Evaluating a noninvasive method to measure blood flow in cardiac surgery patients
The Consistency of Tracking Changes of Cardiac Output by Carotid Doppler Blood Flow and Thermodilution Technique in Cardiac Surgery Patients
This study is testing a new, noninvasive way to measure blood flow during heart surgery to see if it works as well as the traditional method for patients on ventilators.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Shanghai Zhongshan Hospital Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Trial ID | NCT05944146 on ClinicalTrials.gov |
What this trial studies
This study aims to assess the consistency of cardiac output measurements obtained through a continuous carotid Doppler technique compared to the traditional thermodilution method in adult cardiac surgery patients. The research focuses on patients who are mechanically ventilated and have thermodilution monitoring in place. By utilizing noninvasive carotid blood flow measurements, the study seeks to provide a simpler and safer alternative for estimating cardiac output and related parameters during surgery. The effectiveness of this technique will be evaluated through interventions such as passive leg raising and Dobutamine administration.
Who should consider this trial
Good fit: Ideal candidates for this study are adult patients undergoing cardiac surgery who are on mechanical ventilation and have thermodilution monitoring.
Not a fit: Patients with life-threatening arrhythmias, severe valve regurgitation, or those with a left ventricular ejection fraction less than 30% may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a safer, noninvasive method for monitoring cardiac output in patients undergoing cardiac surgery.
How similar studies have performed: While few studies have evaluated the consistency of the carotid Doppler technique in cardiac surgery patients, the approach has shown promise in other cardiovascular disorders.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * adult cardiac surgery patients * with thermodilution technique monitoring * mechanical ventilation Exclusion Criteria: * life threatening arrhythmia * severe valve regurgitation * left ventricular ejection fraction less than 30% * patients with mechanical circulatory support
Where this trial is running
Shanghai, Shanghai Municipality
- Zhongshan hospital Fudan University — Shanghai, Shanghai Municipality, China (Recruiting)
Study contacts
- Study coordinator: Guang-wei Hao
- Email: hao.guangwei@zs-hospital.sh.cn
- Phone: 02164041990
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.