Reducing the need for reintubation in high-risk cardiac surgery patients using high-flow nasal cannula.

Reducing Reintubation Risk in High-Risk Cardiac Surgery Patients with High-Flow Nasal Cannula -the "I-CAN" study

NIH-funded research Vanderbilt University Medical Center · NIH-10819218

This study is looking at how well high-flow nasal cannula therapy can help prevent the need for reintubation in patients who have just had heart surgery, especially those with other health problems, to improve their recovery and care after the operation.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center NIH-funded
Lab location1 site (Nashville, United States)
Project IDNIH-10819218 on NIH RePORTER

What this research studies

This research investigates the effectiveness of high-flow nasal cannula therapy in preventing reintubation among patients who have undergone cardiac surgery. The study focuses on high-risk individuals, particularly those with multiple health issues, and aims to identify strategies that can reduce the likelihood of needing to reinsert a breathing tube after surgery. By utilizing advanced clinical informatics and pragmatic trial design, the research seeks to gather data that can inform better postoperative care practices. Patients will be monitored closely to assess outcomes related to reintubation rates and overall recovery.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who are undergoing high-risk cardiac surgery and may have multiple comorbidities.

Not a fit: Patients who are not undergoing cardiac surgery or those with minimal health risks may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the risk of reintubation, leading to improved recovery outcomes and lower healthcare costs for patients undergoing cardiac surgery.

How similar studies have performed: Previous research has shown promising results in using high-flow nasal cannula therapy in various settings, suggesting potential for success in this novel application for cardiac surgery patients.

Where this research is happening

Nashville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.