Condition

Cardiac Surgery clinical trials and research

• 59Clinical trials
• 38NIH research projects
• 2New in 30 days
• 26Countries

Newest Cardiac Surgery clinical trials

All recruiting trials (59)

• Impact of Fast-Track Anesthesia on Postoperative Delirium After Cardiac Surgery

  This observational study tests whether fast-track anesthesia, compared with conventional care, is linked to lower rates of delirium after elective cardiac surgery in adults.

  Recruiting Second Affiliated Hospital of Nanchang University · Nanchang, Jiangxi · NCT07923344

• Sarcopenia in Patients After Cardiac Surgery

  This observational study tests how common sarcopenia is after cardiac surgery and whether current care helps improve muscle mass and function.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven · NCT07908472

• Preoperative functional optimization for adults undergoing major cardiac or abdominal surgery

  This study tests a four‑week prehabilitation program to improve fitness before elective major cardiac or abdominal surgery.

  Recruiting ASST Sette Laghi · Varese, VA and 1 other locations · NCT07851350

• Oral Extubation Right After Cardiac Surgery

  This trial tests whether waking patients and removing the breathing tube in the operating room after elective cardiac surgery helps recovery more quickly without added risk.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts and 1 other locations · NCT07757880

• Frailty and Ultrasound-Guided Catheterization in Adult Cardiac Surgery Patients

  This study tests whether frailty and ultrasound measurements taken before surgery can predict how difficult it will be to place an ultrasound-guided internal jugular venous catheter in adults undergoing elective cardiac surgery.

  Recruiting Ankara City Hospital Bilkent · Ankara, Ankara · NCT07701538

• Prehabilitation before heart surgery for adults with congenital heart disease

  This study is testing whether a tailored, supervised exercise program before heart surgery helps adults with congenital heart disease perform better and improve fitness.

  Recruiting Liverpool Heart and Chest Hospital NHS Foundation Trust · Liverpool · NCT07700459

• Appropriateness of Hemostatic Agent Use in Cardiovascular Surgery

  This study tests how well surgeons’ choices about topical hemostatic agents match current guidelines in cardiac and vascular surgery at one Milan hospital.

  Recruiting University of Milan · Milan, MI · NCT07699016

• Integrated intraoperative hemodynamic monitoring during cardiac surgery with CPB

  This pilot study tests a single-dashboard monitoring system to see if it can capture heart and tissue perfusion data during elective cardiac surgery with bypass in adults without changing patient care.

  Recruiting Hernán Darío Castro Arias MD MSc · Medellín, Antioquia · NCT07683299

• Frailty score predicts quality of life after emergency heart surgery in people 75 and older

  This study tests whether a preoperative frailty score can predict quality of life one year after emergency heart surgery in patients aged 75 and up.

  Recruiting University Hospital, Bordeaux · Bordeaux, France · NCT07677319

• Chronic Postoperative Pain after Cardiac Surgery: Incidence and Impact

  This survey checks how often people have chronic pain 3 months after cardiac surgery and who it affects most, to see if the rate is lower than 33%.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven, Vlaams Brabant · NCT07640646

• Impact of cardiopulmonary bypass on platelet lipids and bleeding after cardiac surgery

  This study tests how CPB changes platelet lipid metabolism and procoagulant platelets to see if these changes relate to inflammation and bleeding after cardiac surgery.

  Recruiting Université Catholique de Louvain · Brussels · NCT07630987

• Upper extremity exercises with and without deep breathing after cardiac surgery

  This study tests whether doing upper body range of motion exercises with deep breathing helps lung function more than the same exercises without deep breathing in adults after open-heart surgery.

  Recruiting Kocaeli University · İzmit, Kocaeli · NCT07627009

• Care after heart surgery: understanding post-discharge needs

  This study looks at what care helps people stay well after heart surgery and who should get what support, by talking with patients and families about experiences since discharge.

