Improving anesthesia practices to prevent kidney injury after heart surgery
Official title: Cardiac sURgery anesthesia Best practices to reduce Acute Kidney Injury (CURB-AKI)
Funded at University of Michigan at Ann Arbor · NIH-11163225 · Data updated 2026-11-12
This study is looking at how better anesthesia techniques during heart surgery can help protect your kidneys and reduce the chances of kidney problems afterward, so if you're having heart surgery, this research is all about making your recovery safer and healthier.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | July 1, 2022 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $642,037 |
| NIH project number | 5R01DK133226-04 |
| Project ID | NIH-11163225 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who are scheduled to undergo cardiac surgery.
✕Less likely to help
Patients who are not undergoing cardiac surgery or those with pre-existing severe kidney disease may not benefit from this research.
What this research studies
This research investigates how best practices in anesthesia during cardiac surgery can reduce the risk of acute kidney injury (AKI) in patients. By analyzing detailed data from the intraoperative and early ICU periods, the study aims to identify specific factors that contribute to AKI and develop strategies to mitigate these risks. The approach involves advanced analytics to process thousands of physiological and clinical data points for each patient, allowing for a more tailored and effective intervention. Patients undergoing cardiac surgery will be monitored closely to assess the impact of these improved practices on kidney health.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of acute kidney injury in cardiac surgery patients, leading to better recovery outcomes and lower healthcare costs.
How similar studies have gone: Previous studies have shown promise in using advanced analytics to improve surgical outcomes, but this specific approach to preventing AKI in cardiac surgery is relatively novel.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Mathis, Michael Robert — University of Michigan at Ann Arbor
- Study coordinator: Mathis, Michael Robert
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.