Liquid biopsy for diagnosing glioma tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on the use of liquid biopsy to detect glioma-specific oncogenic processes in peripheral blood, particularly through the analysis of circulating tumor DNA (ctDNA). Gliomas are the most common primary brain tumors, and their diagnosis is crucial for effective patient management. The study aims to refine glioma diagnosis by identifying molecular biomarkers that can aid in differentiating tumor grades and guiding treatment decisions. By utilizing liquid biopsy, the study seeks to establish a routine clinical testing method for gliomas, which currently lacks standardized approaches.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patient
* Obtainment of written informed consent
* Suspected newly or recurrent glioma (grade ≥ II) on MRI
* Patient eligible for surgery (biopsy or resection)
* Decision of surgery (biopsy or resection) at neuro-oncology interdisciplinary tumor board

Exclusion Criteria:

* Rejection of consent by patient
* Hemoglobin \< 7g/dl
* Rejection of surgery by patient
* Suspected grade I tumor on MRI

Where it's running

• East Group Hospital, Hospices Civils de Lyon
  Bron, France Recruiting

Study contacts

• Study coordinator: GARNIER Louis, Dr
• Email: louis.garnier@chu-lyon.fr
• Phone: +33 (0)4 72 68 13 59

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Safusidenib in IDH1-mutant glioma after vorasidenib progression

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  Recruiting at 2 sites Phase 2 Nuvation Bio Inc. · Los Angeles, California and 11 other locations · NCT07703436

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.