  Recruiting University Hospitals Bristol and Weston NHS Foundation Trust · Bristol, Bristol · NCT07611045

• Transcutaneous auricular vagus nerve stimulation to prevent kidney injury after heart surgery

  This trial tests whether applying a non-invasive ear stimulation (taVNS) around the time of elective heart surgery can help prevent acute kidney injury in adults undergoing cardiopulmonary bypass.

  Recruiting Sir Run Run Shaw Hospital · Hangzhou, Zhejiang · NCT07549243

• Ultra fast‑track versus fast‑track anesthesia after off‑pump and minimally invasive valve heart surgery

  This will test whether an ultra fast‑track anesthesia approach helps adults having elective off‑pump or minimally invasive valve heart surgery get extubated sooner and leave the ICU and hospital earlier than standard fast‑track anesthesia.

  Recruiting Azienda Socio Sanitaria Territoriale Ovest Milanese, Ospedale di Legnano · Legnano, Italy · NCT07518524

• Comparing a single erector spinae block to parasternal plus serratus blocks for pain after sternotomy

  We will see if a single erector spinae nerve block or a combination of superficial parasternal and serratus anterior blocks better controls pain and reduces opioid use in adults having elective open‑chest (sternotomy) heart surgery.

  Recruiting Uludag University · Bursa, Nilüfer · NCT07472296

• Fluid choice during heart surgery: comparing HES to crystalloids

  This trial tests whether hydroxyethyl starch helps manage fluids during heart surgery without causing more kidney problems compared with balanced crystalloids.

  Recruiting at 4 sites Phase 4 Seoul National University Hospital · Daejeon and 3 other locations · NCT07410988

• Dexcom G7 glucose monitor accuracy in cardiac surgery patients

  This study tests whether the Dexcom G7 continuous glucose monitor provides accurate readings for adults undergoing cardiac surgery.

  Recruiting Seoul National University Hospital · Seoul · NCT07385170

• Eurosets arterial and venous cannulas for cardiopulmonary bypass procedures

  This trial will test Eurosets arterial and venous cannulas during cardiopulmonary bypass in adults having elective coronary or aortic valve surgery to see if they are as safe and work as well as Medtronic cannulas.

  Recruiting Eurosets S.r.l. · Bari, BA · NCT07354841

• Venous congestion and delirium after heart surgery

  This project will see if venous congestion during and after elective heart surgery is linked to a higher risk of postoperative delirium in adults who can complete cognitive testing.

  Recruiting Yangzhou University · Yangzhou, Jiangsu · NCT07285187

• Personalized lung volume optimization with PEEP titration for children after heart surgery or with severe respiratory failure

  This trial tests whether a personalized lung volume optimization maneuver using PEEP titration can improve heart and lung function in children after cardiopulmonary bypass surgery or in those with severe respiratory failure at risk for ECMO.

  Recruiting Phase 1/2 Charite University, Berlin, Germany · Tübingen · NCT07193719

• Bilateral serratus posterior superior intercostal plane block for pain after on‑pump open‑heart surgery

  This trial will test whether a bilateral serratus posterior superior intercostal plane (SPSIP) block can reduce acute postoperative pain and opioid use in adults having on‑pump open‑heart surgery.

  Recruiting Ondokuz Mayıs University · Samsun · NCT07164677

• Desflurane versus propofol anesthesia for coronary artery bypass surgery

  This study will test whether using the inhaled anesthetic desflurane instead of propofol during anesthesia reduces serious postoperative cardiac complications in adults having coronary artery bypass graft surgery.

  Recruiting at 3 sites Phase 3 Xijing Hospital · Fuzhou, Fujian and 13 other locations · NCT07116733

• Intrapleural ropivacaine after heart surgery

  This study will test whether putting ropivacaine into the pleural space through chest drains reduces pain and improves recovery for adults after heart surgery.

