Sponsor or institution
Clinical trials and research at Fondazione IRCCS Policlinico San Matteo di Pavia
As of November 12, 2026, Find a Trial lists 96 clinical trials run by Fondazione IRCCS Policlinico San Matteo di Pavia that are recruiting, at sites in 6 countries (most in Italy (96), Switzerland (2), Germany (1)). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 96Clinical trials
- 6Countries
Newest trials
All recruiting trials (96)
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AirGo Respiratory Monitoring During Lung Resection
Patients undergoing lung resection will wear the AirGo device to continuously monitor breathing before and after surgery to see if it helps track ventilation alongside standard checks.
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Experiences After Risk-Reducing Mastectomy in BRCA1/2 Carriers
This study asks women with BRCA1/2 or related variants who had risk-reducing mastectomy to share their experiences and satisfaction to see what factors are connected to how happy they are with the outcome.
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Natural history of eosinophilic esophagitis in adults and children
This observational study tests how eosinophilic esophagitis progresses over time in people 5 years and older to understand symptoms and outcomes.
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COVID-19 Registry at San Matteo (SMACORE) - patient-matching observational registry
This registry tests how COVID-19 patients are being treated and progress across San Matteo in Pavia to understand patterns and outcomes.
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Registry of Transcatheter Aortic Valve Treatments at a Italian Center
This registry tests how safe and effective transcatheter valve procedures are in adults with severe aortic stenosis treated at a single Italian center.
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Systemic Vasculitis Prognosis and Outcome
This study follows patients suspected or diagnosed with systemic vasculitis over 10 years to see how their disease progresses and what factors predict outcomes.
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Monitoring remission and planned drug tapering in early rheumatoid arthritis
This registry will follow adults with early rheumatoid arthritis who are in stable remission on conventional DMARDs to see if tapering or stopping those drugs is safe and how often disease returns.
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Pulmonary hypertension in adults on chronic hemodialysis: prevalence, causes, and prognosis
This study will test how common pulmonary hypertension is and what causes it in adults on long-term hemodialysis, using heart imaging, catheter measurements, and blood markers to see who is at higher risk.
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Renal embolization with EVOH for adults on dialysis with ADPKD
This study tests whether blocking blood flow to very large polycystic kidneys with the liquid embolic EVOH can shrink kidney size and reduce symptoms in adults on dialysis with ADPKD.
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Immune response to Shingrix in adults with psoriasis or myelofibrosis on immunomodulatory therapy
This project will test how well the Shingrix vaccine triggers immune responses in adults with psoriasis or myelofibrosis who are or are not taking immunomodulating drugs.
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Comprehensive registry of lymphoproliferative disorders and outcomes
This project will test how treatments, patient health, and genetic features affect 10-year survival in adults with lymphoproliferative disorders.
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How patient factors and surgical technique affect leftover adenoid tissue after adenoidectomy
This project will try to see if children's characteristics and the way surgeons remove adenoids affect how much adenoid tissue is left after adenoidectomy.
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Prosthetic joint surgery in adults with congenital bleeding disorders (Italy)
This project collects past and future data on prosthetic joint surgery in adults with congenital bleeding disorders to see which patient, surgical, and treatment factors relate to outcomes.
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Lung MRI for non-cancer lung disease (early IPF)
This project will try using advanced lung MRI (with bronchoalveolar lavage when safe) to look for imaging and molecular signs in people with early-stage idiopathic pulmonary fibrosis (IPF).
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Lung MRI to identify immune patterns in non-small cell lung cancer
This will see if combining different MRI measurements of the lung can create imaging signatures that identify immune-related patterns in people with primary non-small cell lung cancer.
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Immune and viral markers that predict HCMV passing to the baby during pregnancy
This project will see if immune and viral markers in pregnant women with recent primary HCMV infection can predict whether the virus will be passed to the fetus.
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Preventing infections with vaccines in bone marrow and solid organ transplant patients
This project will try a vaccine-focused care pathway to increase vaccine coverage and see if it lowers infections and deaths in people getting solid organ or bone marrow transplants.
