Condition
Anemia clinical trials and research
As of November 12, 2026, Find a Trial lists 58 Anemia clinical trials that are recruiting, at sites in 45 countries (most in United States (16), China (11), Germany (7)). By phase: Phase 2 (9), Phase 3 (4), Phase 4 (4), Phase 1/2 (3). The most active sponsors are Disc Medicine, Inc (4), Hospital Universitari Vall d'Hebron Research Institute (2), Second Affiliated Hospital, Zhejiang University, School of Medicine (2). There are also 97 NIH-funded research projects on Anemia, with $41.9 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 58Clinical trials
- 97NIH research projects
- 45Countries
Newest Anemia clinical trials
All recruiting trials (58)
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Iron status at ICU discharge in adults with anemia after critical illness
We are testing whether iron deficiency is common at ICU discharge and whether it relates to how well patients recover after leaving the ICU.
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Luspatercept for anemia due to chronic kidney disease
This study tests whether luspatercept can raise hemoglobin levels in people with anemia caused by CKD and whether it is safe.
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Delayed vs Immediate Umbilical Cord Clamping in Preterm Birth
This trial tests whether delaying the clamping of the umbilical cord after birth helps preterm babies more than clamping right away.
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Elritercept vs. placebo for adults with myelofibrosis and anemia on ruxolitinib
This study tests whether elritercept can improve anemia in adults with myelofibrosis who are taking ruxolitinib, compared with placebo.
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CTX001: a pill to help iron move where it’s needed in healthy adults
This early test checks if CTX001 is safe and how it behaves in the body to help iron get into red blood cells in healthy adults, with or without iron and with or without food.
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Sucrosomial iron for children with celiac disease and iron deficiency
This trial tests whether adding oral Sucrosomial® (Sideral forte®) iron drops to a gluten-free diet helps children aged 8–18 with newly diagnosed celiac disease and low iron or anemia recover hemoglobin and iron stores faster than diet alone.
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Genetic causes of congenital sideroblastic anemia
This project will test whether detailed genomic analysis of blood samples can identify genetic causes of congenital sideroblastic anemia in people not explained by routine gene panels.
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Elritercept versus epoetin alfa for transfusion-dependent anemia in lower-risk MDS
This study tests whether elritercept can reduce the need for red blood cell transfusions and improve fatigue compared with epoetin alfa in adults with very low-, low-, or intermediate-risk myelodysplastic syndromes who need regular transfusions.
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Bringing multiple micronutrient supplements to pregnant women in Takeo Province, Cambodia
This project will see if giving pregnant women in Takeo Province MMS (multiple micronutrient supplements) can be delivered effectively through local health centers.
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Ferric citrate for iron deficiency anemia in pregnancy
This trial compares ferric citrate to ferrous fumarate to see if the iron pill works better and is easier to tolerate for pregnant people in the second trimester with moderate to severe iron deficiency anemia.
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DISC-0974-201 for adults with IBD-related anemia
This Phase 2 trial will test whether DISC-0974-201 helps adults with inflammatory bowel disease who have anemia driven by inflammation.
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DISC-0974-201 for adults with IBD-related anemia
This Phase 2 trial will test whether DISC-0974-201 helps adults with inflammatory bowel disease who have anemia driven by inflammation.
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Quality-of-life–guided red blood cell transfusions for people with refractory MDS or AML
We test whether using routine EQ-5D-5L quality-of-life scores to decide when to give red blood cell transfusions can safely reduce the number of transfusions for adults with refractory MDS or AML who are receiving only palliative care.
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Improving ready-to-use therapeutic foods to help malnourished Kenyan children absorb iron
This project will test whether changing the iron in ready-to-use therapeutic foods helps severely malnourished Kenyan children absorb iron better and recover from anemia.
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Sucrosomial Iron versus Ferric Maltol for iron-deficiency anemia in women
This trial will test whether Sucrosomial Iron works as well as Ferric Maltol to raise hemoglobin in adult women with mild to moderate iron deficiency anemia over 12 weeks.
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Nelfinavir to improve anemia in people with myelofibrosis by restoring iron delivery to the bone marrow
This trial tests whether the antiviral drug nelfinavir can help people with myelofibrosis and anemia by raising hemoglobin and lowering blood markers of fibrosis.
