Using ultrasound to guide brain surgery for tumors and lesions
Sonography-guided Resection of Brain Mass Lesions: a Prospective, Single Arm Clinical Trial
This study is testing if using ultrasound during brain surgery can help doctors find and remove tumors and lesions more accurately to improve patient outcomes.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | Sklifosovsky Institute of Emergency Care Government |
| Locations | 1 site (Moscow) |
| Trial ID | NCT05484245 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of intraoperative sonography in detecting various brain mass lesions, such as tumors and vascular malformations, during surgery. The approach involves using ultrasound to assess the extent of lesion resection in real-time, which can enhance surgical precision. The study will utilize novel techniques, including ultrasound-guided needles and ports, to facilitate access to challenging lesions. By integrating ultrasound into the surgical workflow, the study seeks to improve outcomes for patients undergoing brain surgery.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18-100 with newly diagnosed intracranial tumors, cavernomas, arteriovenous malformations, or spontaneous and traumatic intracerebral hemorrhages.
Not a fit: Patients with rapid cerebral dislocation or those who have previously undergone brain radiotherapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more precise surgical resections and better outcomes for patients with brain lesions.
How similar studies have performed: While some studies have explored the use of intraoperative sonography in neurooncology, this specific application and methodology may offer novel insights and improvements.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * all intracranial tumors * cavernomas * arteriovenous malformations * spontaneous (non-traumatic) intracerebral hemorrhages * traumatic intracerebral hemorrhages * supratentorial localization * newly diagnosed * age 18-100 years * stable hemodynamics Exclusion Criteria: * rapid cerebral dislocation * previously performed brain radiotherapy
Where this trial is running
Moscow
- Sklifosovsky Institute of Emergency Care — Moscow, Russia (Recruiting)
Study contacts
- Principal investigator: Alexander Dmitriev, MD — Sklifosovsky Institute of Emergency Care
- Study coordinator: Alexander Dmitriev, MD
- Email: dmitriev@neurosklif.ru
- Phone: +7 (916) 423-54-08
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.