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High-yield method for extracting hematopoietic stem cells from cord blood
This research tests whether a new biocompatible liquid, with or without low-dose ozone treatment, can extract more viable hematopoietic stem cells from donated umbilical cord blood than standard centrifugation.
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How the IGLV1-44 light chain causes AL amyloidosis and POEMS
This project tests whether specific IGLV1-44 light‑chain sequences drive AL amyloidosis and POEMS and whether nanobodies can recognize and stabilize those light chains in adults with AL amyloidosis, POEMS, or multiple myeloma.
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How N-glycosylation of light chains affects AL amyloidosis diagnosis and treatment
This project will test whether a sugar modification called N-glycosylation on immunoglobulin light chains helps cause disease or changes how AL amyloidosis and related monoclonal gammopathies behave in adults.
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Aspergillus spread among adults in a hematology ward
The team will see if Aspergillus in the ward environment and in patients' noses is linked to later infections or worse symptoms in adults admitted to the hematology ward.
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Oxidative stress markers in adults with type 1 diabetes versus LADA.
This project will see if blood markers of oxidative stress differ between adults with type 1 diabetes and adults with LADA.
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Italian validation of the Braden QD pressure-injury risk scale for newborns in the NICU
This project will test whether the Italian Braden QD Scale can reliably identify newborns in the NICU who are at risk of developing pressure injuries.
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Measuring the shape and strength of the ascending aorta in patients having heart surgery
We will test whether direct measurements of the aortic wall's mechanical properties taken during heart surgery can better characterize rupture or dissection risk in people with ascending aortic aneurysm by comparing them to patients undergoing heart transplantation without known aortic disease.
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CDK4/6 drugs for older women with breast cancer
This project will test whether CDK4/6 drugs work as well and are as safe in women aged 70 and older with breast cancer as they are in younger women, using real-world medical records and follow-up.
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How autoimmune atrophic gastritis develops and presents over time
This project will follow adults with autoimmune atrophic gastritis to see how the disease progresses and affects the stomach, nutrient absorption, and overall health.
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Personalized immunological score to predict severe infections in transplant and immunocompromised patients
This project will test whether a personalized immunological score can predict serious infections in transplant and other immunocompromised patients and help tailor their care.
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Local registry of central nervous system infections
This registry will collect health and treatment information from people admitted with central nervous system infections at a Pavia hospital to see if patterns in presentation, timing, treatments, and outcomes can be identified.
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Neonatal Echovirus 11 infections in Italy: virological, genomic and clinical insights
This project will test whether sequencing virus samples from newborns with enterovirus infections, especially Echovirus 11, helps explain how the virus causes illness in the first weeks of life.
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San Matteo Endocarditis Registry (STEADY)
This registry collects health and treatment information from people diagnosed with infective endocarditis at San Matteo to better understand their care and outcomes.
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Parvovirus B19 in pregnancy and its effects on the baby
This project follows pregnant women who get parvovirus B19 and their babies to see how often the infection causes problems for the fetus or newborn.
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Immune‑blot band patterns in inactive liver cysts from cystic echinococcosis
This will test whether immunoblot band patterns differ between treated and untreated adults with inactive echinococcal cysts in the liver.
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Recombinant shingles vaccine for frail and immunocompromised adults
This project will test whether a recombinant shingles (herpes zoster) vaccine produces protective immune responses and is safe in frail adults with weakened immune systems.
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Breast radiotherapy using active breath hold to reduce heart exposure
This project will see if using an Active Breathing Coordinator (ABC) for deep inspiration breath hold reduces radiation dose to the heart in adults with stage I–III breast cancer receiving radiotherapy.
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Postoperative care after head and neck free flap reconstruction: ICU versus Otolaryngology ward
This study will see if patients who go to the ICU after head and neck free flap reconstruction have similar complication rates, flap success, and hospital stays as patients cared for on an Otolaryngology specialty ward.
