Evaluating a noninvasive method to measure blood flow in cardiac surgery patients
Official title: The Consistency of Tracking Changes of Cardiac Output by Carotid Doppler Blood Flow and Thermodilution Technique in Cardiac Surgery Patients
Run by Shanghai Zhongshan Hospital · NCT05944146 · Data updated 2026-11-12
This study is testing a new, noninvasive way to measure blood flow during heart surgery to see if it works as well as the traditional method for patients on ventilators.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Shanghai Zhongshan Hospital Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Status | Recruiting |
| Started | May 31, 2023 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | July 13, 2023 |
| Trial ID | NCT05944146 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adult patients undergoing cardiac surgery who are on mechanical ventilation and have thermodilution monitoring.
✕Probably not a fit
Patients with life-threatening arrhythmias, severe valve regurgitation, or those with a left ventricular ejection fraction less than 30% may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to assess the consistency of cardiac output measurements obtained through a continuous carotid Doppler technique compared to the traditional thermodilution method in adult cardiac surgery patients. The research focuses on patients who are mechanically ventilated and have thermodilution monitoring in place. By utilizing noninvasive carotid blood flow measurements, the study seeks to provide a simpler and safer alternative for estimating cardiac output and related parameters during surgery. The effectiveness of this technique will be evaluated through interventions such as passive leg raising and Dobutamine administration.
Why it matters
Potential benefit: If successful, this study could provide a safer, noninvasive method for monitoring cardiac output in patients undergoing cardiac surgery.
How similar studies have gone: While few studies have evaluated the consistency of the carotid Doppler technique in cardiac surgery patients, the approach has shown promise in other cardiovascular disorders.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * adult cardiac surgery patients * with thermodilution technique monitoring * mechanical ventilation Exclusion Criteria: * life threatening arrhythmia * severe valve regurgitation * left ventricular ejection fraction less than 30% * patients with mechanical circulatory support
Where it's running
-
Zhongshan hospital Fudan University
Shanghai, Shanghai Municipality, China Recruiting
Study contacts
- Study coordinator: Guang-wei Hao
- Email: hao.guangwei@zs-hospital.sh.cn
- Phone: 02164041990
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.