  Recruiting at 2 sites Phase 4 Saint Petersburg State University, Russia · Saint Petersburg and 1 other locations · NCT07116343

• Urine-sodium–guided fluid removal after heart surgery

  This trial will test whether using bedside urine sodium measurements to guide IV furosemide dosing helps adults who develop fluid overload after heart surgery get rid of excess fluid more safely and efficiently.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT07077772

• Exploring the tiny world inside the aortic valve during surgery

  This study tests the DNA and microbiota found in the blood and explanted aortic valve of patients undergoing valve replacement or repair.

  Recruiting University Hospital, Toulouse · Toulouse, France · NCT07075601

• Autologous Cold-Stored Platelets for Complex Cardiac Surgery

  This study tests whether using a patient’s own cold-stored platelets, donated 7–10 days before surgery, improves outcomes for adults undergoing complex cardiac procedures compared with standard allogeneic platelets.

  Recruiting Phase 2/3 University Health Network, Toronto · Toronto, Ontario · NCT07064954

• NeuroFirst brain protection for adults having heart bypass surgery

  This trial tests whether a bundled anesthesia approach called NeuroFirst can help people aged 60 and older having planned heart surgery with cardiopulmonary bypass avoid silent brain infarcts and thinking or memory problems after surgery.

  Recruiting at 5 sites Chinese Academy of Medical Sciences, Fuwai Hospital · Beijing, Beijing Municipality and 4 other locations · NCT07048002

• Urine Output Monitoring to Guide Fluid and Diuretic Therapy in Cardiac ICU Patients

  This observational study tests how continuous urine output data from the FIZE kUO device can help guide fluid therapy and diuretic use in adults after heart surgery.

  Recruiting FIZE Medical ltd · Petah Tikva · NCT07022314

• Can newly trained clinicians use bedside lung ultrasound to detect a collapsed lung after heart surgery?

  This study will test whether medical trainees can use a bedside lung ultrasound to find a collapsed lung in adults after heart surgery.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07018856

• Nicotinamide Mononucleotide for patients undergoing cardiac surgery

  This study tests whether taking NMN by mouth before and after heart surgery helps protect the heart and kidneys in adults at risk of complications.

  Recruiting Phase 2 Brigham and Women's Hospital · Boston, Massachusetts · NCT07013591

• How often difficult airways occur during heart surgery and creating a tool to predict them

  This project will try to measure how often adults having cardiovascular surgery experience difficult airways and build a prediction model to spot those at higher risk.

  Recruiting Diskapi Teaching and Research Hospital · Ankara · NCT06986187

• Sucrosomial oral iron versus standard iron care after heart surgery

  This trial will try sucrosomial oral iron to see if it raises hemoglobin as well as standard care in adults with iron deficiency or anemia after non-emergency heart surgery.

  Recruiting Early Phase 1 Englewood Hospital and Medical Center · Englewood, New Jersey · NCT06970925

• Using combined iron supplements to reduce blood transfusions in heart surgery patients

  This study is testing if a mix of iron supplements and vitamin C can help heart surgery patients with low iron levels need fewer blood transfusions.

  Recruiting Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang · NCT06968936

• Platelet ADP function and bleeding risk in adults having cardiac surgery with cardiopulmonary bypass

  We will test whether a preoperative thromboelastography ADP test can predict which adults having elective cardiac surgery with cardiopulmonary bypass will bleed or need blood transfusions.

  Recruiting Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León · Salamanca · NCT06961175

• How redox balance during heart surgery with bypass might predict short-term outcomes

  This observational study in adults having heart surgery with bypass tests whether redox balance markers can predict short-term post-operative outcomes.

  Recruiting University Hospital, Toulouse · Toulouse · NCT06840327

• Evaluating preoperative anxiety levels in cardiac surgery patients based on admission day

  This study is trying to see if the day patients are admitted for cardiac surgery affects their anxiety levels before the operation.