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Preoperative IV ferric derisomaltose to prevent anemia and improve quality of life in obese patients having bariatric surgery
This trial tests whether a single preoperative IV ferric derisomaltose dose, compared with saline placebo, prevents postoperative anemia and improves quality of life for iron-deficient obese patients undergoing bariatric surgery.
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Integrated diagnosis for sickle cell disease and other rare anemias
This project tests whether combining genetic testing, LoRRca ektacytometry, and microfluidic analysis can improve diagnosis and predict disease course for people with sickle cell disease and other inherited anemias.
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National registry for people with myelofibrosis and anemia in Germany.
This project will collect health, treatment, and quality-of-life information from people in Germany with primary or secondary myelofibrosis and anemia to see how their care and symptoms change over time.
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National registry for people with myelofibrosis and anemia in Germany.
This project will collect health, treatment, and quality-of-life information from people in Germany with primary or secondary myelofibrosis and anemia to see how their care and symptoms change over time.
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Using combined iron supplements to reduce blood transfusions in heart surgery patients
This study is testing if a mix of iron supplements and vitamin C can help heart surgery patients with low iron levels need fewer blood transfusions.
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Intravenous iron to help people regain mobility after hip fracture surgery
This trial will test whether a single infusion of intravenous iron given soon after hip fracture surgery helps people aged 65 and older regain their walking ability.
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Improving blood management practices in Central Eastern Europe hospitals
This study is testing how well hospitals in Central Eastern Europe can improve their blood management practices to better care for patients and reduce unnecessary blood transfusions after they receive training.
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Using luspatercept to improve low blood cell counts in patients with clonal cytopenias of uncertain significance
This study is testing if a drug called luspatercept can help people with low blood cell counts due to clonal cytopenias of uncertain significance feel better and improve their blood levels over 24 weeks.
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Treatment of chemotherapy-induced anemia with SAL-0951
This study is testing a new treatment called SAL-0951 to see if it can help people with cancer who are experiencing anemia from chemotherapy feel better.
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Using Epoetin Alfa and Iron Derisomaltose to Treat Anemia in Sepsis Patients
This study is testing if a combination of epoetin alfa and iron derisomaltose can help improve anemia in patients with sepsis in the ICU, instead of using blood transfusions.
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Improving blood management for patients undergoing heart surgery
This study is testing if giving patients iron before heart surgery can help them recover better and need fewer blood transfusions.
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Caregiver training for screening malnutrition relapse in children
This study is testing if training caregivers to measure their children's arm size can help catch malnutrition relapses in kids who have recently recovered from severe malnutrition.
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Comparing blood transfusion thresholds in patients on ECMO
This study tests whether giving fewer blood transfusions is safe and effective for adults on ECMO compared to giving more transfusions.
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Choline for infants with iron deficiency anemia
This trial will see if giving choline together with iron to 6-month-old infants with iron deficiency anemia improves their brain development.
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Examining the impact of preoperative anemia on surgical complications
This study is trying to see how different types of anemia before surgery affect the risk of complications during and after moderate- to high-risk surgeries.
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Platform for Rare Blood Disorders in Europe
This study is trying to gather and share information about rare blood disorders across Europe to help researchers understand these conditions better and improve treatment options for patients.
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Using stem cell exosomes to help recover from chemotherapy side effects in leukemia patients
This study is testing if giving leukemia patients special stem cell treatments can help them recover better from the side effects of chemotherapy.
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Peking University Weifang Birth Cohort
This project will follow pregnant women in Weifang and their children to see if pre-pregnancy and prenatal exposures affect maternal and child health up to age 18.
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Anemia after bariatric surgery
We will follow people aged 16–70 having sleeve gastrectomy or Roux-en-Y gastric bypass to see how often anemia develops soon after surgery and over the long term and what factors predict it.
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Early angioplasty for diabetic foot syndrome
This study is testing if getting a quick angioplasty after being diagnosed with diabetic foot ulcers helps heal the wounds better than waiting for the procedure.
