Non-invasive imaging to characterize gliomas

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot study focuses on developing and optimizing MRI-based sequences to non-invasively quantify the distribution of 2-hydroxyglutarate (2HG) and tumor cellularity in gliomas. By using a 3T MRI scanner, the study aims to enhance the understanding of glioma biology and potentially guide the development of new therapies. The approach seeks to provide critical insights without the need for invasive procedures, thereby improving patient care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults (≥18 year old)
* Subjects with suspected or confirmed gliomas and who will have a medically indicated biopsy or resection of his/her brain lesion.

Exclusion Criteria:

* Adults unable to consent
* Individuals who are not yet adults (infants, children, teenagers)
* Pregnant women
* Patients unable to have MRI done

Where it's running

• University of Miami
  Miami, Florida, United States Recruiting

Study contacts

• Principal investigator: Macarena De La Fuente, MD — University of Miami
• Study coordinator: Nathalie Padron
• Email: npadron@med.miami.edu
• Phone: 305-243-3530

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Home-based self-management and cognitive training for brain tumor survivors

  This trial will try a home-based cognitive coaching program to see if it improves thinking and quality of life for adults who survived non-glioblastoma brain tumors, with optional caregiver participation.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06930846

• Combining TIL Therapy and Pembrolizumab for Advanced Brain Cancer

  This study is testing a new treatment that combines a type of immune therapy using patients' own tumor cells with Pembrolizumab to see if it helps people with advanced brain cancer feel better and live longer.

  Recruiting Phase 1/2 Essen Biotech · Beijing, Beijing Municipality · NCT06640582

• Evaluating Bevacizumab with Focused Ultrasound for Recurrent Glioblastoma

  This study is testing if adding focused ultrasound to the standard treatment of Bevacizumab can help people with recurrent glioblastoma feel better and live longer.

  Recruiting at 2 sites Phase 3 NaviFUS Corporation · Taipei and 1 other locations · NCT06496971

• Using MRI to Differentiate Between Brain Tumors and Radiation Effects

  This study is testing a new MRI technique to see if it can help tell the difference between brain tumors and radiation damage in people who have had radiation therapy.

  Recruiting at 2 sites Case Comprehensive Cancer Center · Cleveland, Ohio and 1 other locations · NCT06101069

• Detecting microplastics in patients undergoing neurosurgery

  This study is trying to see if tiny pieces of plastic are found in the blood, brain fluid, and brain tissue of patients who are having brain surgery.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT05968053

• HOPE: Clinical, Pathology, and Imaging Project for Brain Tumors

  This project collects clinical records, MRI scans, and pathology data from people with glioma and other primary brain tumors to build large databases for improving diagnosis and care.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT05859659

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.