  Recruiting Rennes University Hospital · Rennes · NCT06794697

• Non‑drug, non‑invasive treatments given before heart surgery to protect the brain

  This trial will test whether remote ischemic preconditioning (RIPC) and transcranial electrical stimulation (tDCS) given before elective heart surgery can reduce stroke, delirium, and other brain complications in adults at high risk.

  Recruiting China National Center for Cardiovascular Diseases · Beijing, Beijing Municipality · NCT06791551

• Digital ERAS platform to shorten hospital stay after coronary artery bypass grafting

  This project tests a digital platform based on ERAS to see if it shortens hospital stays for adults having primary isolated CABG.

  Recruiting at 2 sites University of Sao Paulo General Hospital · São Paulo, São Paulo and 1 other locations · NCT06786819

• Evaluating protein levels in children undergoing cardiac surgery

  This study is testing how certain protein levels in children having heart surgery might relate to their recovery and complications after the operation.

  Recruiting Nantes University Hospital · Nantes · NCT06754709

• Using Remimazolam for Sedation in Patients After Heart Surgery

  This study tests if a new sedative called remimazolam can help heart surgery patients recover better and get off breathing machines faster compared to a standard sedative.

  Recruiting First Affiliated Hospital of Zhejiang University · Hangzhou, Zhejiang · NCT06716840

• Using Nitric Oxide to Improve Recovery in Heart Surgery

  This study tests if inhaling nitric oxide during heart surgery can help adults recover better and avoid complications like kidney problems and breathing issues.

  Recruiting Phase 3 Xijing Hospital · Boston, Massachusetts and 2 other locations · NCT06702553

• Assessing brain function during cardiac surgery

  This study is trying to find out what factors might lead to brain problems after heart surgery by checking patients' brain function before, during, and after the operation.

  Recruiting China National Center for Cardiovascular Diseases · Beijing · NCT06660602

• Angiotensin II to reduce kidney injury after heart surgery

  This trial tests whether angiotensin II, used as the primary blood-pressure medicine instead of norepinephrine after cardiac surgery with cardiopulmonary bypass, can lower the chance of moderate or severe acute kidney injury in adults at higher risk.

  Recruiting at 4 sites Phase 3 Universität Münster · Berlin and 3 other locations · NCT06615102

• Understanding chronic pain after heart surgery

  This study looks at what causes long-lasting pain in people aged 18-80 after heart surgery to help improve pain management for these patients.

  Recruiting Ankara Etlik City Hospital · Ankara, Ankara and 1 other locations · NCT06534372

• Comparing two types of cardioplegia in major heart surgery

  This study tests whether a type of heart surgery solution called Custodiol works just as well as another solution, Buckberg, in protecting the heart during major surgeries.

  Recruiting Phase 4 Hospital San Carlos, Madrid · Madrid, Madrid · NCT06530641

• Understanding cognitive recovery in older adults after heart surgery

  This study looks at how heart surgery affects the thinking and memory skills of older adults aged 65 and up, and it also gathers insights from their family members about these changes.

  Recruiting Karolinska Institutet · Gothenburg · NCT06469515

• Using non-steroidal anti-inflammatory drugs for pain management after heart surgery

  This study tests if using non-steroidal anti-inflammatory drugs can safely help manage pain after heart surgery without causing complications.

  Recruiting Phase 3 Centre Hospitalier Universitaire, Amiens · Amiens · NCT06381063

• Using intravenous iron to treat anemia after heart surgery

  This study is testing if giving intravenous iron to patients with anemia after heart surgery can help them stay out of the hospital and feel better.

  Recruiting at 3 sites Phase 2 University Health Network, Toronto · Kingston, Ontario and 2 other locations · NCT06287619

• Guided fluid removal using VeXUS score for patients with acute kidney injury after heart surgery

  This study is testing if using the VeXUS score to manage fluid levels can help patients with acute kidney injury after heart surgery recover better than standard care.

