Clinical trial Recruiting at 1 site Interventional Ages 75 and up

Frailty score predicts quality of life after emergency heart surgery in people 75 and older

Official title: SAGE-Heart : Senior Assessment fraGility and Post-opErative QALYs 1 Year After Emergency HEART Surgery for Patients Aged 75 and Older

Run by University Hospital, Bordeaux · NCT07677319 · Data updated 2026-11-12

This study tests whether a preoperative frailty score can predict quality of life one year after emergency heart surgery in patients aged 75 and up.

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Quick facts

Study typeInterventional
Ages75 Years and up
SexAll
Enrollment265 (estimated)
SponsorUniversity Hospital, Bordeaux
Academic / other
Locations1 site (Bordeaux, France)
StatusRecruiting
StartedDecember 3, 2025
Main results expectedDecember 3, 2028
Study endsDecember 3, 2028
Registry record updatedJune 30, 2026
Trial IDNCT07677319 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients aged 75 years or older undergoing emergency cardiac surgery with cardiopulmonary bypass who can provide informed consent and have a measurable Clinical Frailty Scale score preoperatively.

Probably not a fit

Patients who are not frail or who experience non-modifiable postoperative complications may see limited or no benefit in terms of predicted quality-adjusted life years.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study examines if the Clinical Frailty Scale measured before surgery can forecast the loss or preservation of quality-adjusted life years one year after emergency cardiac surgery with cardiopulmonary bypass in adults aged 75 and older. Data are collected during the anesthesia consult, including the CFS and a standardized quality-of-life measure (EuroQoL 5D-5L). The trial focuses on elderly patients undergoing immediate or urgent CPB surgery, aiming to inform decisions and care planning in high-risk cases. The initiative acknowledges the growing use of CPB in the oldest populations and seeks to improve understanding of long-term outcomes beyond short-term mortality. Phone-based follow-ups are used to collect outcomes related to quality of life and survival.

Why it matters

Potential benefit: If successful, the study could help clinicians better predict long-term quality of life for frail elderly patients after emergency heart surgery and tailor discussions and care plans accordingly.

How similar studies have gone: Previous research suggests frailty assessments can inform risk in elderly surgical patients, but long-term QALY predictions in emergency CPB contexts remain an area of ongoing study.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged ≥ 75 years who are affiliated with or beneficiaries of a social security scheme and undergoing emergency cardiac surgery under cardiopulmonary bypass, either immediate or urgent (relative) :

  * Immediate emergency surgery: intervention performed before the start of the next working day following the decision to operate,
  * Urgent (relative) emergency surgery: patients not admitted electively for surgery but requiring an intervention during the current hospital stay for medical reasons, and who cannot be discharged without undergoing a definitive procedure

Exclusion Criteria:

* Patients requiring preoperative cardiopulmonary resuscitation
* Scheduled (elective) surgery
* Lack of informed consent
* Impaired consciousness at the time of inclusion (defined by a Glasgow Coma Scale score \< 15)
* Individuals under legal guardianship or judicial protection
* Individuals participating in another interventional research protocol

Where it's running

  • University Hospital, Bordeaux
    Bordeaux, France, France
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.