Investigating the role of platelets in brain tumors
Official title: Observation of Platelets in Primary and Secondary Tumors of the Central Nervous System and Association With Survival: a Prospective Cohort Study
Run by Fondation Ophtalmologique Adolphe de Rothschild · NCT05049148 · Data updated 2026-11-12
This study looks at how platelets might affect the growth and spread of brain tumors, especially gliomas, by collecting blood and tumor samples to better understand their interactions.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Fondation Ophtalmologique Adolphe de Rothschild Research network |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Paris) |
| Status | Recruiting |
| Started | October 27, 2022 |
| Main results expected | October 2026 |
| Study ends | October 2029 |
| Registry record updated | January 5, 2026 |
| Trial ID | NCT05049148 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old who are scheduled for excision or biopsy of a brain or medullary tumor.
✕Probably not a fit
Patients with insufficient tumor sample volume for analysis or those under legal protection measures may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study examines the role of platelets in the progression of brain neoplasms, particularly gliomas. It focuses on understanding how platelets may influence tumor behavior, including metastasis and angiogenesis, through the collection of tumor tissue and blood samples. The research aims to clarify the interactions between platelets and tumor cells in solid tumors, contributing to the broader understanding of cancer biology. The study does not involve any therapeutic interventions but rather observational data collection.
Why it matters
Potential benefit: If successful, this research could lead to new insights into the mechanisms of tumor progression and potential therapeutic targets for glioma treatment.
How similar studies have gone: While the role of platelets in cancer has been studied, this specific investigation into their function in brain tumors is relatively novel and not extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient to undergo excision or biopsy of a brain or medullary tumor * Patient over 18 years old * Express consent to participate in the study * Affiliate member of the Social Security system Exclusion Criteria: * Tumor sample volume not allowing the performance of additional analyzes * Patient benefiting from a legal protection measure * Pregnant or breastfeeding woman
Where it's running
-
Fondation A De Rothschild
Paris, France Recruiting
Study contacts
- Principal investigator: Pierre BOURDILLON, MD — Fondation A. de Rothschild
- Study coordinator: Amélie YACHITZ, MD
- Email: ayavchitz@for.paris
- Phone: (0)148036454
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.