  Recruiting Hospices Civils de Lyon · Bron, Bron and 1 other locations · NCT06251713

• Combined iron supplementation to reduce blood transfusions in cardiac surgery

  This study tests if a new combination of iron, a hormone, and vitamin C can help adults with iron-deficiency anemia needing heart surgery avoid blood transfusions.

  Recruiting Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang · NCT06012760

• Evaluating a noninvasive method to measure blood flow in cardiac surgery patients

  This study is testing a new, noninvasive way to measure blood flow during heart surgery to see if it works as well as the traditional method for patients on ventilators.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT05944146

• Using LSALT peptide to prevent kidney injury in heart surgery patients

  This study is testing if a new peptide can help prevent kidney injury in patients having heart surgery.

  Recruiting at 4 sites Phase 2 Arch Biopartners Inc. · Calgary, Alberta and 8 other locations · NCT05879432

• Investigating the role of angiopoietins in cardiac surgery outcomes

  This study is trying to see if measuring certain proteins in the blood can help predict complications for adults having heart surgery.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT05817929

• Using a smartwatch to diagnose postoperative atrial fibrillation

  This study is testing whether a smartwatch can help doctors find out if patients who just had heart surgery develop a common heart rhythm problem called atrial fibrillation while they are still in the hospital.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT05573633

• Innovative treatment for perioperative anaemia in cardiac surgery patients

  This study is testing a new combination treatment of iron, a hormone, and vitamin C to see if it can help people with low iron levels feel better before heart surgery.

  Recruiting Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang · NCT05353348

• Understanding Atrial Fibrillation in Cardiac Surgery Patients

  This study looks at how common atrial fibrillation is in patients having heart surgery by using a wearable heart monitor to see how it affects their recovery and hospital stays.

  Recruiting Brigham and Women's Hospital · Boston, Massachusetts · NCT04880265

• Comparing blood transfusion strategies in younger patients undergoing heart surgery

  This study tests which blood transfusion method works better for younger patients having heart surgery to help them recover more smoothly and avoid complications.

  Recruiting at 47 sites Unity Health Toronto · Portland, Maine and 53 other locations · NCT04754022

• Predicting Delirium Risk After Heart Surgery Using a New Cognitive Tool

  This study is testing a new app to see if it can help doctors predict which older patients are at risk of developing confusion after heart surgery.

  Recruiting University Hospital, Basel, Switzerland · Basel · NCT03360838

NIH-funded research (38)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• AI-powered system to improve teamwork in cardiac surgery

  A research project is testing an AI-driven system that listens to team conversations during heart surgeries to spot teamwork patterns and give real-time feedback to improve patient safety.

  NIH research University of Colorado · Boulder, UNITED STATES · NIH-11579799

• AKI-related delirium after heart surgery

  This grant funds research to understand why some people develop delirium after heart surgery when they also have acute kidney injury.

  NIH research University of Iowa · Iowa City, United States · NIH-11477480

• Predictors of widespread pain after cardiac surgery

  A clinician-scientist at UNC Chapel Hill is studying why some patients develop widespread, nociplastic-like pain after heart surgery and ICU stay, to improve prevention and care.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11452390

• Statistical methods to link high-dimensional heart-surgery data with outcomes

  This grant tests advanced data methods to find links between detailed intraoperative heart-surgery measurements and patient outcomes after procedures like CABG.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11448221

• Wearable ultrasound patch to monitor heart health after pediatric heart surgery

  A small, disposable ultrasound patch worn on babies and young children after heart surgery will measure heart function and blood pressure in real time, aiming to catch problems early.

  NIH research George Mason University · Fairfax, United States · NIH-11438465

• Using smart computer predictions to prevent kidney injury after heart surgery

  A machine-learning approach uses routinely collected hospital data to predict who might develop acute kidney injury after heart surgery, so clinicians can act early.