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Nasal immune responses to respiratory viruses in immunocompromised and healthy adults
See how nasal immune responses to respiratory viruses differ between immunocompromised adults and healthy adults.
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Comparing two supplements (Cynacol vs Metacol) for lowering LDL cholesterol in mild high cholesterol
This test will see if the supplement Cynacol lowers LDL cholesterol more than Metacol in adults aged 35–70 with mild high LDL (115–190 mg/dL).
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Pavia chronic heart failure patient registry
This registry will collect health and treatment information from adults with chronic heart failure in Pavia to see patterns and outcomes over time.
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Characterizing T-cell responses to arbovirus infections using ELISpot tests
This project will test whether ELISpot blood assays can detect T-cell immune responses in adults with suspected arbovirus infections.
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Predicting brain-related causes of vertigo, dizziness, and unsteadiness in the emergency department
This research will test whether a bedside exam algorithm used by emergency doctors can tell if an adult's vertigo, dizziness, or unsteadiness is caused by a brain problem.
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Machine learning to distinguish EGPA from HES
This project will test whether machine learning applied to clinical, lab, and instrument data can help tell EGPA apart from HES and predict how patients respond to treatment.
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Ambispective registry of adults with lung cancer at Policlinico San Matteo
This registry will collect medical data from adults with lung cancer treated at Policlinico San Matteo from 2019 to 2035 to see how treatments, side effects, and survival compare in real-world care.
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Single-cell immune profiling to distinguish responders and non-responders to immunotherapy in advanced liver cancer
This research will see if single-cell RNA patterns in blood immune cells can predict which patients with advanced liver cancer respond to immunotherapy.
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Using PCR to detect malaria, Leishmania, and Pneumocystis infections
This project will test whether PCR can more quickly and accurately detect malaria, Leishmania, and Pneumocystis in patient samples.
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Bedside measurement of lung collapse and reopening in people on invasive mechanical ventilation
This project will try using ventilator-recorded pressure and volume data to measure how much lung tissue opens with inhalation and then collapses again with exhalation in people on passive invasive mechanical ventilation for acute respiratory failure.
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Early prediction of lung injury in very preterm infants using EIT and lung ultrasound
This project will test whether bedside Electrical Impedance Tomography (EIT) and lung ultrasound in stable preterm babies on non-invasive breathing support can spot uneven lung ventilation that predicts severe BPD or death by 36 weeks postmenstrual age.
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Euglycem® plus recommended diet to lower blood sugar in people with dysglycemia
This will see if taking the supplement Euglycem® alongside a recommended diet lowers fasting blood sugar after three months in adults with dysglycemia.
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Venetoclax blood levels and treatment toxicity during hypomethylating-agent combinations for AML in remission
This study will see if venetoclax blood levels are linked to side effects in people with AML who are in remission and receiving hypomethylating agents plus venetoclax.
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Finding genes linked to familial pulmonary fibrosis
This project will test whether analyzing the genes of adults from families with multiple cases of pulmonary fibrosis can uncover genetic causes and help guide diagnosis and family counseling.
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Understanding the tumor microenvironment in children's solid tumors to improve adoptive cell therapy
We will analyze tumor samples from children with solid tumors to see if features of the tumor environment can help guide better adoptive T cell therapy.
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Inherited risk factors for myeloproliferative neoplasms
This project will test whether inherited (germline) genetic changes raise the risk of myeloproliferative neoplasms in people diagnosed before age 27 or with multiple affected relatives.
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First-line nivolumab plus ipilimumab with short-course chemotherapy for metastatic non-small cell lung cancer
This project will collect real-world data to see if nivolumab plus ipilimumab combined with a short course of platinum chemotherapy works well as first-line treatment for adults with metastatic non-small cell lung cancer who do not have EGFR or ALK alterations.
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Neonatal BNP and metabolic syndrome risk in adolescents
This project will see if newborn BNP levels and early heart ultrasound measurements are linked to metabolic syndrome in adolescents who had those tests as infants.
