Bilateral serratus posterior superior intercostal plane block for pain after on‑pump open‑heart surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults undergoing elective on‑pump median sternotomy are assigned to receive either an ultrasound‑guided bilateral SPSIP block or a sham block, and all receive IV morphine patient‑controlled analgesia after surgery. Pain scores, cumulative morphine consumption, quality of recovery, and opioid‑related side effects are recorded within the first 24 hours after surgery. The SPSIP block is a recently described fascial plane technique that may provide broad thoracic dermatomal coverage and an alternative to neuraxial approaches in anticoagulated patients. Standard exclusion criteria include chronic opioid use, significant organ dysfunction, coagulation disorders, severe psychiatric illness, pregnancy, and emergency or redo surgeries.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 18-80 undergoing elective on-pump open-heart surgery via median sternotomy.
* American Society of Anesthesiologists (ASA) classification II-III patients.
* Patients who can use PCA.
* Patients who will sign the informed consent form.

Exclusion Criteria:

* History of opioid use for more than four weeks
* Chronic pain syndromes
* Patients with a history of local anesthetic or opioid allergy, hypersensitivity
* Alcohol and drug addiction
* Conditions where regional anesthesia is contraindicated
* Failure in the dermatomal examination performed after the block
* Emergency surgeries and redo surgeries.
* Individuals with obstructive sleep apnea.
* Left ventricular ejection fraction less than 30%.
* Patients with severe psychiatric illnesses (such as psychosis, dementia) that limit cooperation with verbal numerical pain scales.
* Pregnant and breastfeeding patients.
* Hematological disorders.
* Significant impairment in the function of a major organ (e.g., severe hepatic or renal disease). • Patients who cannot be extubated within the first 6 hours postoperatively.

Where it's running

• Burhan Dost
  Samsun, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Burhan Dost
• Email: burhandost@hotmail.com
• Phone: 05327042493

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.