Condition
Acute Postoperative Pain clinical trials and research
As of November 12, 2026, Find a Trial lists 8 Acute Postoperative Pain clinical trials that are recruiting, at sites in 6 countries (most in United States (2), Colombia (2), Turkey (Türkiye) (1)). 1 was first registered in the last 30 days. By phase: Phase 4 (2), Phase 1/2 (1), Phase 3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 8Clinical trials
- 1New in 30 days
- 6Countries
Newest Acute Postoperative Pain clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| CYT-1010 in healthy volunteers and after third molar extraction | Phase 1/2 | Salt Lake City, Utah | Recruiting | Oct 29, 2026 |
| Pharmacogenetics of Tramadol Pain Control in Postoperative Care | — | Medellín, Antioquia | Recruiting | Sep 9, 2026 |
| Visual Analog Scale–Guided Multimodal Pain Plan After Posterior Rib Remodeling | — | Bogotá | Recruiting | Sep 8, 2026 |
| TENS for acute pain after VATS surgery | — | Kaohsiung City, Kaohsiung City | Recruiting | Jul 29, 2026 |
| DIPB vs SIFIB for pain control after total hip replacement | — | Sivas, Sivas and 1 other locations | Recruiting | Mar 5, 2026 |
| Buprenorphine via PCA vs oxycodone for pain after VATS | Phase 4 | Zabrze, Silesian Voivodeship | Recruiting | Feb 25, 2026 |
| Continuous versus single adductor canal nerve block for outpatient total knee replacement | Phase 4 | La Jolla, California | Recruiting | Jan 20, 2025 |
| Using non-steroidal anti-inflammatory drugs for pain management after heart surgery | Phase 3 | Amiens | Recruiting | Apr 24, 2024 |
All recruiting trials (8)
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CYT-1010 in healthy volunteers and after third molar extraction
This trial tests CYT-1010, at single rising doses, for safety and tolerability in healthy adults and in people experiencing pain after removing wisdom teeth.
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Pharmacogenetics of Tramadol Pain Control in Postoperative Care
This study tests whether CYP2D6 genetic differences affect how well tramadol works and its side effects in people recovering from surgery who all receive the same tramadol pump.
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Visual Analog Scale–Guided Multimodal Pain Plan After Posterior Rib Remodeling
This study tests a pain management plan guided by a 0–10 pain score to see if it keeps postoperative pain low after posterior rib remodeling with osteosynthesis.
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TENS for acute pain after VATS surgery
A randomized, sham-controlled test will see if Transcutaneous Electrical Nerve Stimulation helps with acute pain after VATS surgery in adults and older teens.
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DIPB vs SIFIB for pain control after total hip replacement
This will test whether the Deep Iliacus Plane Block (DIPB) or the Suprainguinal Fascia Iliaca Block (SIFIB) gives better pain relief and less leg weakness for adults having elective total hip replacement.
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Buprenorphine via PCA vs oxycodone for pain after VATS
This trial tests whether intravenous buprenorphine given through a patient-controlled pump provides better and safer pain relief than intravenous oxycodone after video-assisted thoracic surgery in adults.
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Continuous versus single adductor canal nerve block for outpatient total knee replacement
This test checks whether adding a 5-day continuous adductor canal nerve block to the usual single injection lowers pain and opioid use after outpatient total knee replacement.
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Using non-steroidal anti-inflammatory drugs for pain management after heart surgery
This study tests if using non-steroidal anti-inflammatory drugs can safely help manage pain after heart surgery without causing complications.
Related topics
Quick answers
How many Acute Postoperative Pain clinical trials are recruiting right now?
8, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 6 countries. The most sites are in United States (2 trials), Colombia (2 trials), Turkey (Türkiye) (1 trial), Taiwan (1 trial), Poland (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 2, Phase 1/2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.