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Echocardiographic changes in elderly patients after blood transfusion
This study is testing how blood transfusions affect heart function in elderly patients by checking their heart images before and after the transfusion.
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Iron supplementation for adolescents with scoliosis
This study tests if giving iron supplements to teenagers with scoliosis before their surgery can help them recover better and need fewer blood transfusions.
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Using 129Xe MRI to study lung and blood conditions
This study is testing how a special MRI using 129Xe gas can help us understand lung and blood conditions better by looking at healthy people and those with specific lung diseases.
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Combined iron supplementation to reduce blood transfusions in cardiac surgery
This study tests if a new combination of iron, a hormone, and vitamin C can help adults with iron-deficiency anemia needing heart surgery avoid blood transfusions.
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Investigating the effects of iron deficiency anemia on brain function
This study is testing how iron deficiency anemia affects brain function in adult women and whether treating it with iron can improve their cognitive abilities.
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Treatment of anemia in patients with myelodysplastic syndromes using Luspatercept
This study is testing if Luspatercept can help people with myelodysplastic syndromes and anemia, who haven't responded to other treatments, feel better and reduce their need for blood transfusions.
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Understanding chronic kidney disease in Sub-Saharan Africa
This study is trying to understand how common chronic kidney disease is in Sub-Saharan Africa and what factors might be causing it by looking at the health and lifestyle of adults in the Bagamoyo district.
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Using iron infusions to treat anemia in cancer patients before surgery
This study tests if giving iron infusions to cancer patients before surgery can help improve their blood levels and reduce the need for blood transfusions during chemotherapy.
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Investigating APG-5918 for Anemia Treatment
This study is testing a new drug called APG-5918 to see if it can safely and effectively treat anemia in patients who have it, while also checking how it works in healthy people.
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Combined evidence-based steps to make primary care diagnosis safer and faster
This project will test whether combining three evidence-based steps for primary care teams makes diagnosing anemia and reduced kidney function safer and faster for patients at participating clinics.
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Comparing individualized and conventional blood transfusion strategies during ECMO for heart failure
This study is testing whether a personalized blood transfusion approach during heart support treatment can help patients use less blood and have better outcomes compared to the standard method.
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Improving management of anemia before surgery
This study looks at how well doctors are following new guidelines to manage anemia in patients with chronic kidney disease before their surgeries to see if it helps them have better outcomes.
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Using ferric derisomaltose to improve recovery in gynecologic cancer surgery
This study is testing if an iron treatment can help women with gynecologic cancer surgery recover better by improving their iron levels and reducing the need for blood transfusions.
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Luspatercept for treating anemia in low-risk myelodysplastic syndromes
This study is testing if Luspatercept can help people with low-risk myelodysplastic syndromes who have anemia feel better without needing blood transfusions.
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Investigating the link between FGF23 and cardiovascular damage in anemia and chronic kidney disease.
This study is trying to see if high levels of a protein called FGF23 are linked to heart problems in people with anemia, whether or not they also have chronic kidney disease.
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Evaluating DISC-0974 for treating anemia in myelofibrosis patients
This study tests if a new treatment called DISC-0974 can help people with myelofibrosis who have anemia feel better and improve their condition.
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Evaluating DISC-0974 for treating anemia in myelofibrosis patients
This study tests if a new treatment called DISC-0974 can help people with myelofibrosis who have anemia feel better and improve their condition.
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Integrated diagnosis and treatment for chronic kidney disease outcomes
This study is trying to see if a combined approach to diagnosing and treating chronic kidney disease can help patients manage their health better and improve their overall outcomes.
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Managing preoperative anemia and blood transfusion in elective surgeries
This study is testing whether better management of anemia before elective surgeries can help patients avoid complications and improve their treatment outcomes.
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Assessing the impact of comorbidities on postoperative complications.
This study looks at how having other health issues affects the chances of complications after abdominal surgery to help doctors better understand and manage risks for their patients.
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A large cohort study on prenatal and early life factors affecting children's health in China
This study looks at how things like pregnancy and early feeding habits affect the health and growth of children in China.
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Registry for patients with Diamond Blackfan anemia
This study is creating a registry to collect information from people with Diamond Blackfan anemia to better understand the condition and its complications.
