Investigating blood pressure levels after heart surgery and their link to kidney injury
Official title: Evaluating the association between mean arterial blood pressure through the first 24 hours after cardiac surgery and postoperative acute kidney injury
Funded at Vanderbilt University Medical Center · NIH-10877008 · Data updated 2026-11-12
This study is looking at how blood pressure in the first day after heart surgery might affect the chances of developing kidney problems, and it's for patients who have just had heart surgery to help find the best blood pressure levels to keep them safe.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $49,999 |
| NIH project number | 5R03HS029218-02 |
| Project ID | NIH-10877008 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults undergoing cardiac surgery who are at risk for postoperative complications.
✕Less likely to help
Patients who are not undergoing cardiac surgery or those with pre-existing severe kidney disease may not benefit from this research.
What this research studies
This research focuses on understanding how mean arterial blood pressure (MAP) during the first 24 hours after cardiac surgery affects the risk of acute kidney injury (AKI). By analyzing existing data on blood pressure levels in patients post-surgery, the study aims to identify the optimal MAP target that could minimize the risk of AKI. The research will evaluate different MAP ranges to determine their association with kidney injury and other potential complications. This could lead to improved guidelines for managing blood pressure in the critical postoperative period.
Why it matters
Potential benefit: If successful, this research could lead to better management of blood pressure after cardiac surgery, potentially reducing the incidence of acute kidney injury and improving patient outcomes.
How similar studies have gone: Previous research has indicated that managing blood pressure effectively in the postoperative period can influence outcomes, suggesting that this approach may yield significant insights.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Mcilroy, David Richard — Vanderbilt University Medical Center
- Study coordinator: Mcilroy, David Richard
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.