NIH-funded research R21 grant

Wearable ultrasound patch to monitor heart health after pediatric heart surgery

Official title: Wearable ultrasound patch for noninvasive hemodynamic monitoring after pediatric cardiac surgery

Funded at George Mason University · NIH-11438465 · Data updated 2026-11-12

A small, disposable ultrasound patch worn on babies and young children after heart surgery will measure heart function and blood pressure in real time, aiming to catch problems early.

More Ultrasound research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionGeorge Mason University
NIH-funded
Lab location1 site (Fairfax, United States)
Project startAugust 15, 2026
Project endJuly 31, 2028
Funding year2026
Award (this year)$265,018
NIH project number1R21EB040377-01
Project IDNIH-11438465 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are neonates and infants (0–1 year) who have undergone cardiac surgery and require close post-operative hemodynamic monitoring.

Less likely to help

The device may not benefit patients who do not have immediate post-operative monitoring needs or who are not surgical candidates.

What this research studies

This project develops a lightweight, wearable ultrasound patch made with 3D printing to monitor cardiac output and blood pressure continuously in neonates and infants (0–1 year). Researchers will test the device in lab settings and in vivo using a juvenile pig model to show it can provide accurate, angle-insensitive measurements. The goal is to enable real-time bedside monitoring so clinicians can intervene sooner and improve outcomes after pediatric cardiac surgery. The approach combines a miniaturized patch, a tunable steering array, and advanced signal processing to extract meaningful hemodynamic signals from ultrasound. If successful, this could change how post-operative care is managed for the smallest patients and reduce complications related to LCOS and graft issues.

Why it matters

Potential benefit: If successful, patients could receive earlier intervention for hemodynamic instability after surgery, potentially reducing complications and improving survival.

How similar studies have gone: Previous work shows promise for noninvasive monitoring with ultrasound, but this specific disposable wearable patch for real-time pediatric post-surgical monitoring is novel.

Where this research is happening

  • George Mason University
    Fairfax, United States
    Active

Researchers

  • Principal investigator: Sikdar, Siddhartha — George Mason University
  • Study coordinator: Sikdar, Siddhartha

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.