Non‑drug, non‑invasive treatments given before heart surgery to protect the brain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized controlled trial, adults aged 18–80 who are scheduled for elective cardiac surgery and identified as high risk for postoperative neurological complications will be assigned to receive active remote ischemic preconditioning and transcranial electrical stimulation or a sham/no-treatment control before surgery. Researchers will monitor for perioperative neurological outcomes such as stroke, delirium, and cognitive decline, and will collect safety data on the two non‑invasive interventions. The interventions are non‑pharmacological and applied prior to the operative period, with follow-up during the immediate postoperative phase. Results will compare rates of neurological complications and adverse events between the groups.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age range: 18-80 years old;
2. Surgical patients with heart disease;
3. Elective surgery;
4. Patients identified as high-risk for postoperative neurological complications; Previous stroke history; Moderate to severe stenosis of the head and neck arteries was evaluated;
5. Be able to understand and comply with the requirements of clinical trial protocols, and voluntarily sign informed consent forms.

Exclusion Criteria:

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Where it's running

• Department of Neurology, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing,
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Yao Feng, M.D.
• Email: fengyao_dr@sina.com
• Phone: 18810643595

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.