Exploring tumor stiffness and adhesion in gliomas using magnetic resonance elastography

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the relationship between tumor stiffness and adhesion in gliomas through the use of Magnetic Resonance Elastography (MRE). By employing preoperative MRE and intraoperative neuronavigation, the research aims to correlate tumor mechanical properties with molecular and genetic characteristics. Comprehensive molecular pathology analysis will follow tissue sample collection during surgery. The goal is to enhance clinical decision-making and personalize treatment approaches for glioma patients based on the findings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. age older than 18 years
2. Karnofsky performance status higher than 60
3. with written informed consent
4. MRE performed within one week before surgery
5. tumor diameter \> 2 cm

Exclusion Criteria:

1. previous treatment for glioma
2. inability to complete MRE due to intolerance (e.g., vibration-related discomfort or claustrophobia)
3. completed MRE with suboptimal wave image quality (e.g., motion artifacts or inad-equate wave amplitude)
4. failure to proceed with surgery after MRE
5. missing IDH results

Where it's running

• Shengjing Hospital
  Shenyang, Liaoning, China Recruiting

Study contacts

• Principal investigator: Yu Shi, MD — Shengjing Hospital
• Study coordinator: Yu Shi, MD
• Email: 18940259980@163.com
• Phone: +86 189 4025 9980

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.