Understanding cognitive recovery in older adults after heart surgery
Official title: Enhanced Continuity of Postoperative Care for Older People in Their Neurocognitive Recovery After Cardiac Surgery
Run by Karolinska Institutet · NCT06469515 · Data updated 2026-11-12
This study looks at how heart surgery affects the thinking and memory skills of older adults aged 65 and up, and it also gathers insights from their family members about these changes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 65 Years and up |
| Sex | All |
| Enrollment | 220 (estimated) |
| Sponsor | Karolinska Institutet Academic / other |
| Locations | 1 site (Gothenburg) |
| Status | Recruiting |
| Started | November 1, 2024 |
| Main results expected | June 2027 |
| Study ends | June 2027 |
| Registry record updated | November 9, 2026 |
| Trial ID | NCT06469515 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals aged 65 and older who are scheduled for elective or urgent cardiac surgery.
✕Probably not a fit
Patients with physical, mental, or cognitive difficulties that prevent them from completing cognitive tests will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the neurocognitive function of older adults aged 65 and above following cardiac surgery. It will evaluate the incidence of postoperative cognitive decline and identify risk factors affecting cognitive performance over a period of up to six months post-surgery. The study will also explore the experiences of close relatives regarding the cognitive changes observed in patients. A total of 220 participants will be included, and various cognitive domains such as memory, attention, and executive functions will be measured.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of cognitive decline in older patients after cardiac surgery.
How similar studies have gone: Other studies have shown varying degrees of success in understanding postoperative cognitive dysfunction in older adults, making this approach both relevant and necessary.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Scheduled for elective or urgent open-heart surgery or minimally invasive cardiac surgery * Resident in the area/region for the current thoracic clinic * Able to read and understand Swedish Exclusion Criteria: * Physical, mental, and cognitive difficulties that prevent the individual from completing the cognitive tests * Undergone surgery within the last 6 months
Where it's running
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Sahlgrenska University Hospital
Gothenburg, Sweden Recruiting
Study contacts
- Study coordinator: Lina Bergman, PhD
- Email: lina.bergman@ki.se
- Phone: 0046 8 524 836 66
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Predicting Delirium Risk After Heart Surgery Using a New Cognitive Tool
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Total Intravenous Versus Inhalational Anesthesia in Hip Fracture Surgery
This study compares TIVA with sevoflurane anesthesia in people 65 and older undergoing hip fracture surgery to see which method helps them recover better after surgery.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.