Comparing in-person and remote monitoring for cancer follow-up

Randomized Phase II Trial Evaluating Compliance With Monitoring Conducted Either by a Hospital-based Physician in Person or by a Nurse in Remote Monitoring

Phase 2 Interventional Centre Oscar Lambret · NCT05500391

This study is testing whether patients with rare tumors follow their post-treatment care plans better with in-person visits from a doctor or remote check-ins with a nurse.

Quick facts

PhasePhase 2
Study typeInterventional
Enrollment88 (estimated)
Ages18 Years and up
SexAll
SponsorCentre Oscar Lambret Academic / other
Drugs / interventionschemotherapy
Locations3 sites (Amiens and 2 other locations)
Trial IDNCT05500391 on ClinicalTrials.gov

What this trial studies

This multicenter, interventional study aims to evaluate compliance with personalized post-treatment surveillance plans for patients diagnosed with rare tumors within the last 12 months. Participants will be randomly assigned to receive follow-up care either in person by a physician or remotely by a trained nurse. The primary objective is to compare 2-year compliance rates between the two groups, while secondary objectives include long-term compliance, care utilization, and management of oncological events. Exploratory objectives will assess costs, patient satisfaction, psychological well-being, and reasons for recruitment failures.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who have been diagnosed with specific rare tumors within the last 12 months.

Not a fit: Patients who are unable to undergo the required imaging tests or do not have access to telemedicine may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance patient compliance with follow-up care, potentially improving outcomes for those with rare tumors.

How similar studies have performed: Other studies have shown promise in remote monitoring approaches, but this specific comparison of in-person versus remote follow-up in this context is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Positive diagnosis (anatomopathology) of tumor within 12 months
* Patient 18 years of age or older
* Patient with one of the following conditions:

  1. Desmoid fibromatosis of the abdominal wall operated on or under active surveillance
  2. Stage I testicular seminoma (whether or not treated with carboplatin AUC7)
  3. Stage I non-seminomatous germ cell tumor (with or without adjuvant BEP chemotherapy)
  4. Operated GIST with low risk of relapse
  5. Rare gynecological tumors (sex cord and stromal tumors; germ cell tumors of the ovary, clear cell adenocarcinoma, mucinous adenocarcinoma of the ovary, borderline tumors, small cell carcinoma, ovarian and uterine carcinosarcoma, low grade serous tumors), operated
  6. Low-grade glioma, operated
  7. Low-grade neuroendocrine tumor, treated by surgery alone
* Patient who has given consent to participate in the study

Exclusion Criteria:

* Contraindication to imaging tests required for the surveillance plan
* No telephone
* Patient under guardianship or curatorship

Where this trial is running

Amiens and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Stage I Testicular SeminomaStage I Testicular Nonseminomatous Germ Cell TumorGastrointestinal Stromal TumorsOvarian Germ Cell TumorAdenocarcinoma, Clear CellBorderline Ovarian TumorSex Cord-Stromal TumorMucinous Adenocarcinoma of Ovary
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.