NIH-funded research (newest 40 of 97)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Hydroxyurea to help children with sickle cell anemia in Africa
A pediatric study tests hydroxyurea treatment for young children with sickle cell anemia in several African countries to see if it can reduce illness and improve health.
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Hydroxyurea for Children with Sickle Cell in Africa
A pilot study tests hydroxyurea in young children with sickle cell disease across several African countries to see if it can reduce illness and hospital visits.
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Hydroxyurea for Children with Sickle Cell Disease in Africa
A safe and feasible use of hydroxyurea for young children with sickle cell disease in several African countries to reduce illness and improve daily life.
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Stem cell problems in Diamond-Blackfan anemia
This project looks at why blood-forming stem cells don't work well in Diamond-Blackfan anemia by studying the common RPS19 gene change and its effects on TP53 and PRC2 pathways.
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Mobile phone-based screening for anemia in young children in western Kenya
A low-cost, phone-based screening approach helps identify anemia in young children in western Kenya so they can get timely care.
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Reducing anemia for newly married women in Nepal with home norms and micronutrients
A program to help newly married women in Nepal improve iron status and overall health through household behavior changes and micronutrient supplements.
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Emapalumab for children with aplastic anemia
Doctors will give emapalumab to children with acquired aplastic anemia to try to stop the immune attack on the bone marrow and help it make blood cells.
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Clinical and immunologic study of pediatric severe aplastic anemia to personalize care
A pediatric-focused research effort will collect and study immune and clinical data to tailor treatments for children with severe aplastic anemia.
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Aplastic Anemia Registry to Understand How Immune and Genetic Discoveries Affect Disease
A collaborative registry study to learn how genetic background and immune factors influence aplastic anemia and related bone marrow failure conditions in patients.
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In vivo gene repair to restore healthy hematopoiesis in Fanconi anemia
A study aims to repair faulty genes inside patients’ blood-forming cells to help people with Fanconi anemia regain healthy blood cell production.
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Understanding genetic dependencies when Fanconi anemia pathway is lost
A study to find other genes or pathways that cancer cells rely on when the Fanconi anemia repair system is broken, with the aim of guiding future treatments.
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Hypoxemia during Sleep in Sickle Cell Disease: How Common is It and How Might Treatments Help
This study looks at how low oxygen during sleep affects adults with sickle cell disease and how they respond to therapy across multiple urban and rural sites.
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Innovative cell and gene therapy approaches to treat Fanconi anemia
A Stanford-led project aims to develop safer cell and gene therapies to help people with Fanconi anemia who have bone marrow failure.
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Hypoxic red blood cells for sickle cell anemia using the Hemanext ONE system
A new approach using special low-oxygen red blood cells from the Hemanext ONE system is being tested to help adults and children with sickle cell anemia who rely on frequent transfusions.
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Hydroxyurea for Children with Sickle Cell Anemia in Africa
A safety and feasibility pilot study tests giving hydroxyurea to young children with sickle cell anemia in sub-Saharan Africa to reduce illness and death.
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Mobile phone screening for anemia in young children in western Kenya
A low-cost, phone-based screening approach is tested to identify anemia in young children in western Kenya so they can get timely treatment.
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Mobile phone screening for anemia in young children in western Kenya
This project uses a mobile-phone tool to find anemia in young children in western Kenya so they can get follow-up testing and care.
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Hydroxyurea for children with sickle cell anemia in sub‑Saharan Africa
This project gives hydroxyurea to young children with sickle cell anemia in sub‑Saharan Africa to find safe dosing and reduce sickle‑related complications.
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Hydroxyurea for young children with sickle cell anemia in sub‑Saharan Africa
This project gives hydroxyurea to young children with sickle cell anemia in sub‑Saharan Africa to reduce painful crises, hospital stays, and early death.
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Hydroxyurea for young children with sickle cell anemia in sub-Saharan Africa
Hydroxyurea is given to young children with sickle cell anemia in sub-Saharan Africa to improve health and reduce sickle-related complications.
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Hydroxyurea treatment for young children with sickle cell anemia in Africa
Giving hydroxyurea to young children with sickle cell anemia in several African countries to reduce sickle-related problems while monitoring safety.
