Intrapleural ropivacaine after heart surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, double-blind, placebo-controlled Phase 4 trial comparing intrapleural ropivacaine infusion to saline in adults having cardiac surgery with planned opening of the pleural cavities. After median sternotomy and placement of pleural drains, participants receive either ropivacaine or 0.9% NaCl through the drains for the early postoperative period. Outcomes include postoperative pain, opioid consumption, quality of recovery, and safety/complications related to the local anesthetic. The trial is conducted at university and regional hospital sites in Russia.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Scheduled cardiac surgery using a standard median sternotomy.
* Planned opening of the pleural cavities.
* Age more than 18 years.
* Signed informed consent to participate in the study.

Exclusion Criteria:

* Contraindications for ropivacaine
* Redo surgery

Where it's running

• Saint-Petersburg university hospital
  Saint Petersburg, Russia Recruiting
• Primorskiy general hospital #1
  Vladivostok, Russia Recruiting

Study contacts

• Study coordinator: Sergey M Efremov, MD, PhD
• Email: efremovsergm@gmail.com
• Phone: 79137946090

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.