using a special type of radiation to see if it can help people with recurring or worsening meningiomas feel better compared to a standard treatment.

  Recruiting Phase 1/2 University Hospital, Basel, Switzerland · Basel, Canton of Basel-City · NCT04997317

• Proton therapy for brain tumors

  This study is testing whether proton therapy can be a better treatment option for patients with certain brain tumors by comparing it to traditional radiation methods to see if it can reduce harm to healthy tissues.

  Recruiting at 3 sites Maastricht Radiation Oncology · Maastricht, Limburg and 2 other locations · NCT04648462

• Assessing cognitive outcomes after skull base meningioma surgery

  This study is testing how surgery for removing skull base meningiomas affects thinking and memory in patients over time.

  Recruiting Ohio State University · Columbus, Ohio · NCT04635657

• Targeted therapies for tumors from NF2-related schwannomatosis

  This platform tests several targeted drug regimens to see if they can slow or shrink progressive NF2-related tumors (vestibular and non-vestibular schwannomas, meningiomas, and ependymomas) in people with NF2-related schwannomatosis.

  Recruiting at 5 sites Phase 2 Massachusetts General Hospital · Los Angeles, California and 5 other locations · NCT04374305

• Database for patients treated with metabolic radiotherapy

  This study is creating a database to collect information and samples from patients with thyroid, prostate, and neuroendocrine tumors who are receiving targeted radiation therapy, to see how it works and improve treatment.

  Recruiting at 3 sites Institut du Cancer de Montpellier - Val d'Aurelle · Bordeaux, Aquitaine and 3 other locations · NCT04104529

• Using 68-Ga DOTATATE PET/MRI to Diagnose and Manage Certain Brain Tumors

  This study is testing if a special type of imaging called 68Ga-DOTATATE PET/MRI can help doctors better diagnose and manage certain brain tumors, especially meningiomas, by telling the difference between tumor recurrence and changes after treatment.

  Recruiting Phase 4 Weill Medical College of Cornell University · New York, New York · NCT04081701

• Developing a liquid biopsy protocol for cancer research at Princess Margaret

  This study is trying to create a simple way to collect blood samples from cancer patients to see if analyzing certain molecules in their blood can help doctors understand their cancer better and track how it changes over time.

  Recruiting University Health Network, Toronto · Toronto, Ontario · NCT03702309

NIH-funded research (10)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Meningioma biology and new therapies guided by molecular profiling

  A large, multi-institution study is exploring how meningiomas grow and respond to treatment, using advanced molecular profiling to find safer, more effective ways to manage them.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11413786

• Biomarker-based guidance to predict meningioma outcomes and radiotherapy response

  A gene-based test is being developed to help predict how meningioma tumors will behave and how patients may respond to radiotherapy.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11394565

• Meningioma radiotherapy response: understanding gene clues and how to tailor treatment

  A short research project will study why some meningioma tumors respond differently to radiotherapy by looking at gene activity and how it affects treatment outcomes.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11379985

• Genomic and biochemical clues behind meningioma race differences and outcomes

  This grant aims to uncover biological and environmental factors that cause differences in meningioma occurrence and treatment results across racial groups, with the goal of improving care for patients affected by this brain tumor.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11378043

• How the MN1 protein drives aggressive acute myeloid leukemia

  This project looks at how the MN1 protein and its partner BAF complex keep leukemia genes active in people with acute myeloid leukemia to reveal new treatment targets.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11305301

• How meningiomas change over time and new treatment targets

  This project looks for molecular signs that predict which meningiomas will come back and finds drug targets to help people with aggressive or recurrent tumors.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11192771

• Finding new ways to treat meningioma brain tumors

  This project looks for new medicine targets to help patients with meningioma, a common type of brain tumor.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11139406

• Investigating how a protein called Meningioma-1 contributes to aggressive leukemia.

  This study is looking at a protein called MN1 to see how it affects blood cells in people with acute myeloid leukemia (AML), with the hope of finding new treatment options for those who aren't responding well to current therapies.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11061004

• Understanding how chromosomal instability affects radiation sensitivity in meningioma tumors

  This study is looking at how a new test can help doctors figure out which patients with meningiomas, a common type of brain tumor, might do better with radiation therapy after surgery, so they can improve treatment options for those who need it.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11036124

• Investigating the causes of meningioma tumors and potential treatments

  This study is looking at how meningioma brain tumors work, especially in older adults and African Americans, to find new ways to treat them with targeted drugs.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-10892127

Related topics

Quick answers

How many Meningioma clinical trials are recruiting right now?

44, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 15 countries. The most sites are in United States (19 trials), France (5 trials), China (3 trials), Italy (2 trials), Belgium (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 9, Phase 1/2: 5, Phase 1: 3, Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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