Understanding brain blood flow and metabolism in patients with brain lesions

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research investigates neurovascular uncoupling (NVU) in patients with brain lesions, particularly focusing on glioblastoma, glioma, and astrocytoma. Using a multimodal noninvasive imaging approach, including functional MRI and PET scans, the study aims to explore the mechanisms behind the relationship between brain metabolism, blood flow, and neuronal activity. By analyzing these interactions, the study seeks to improve the understanding of brain function in the context of brain tumors and their treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* patients in the study include prior imaging showing a potentially resectable intra-cerebral mass lesion. Patient has to be included before surgery, chemotherapy and radiation

Exclusion Criteria:

* previous brain surgery
* respiratory failure
* Asthma
* Claustrophobia
* Previous adverse reaction to gadovist (contrast agent)
* Pregnancy and Breath feeding
* Diabetes (type I and II)

Where it's running

• HUB-Erasme Hospital
  Brussels, Belgium Recruiting

Study contacts

• Study coordinator: Thibault Vanbutsele
• Email: thibault.vanbutsele@hubruxelles.be
• Phone: 25558167

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.