  NIH research Baylor College of Medicine · Houston, United States · NIH-11417314

• Norepinephrine vs phenylephrine to reduce kidney injury after major non-cardiac surgery

  A large, real-world trial will compare two common vasopressors to see which helps prevent kidney injury after major non-heart surgeries.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11400034

• Soluble guanylyl cyclase stimulation to protect organs after heart surgery

  A doctor-led study in adults undergoing cardiac surgery tests whether boosting a key blood-vessel signal helps prevent kidney and brain injuries.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11393334

• Fluvoxamine to prevent delirium after non‑cardiac surgery

  Seeing if taking the antidepressant fluvoxamine around non‑cardiac surgery can lower inflammation and reduce the chance or severity of postoperative delirium in adults, including those with Alzheimer‑type dementia.

  NIH research Washington University · Saint Louis, United States · NIH-11383660

• Intelligent Perfusion Digital Twin to Improve Cardiac Surgery Safety

  A new AI-powered digital twin will help perfusionists managing heart-lung bypass during cardiac surgery to keep patients safer and reduce avoidable complications.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11382365

• Personalized prevention of AKI after heart surgery using new machine learning methods

  A clinician-scientist fluent in nephrology and critical care is using advanced data mining and machine learning to tailor prevention strategies for kidney injury in patients undergoing cardiac surgery.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11370634

• Cardiac Surgery Anesthesia Best Practices to Reduce Kidney Injury

  A research project at a major university aims to reduce kidney injury after heart surgery by improving anesthesia and intraoperative care.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11353817

• Preoperative risk predictor for cardiac surgery using a smartphone dynamometer

  A smartphone app that turns your phone into a hand-grip test to help predict surgical risks before elective heart surgery.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11335676

• Tailoring blood pressure to protect brain blood flow during and after heart surgery

  Aims to see if monitoring each person's brain blood-flow limits and personalizing blood-pressure targets during and after heart surgery reduces delirium and longer-term memory and thinking problems.

  NIH research Stanford University · Stanford, United States · NIH-11310140

• Preventing early hardening and breakdown of heart implants in children

  This project looks at why patches, conduits, and bioprosthetic valves used in children's heart surgery harden and fail sooner than in adults and tests ways to make them last longer for pediatric patients.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11292864

• Comparing how heart inotropes are used after surgery

  Researchers will look at how doctors decide to use heart-strengthening medicines after heart surgery and why some patients fare better or worse.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11229615

• Using smartphone technology to predict risks of complications after heart surgery

  This study is testing a new smartphone app that helps you check your hand grip strength at home, so doctors can better understand your fitness level before elective heart surgery and help you recover more safely.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11192921

• Fluvoxamine to reduce delirium after non-cardiac surgery

  This project gives fluvoxamine around non-cardiac surgery to adults with Alzheimer-type or related dementias to try to lower the chance or severity of postoperative delirium.

  NIH research Washington University · Saint Louis, United States · NIH-11189815

• Creating 3D models to improve heart surgery for children with severe congenital heart disease

  This study is all about helping kids with serious heart problems by using special 3D models of their hearts, so doctors can plan the best surgery for each child and make sure they have the best chance of a successful recovery.

  NIH research West Virginia University · Morgantown, United States · NIH-11180747

• Which blood‑pressure drug during major surgery better protects the kidneys

  This compares two common medicines given for low blood pressure during major non‑cardiac surgery to find which one best prevents sudden kidney injury in adults.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11176032

• Understanding Kidney Problems After Heart Surgery

  This research looks at specific blood markers to understand why some people develop kidney problems after heart surgery, hoping to find ways to prevent it.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11163318

• Improving anesthesia practices to prevent kidney injury after heart surgery

  This study is looking at how better anesthesia techniques during heart surgery can help protect your kidneys and reduce the chances of kidney problems afterward, so if you're having heart surgery, this research is all about making your recovery safer and healthier.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11163225

• Stimulating blood-vessel signaling to protect kidneys and brain during heart surgery

  People having heart surgery will receive a medicine that boosts blood-vessel signaling to try to reduce kidney injury and delirium.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11141591

