Clinical trial Recruiting at 1 site Interventional Ages 18 to 80

Evaluating a noninvasive method to measure blood flow in cardiac surgery patients

Official title: The Consistency of Tracking Changes of Cardiac Output by Carotid Doppler Blood Flow and Thermodilution Technique in Cardiac Surgery Patients

Run by Shanghai Zhongshan Hospital · NCT05944146 · Data updated 2026-11-12

This study is testing a new, noninvasive way to measure blood flow during heart surgery to see if it works as well as the traditional method for patients on ventilators.

More Cardiac Surgery trials

Quick facts

Study typeInterventional
Ages18 Years to 80 Years
SexAll
Enrollment200 (estimated)
SponsorShanghai Zhongshan Hospital
Academic / other
Locations1 site (Shanghai, Shanghai Municipality)
StatusRecruiting
StartedMay 31, 2023
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedJuly 13, 2023
Trial IDNCT05944146 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adult patients undergoing cardiac surgery who are on mechanical ventilation and have thermodilution monitoring.

Probably not a fit

Patients with life-threatening arrhythmias, severe valve regurgitation, or those with a left ventricular ejection fraction less than 30% may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess the consistency of cardiac output measurements obtained through a continuous carotid Doppler technique compared to the traditional thermodilution method in adult cardiac surgery patients. The research focuses on patients who are mechanically ventilated and have thermodilution monitoring in place. By utilizing noninvasive carotid blood flow measurements, the study seeks to provide a simpler and safer alternative for estimating cardiac output and related parameters during surgery. The effectiveness of this technique will be evaluated through interventions such as passive leg raising and Dobutamine administration.

Why it matters

Potential benefit: If successful, this study could provide a safer, noninvasive method for monitoring cardiac output in patients undergoing cardiac surgery.

How similar studies have gone: While few studies have evaluated the consistency of the carotid Doppler technique in cardiac surgery patients, the approach has shown promise in other cardiovascular disorders.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* adult cardiac surgery patients
* with thermodilution technique monitoring
* mechanical ventilation

Exclusion Criteria:

* life threatening arrhythmia
* severe valve regurgitation
* left ventricular ejection fraction less than 30%
* patients with mechanical circulatory support

Where it's running

  • Zhongshan hospital Fudan University
    Shanghai, Shanghai Municipality, China
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.