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Reducing anemia before birth with a patient-centered toolkit
A new Stanford-led project aims to prevent iron deficiency anemia in pregnant people by using a toolkit and community partnerships to keep hemoglobin higher at birth.
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Iron‑deficiency anemia and its impact on brain function in late childhood
This study looks at how iron-deficiency anemia in late childhood and adolescence may affect thinking skills and brain development in young females.
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Environmental enteric dysfunction and anemia in young children with gut infections
A study in young children with gut parasites will look at how gut problems may affect drug absorption and cause anemia.
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Brain blood flow and oxygen use in adult iron deficiency anemia
This study looks at how moderate iron deficiency anemia in adults affects brain blood flow, oxygen use, and thinking abilities, and whether iron treatment can reverse any problems.
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Mobile phone screening for anemia in young children in western Kenya
Uses a mobile phone approach to find anemia in young children in western Kenya.
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Machine learning to predict iron deficiency risk in babies based on mom’s stress during pregnancy
A fast, data-driven approach uses a mother’s stress during pregnancy to help predict which babies might be at risk for iron deficiency anemia.
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Hydroxyurea treatment for children with sickle cell anemia in sub-Saharan Africa
Hydroxyurea given to young children with sickle cell anemia in sub-Saharan Africa to reduce pain, infections, and early death.
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How anemia and blood transfusions affect the newborn liver and gut
This project looks at how anemia and red blood cell transfusions affect the liver and gut in very premature newborns to help prevent transfusion-related intestinal injury.
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A fast, at-a-glance genetic test for recently transfused sickle cell patients in low-resource settings
A new quick, inexpensive genetic test could give accurate sickle cell results right after a blood transfusion, even in low-resource clinics.
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Reducing anemia in young Nepali women with household behavior change and micronutrients
A program in Nepal tests combining group-based education for newly married women, husbands, and mothers-in-law with micronutrient supplementation to reduce anemia and improve maternal and child health.
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Lowering anemia in newly married women in Nepal with family group sessions and supplements
This project uses household group education with husbands and mothers-in-law plus daily micronutrient supplements to help newly married Nepali women improve nutrition and reduce anemia before pregnancy.
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Eltombopag: a new way to boost blood stem cells in aplastic anemia
A new drug approach aims to help people with idiopathic aplastic anemia by stimulating blood-forming stem cells through mechanisms that may not depend on traditional pathways.
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Iron-deficiency anemia treatment plan for adults undergoing surgery
Aimed at adults having surgery, this project tests a practical plan to identify and treat iron deficiency anemia to improve recovery and reduce complications.
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What anemia does to brain blood flow and oxygen use
A study at Vanderbilt will look at how anemia changes tiny blood flow in the brain and how that affects oxygen use, to understand why strokes or brain injury may occur in people with anemia.
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How cells detect DNA damage and activate ATR, ATM, and Fanconi anemia repair systems
Researchers are using high-resolution structural imaging to show how key repair proteins sense DNA damage, with relevance for people whose cancers come from DNA repair defects.
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Ischemic and neurometabolomic contributors to brain health in sickle cell anemia
This grant studies why people with sickle cell anemia have cognitive problems, looking at brain blood flow, oxygen use, and other brain signals to understand who is at risk and why.
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New approach to severe malaria-related anemia using the body’s antioxidant balance
This project explores whether boosting a key antioxidant in red blood cells can help prevent or reduce severe anemia in people with malaria.
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In vivo gene therapy for Fanconi anemia
A patient-focused overview of a potential in vivo gene therapy approach to correct Fanconi anemia, aiming to reduce the need for donor transplants.
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RBC-bound cell-free DNA as a predictor of acute anemia in sickle cell disease
Aims to understand whether DNA released from cells in the blood can forecast sudden drops in hemoglobin in people with sickle cell disease.
Related topics
Quick answers
How many Anemia clinical trials are recruiting right now?
58, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 45 countries. The most sites are in United States (16 trials), China (11 trials), Germany (7 trials), France (6 trials), Spain (6 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 9, Phase 3: 4, Phase 4: 4, Phase 1/2: 3. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.