• Cyclohexanone exposure during infant heart surgery and child development

  This project looks at whether a chemical that can leach from plastic medical devices used in infant heart operations is linked to heart recovery and later brain development in babies and young children.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11083069

• Understanding why heart implants fail faster in children and finding ways to improve them

  This study is looking into why heart implants for kids wear out quickly, so researchers can find ways to make them last longer and help reduce the number of surgeries children need.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11009963

• Examining how heart medications are used in cardiac surgery

  This study is looking at how heart medications called inotropes are used to help patients recover after heart surgery, so we can find the best ways to use them safely and effectively for everyone.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-10999426

• Understanding the genetics behind heart rhythm problems after heart surgery

  This study is looking at how our genes might play a role in causing heart rhythm problems after surgery for people having heart operations, and it's for patients who want to understand their risk of developing these issues.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-10985437

• Investigating how a specific enzyme affects blood vessel function and organ injury during heart surgery

  This study is looking at how a specific enzyme affects blood vessel function and can lead to problems like kidney and brain injuries during heart surgery, with the goal of finding ways to help patients recover better and stay healthier after their procedures.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-10917127

• Improving heart health after cardiac surgery using a vitamin-like compound

  This study is looking at whether taking nicotinamide can help protect your heart and kidneys after heart surgery, and it will involve 304 patients who will either get the nicotinamide or a placebo to see how well it works and if it's safe.

  NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-10903960

• Using machine learning to prevent kidney injury after heart surgery

  This study is looking to improve care for patients who might develop kidney problems after heart surgery by using smart computer techniques to create personalized plans that help manage their fluids and blood pressure better.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-10894799

• Understanding brain blood flow and its effects on recovery after heart surgery

  This study is looking at how blood flow to the brain after heart surgery can affect your thinking and memory, and it aims to find the best ways to manage your blood pressure during recovery to help prevent problems like confusion and memory loss.

  NIH research Stanford University · Stanford, United States · NIH-10883892

• Investigating blood pressure levels after heart surgery and their link to kidney injury

  This study is looking at how blood pressure in the first day after heart surgery might affect the chances of developing kidney problems, and it's for patients who have just had heart surgery to help find the best blood pressure levels to keep them safe.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-10877008

• Investigating infections after heart surgery

  This study is looking into why some people get infections after heart surgery and aims to find ways to prevent these infections, helping patients have a safer recovery.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-10864996

• Comparing two medications to prevent kidney injury after surgery

  This study is looking at how well two medications, norepinephrine and phenylephrine, can help prevent kidney problems after major surgery for patients who are at risk of low blood pressure during their operation.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-10860868

• Factors affecting participation in cardiac rehabilitation after heart surgery

  This study is looking into why some people don’t join cardiac rehabilitation after heart surgery, even though it can really help them recover and feel better, and it aims to find ways to encourage more patients to take part in these important programs.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-10851738

• Reducing the need for reintubation in high-risk cardiac surgery patients using high-flow nasal cannula.

  This study is looking at how well high-flow nasal cannula therapy can help prevent the need for reintubation in patients who have just had heart surgery, especially those with other health problems, to improve their recovery and care after the operation.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-10819218

• Improving the quality of cardiac surgery through better assessments

  This study is looking at ways to make heart surgery safer and more effective by checking how well surgical teams work together and their skills during the operation, especially for patients getting bypass surgery.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-10745715

• A device to measure heart volumes after cardiac surgery

  This study is working on a new device that helps doctors measure heart volumes in older patients recovering from heart surgery, so they can better manage their care and improve recovery outcomes.

  NIH research Bridgesource Medical Corporation · Austin, United States · NIH-10707900

Related topics

Quick answers

How many Cardiac Surgery clinical trials are recruiting right now?

59, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 26 countries. The most sites are in China (13 trials), France (10 trials), Turkey (Türkiye) (7 trials), United States (6 trials), Canada (5 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 4, Phase 2: 3, Phase 4: 3, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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