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Impact of uterine fibroids on pelvic floor function
This observational study will see if uterine fibroids are linked to urinary and other pelvic floor symptoms in women with symptomatic intramural or subserosal fibroids who are scheduled for hysterectomy or myomectomy.
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Pavia registry for people with primary cutaneous T-cell lymphoma
This registry collects past and future medical information from people with primary cutaneous T-cell lymphoma who are seen at the Dermatology Clinic in Pavia to better understand treatments and outcomes.
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Prehospital extracorporeal CPR program for refractory cardiac arrest in Pavia province
This program will try extracorporeal CPR (eCPR) before hospital arrival to see if it restores blood flow sooner and improves survival and brain recovery for adults 18–70 with witnessed refractory out-of-hospital cardiac arrest in the Pavia province.
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Tracking mastocytosis from childhood to adulthood
This hospital registry will collect clinical, laboratory, and genetic information from children and adults with cutaneous or systemic mastocytosis seen in Pavia to see how the disease changes over time and what predicts outcomes.
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Acupuncture for pain after total knee replacement
This project will try acupuncture to reduce short-term pain, opioid use, and inflammation after elective total knee replacement in adults.
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Investigating nutrition and eating habits in athletic women and their effect on menstrual function
This study is testing how the eating habits and nutrition knowledge of active women aged 16-30 affect their menstrual health, especially for those with certain menstrual issues.
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In-hospital registry for patients with severe trauma
This study is setting up a system to track and gather information on patients with severe injuries at a hospital to improve their care and outcomes.
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Investigating quality of life with different hormonal contraceptives in women
This study tests how different types of hormonal birth control affect mood and sexual health in women to see which options might improve their overall quality of life.
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Comparing surgical and endoscopic treatments for high-risk acute gallbladder inflammation
This study is testing whether surgery or a less invasive procedure works better for high-risk patients with severe gallbladder inflammation.
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Comparing two methods for treating acute gallbladder inflammation with potential bile duct stones
This study tests two different ways to treat acute gallbladder inflammation in patients who might have bile duct stones to see which method works better.
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Evaluating inhalable Imatinib for treating pulmonary hypertension and lung fibrosis
This study is testing a new inhalable medication called XHALIP to see if it can help people with pulmonary hypertension and lung fibrosis feel better by improving their lung health.
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Immunotherapy for treating SARS-CoV-2 and liver tumors
This study is testing new immune treatments to see if they can help fight both COVID-19 and liver tumors.
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Validation of a scoring system to predict mortality after gallbladder surgery for acute cholecystitis
This study is testing a new scoring system to see if it can help predict the risk of death within 30 days after gallbladder surgery for people with acute cholecystitis.
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Psychological support program for patients with hereditary transthyretin amyloidosis
This study is testing a new psychological support program for patients and their families dealing with hereditary transthyretin amyloidosis to see if it helps reduce feelings of anxiety and depression over a year.
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Impact of Stem Cell Donation on Donors' Health
This study looks at how donating stem cells affects the health and well-being of both related and unrelated donors over time.
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Collecting blood and tissue samples from patients with primary liver cancer
This study is collecting blood and tissue samples from patients with primary liver cancer to help researchers find new treatments for the disease.
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Long-term follow-up of colitis caused by immune checkpoint inhibitors
This study looks at patients who have developed colitis from immune checkpoint inhibitors to better understand the condition and improve how it's treated.
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Investigating the effects of mesenchymal stromal cell vesicles on blood cell development in myelofibrosis patients
This study is testing how special cells from patients with myelofibrosis affect the growth of blood cells to see if they behave differently than those from healthy people.
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Evaluating human neuron activity using brain tissue slices.
This study is testing how human brain cells work by using slices of brain tissue from surgery to see how they respond to different signals and if their behavior changes in disease.
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Exploring genetic factors in malignant pleural mesothelioma
This study is trying to see if certain genetic factors make people more likely to develop malignant pleural mesothelioma after being exposed to asbestos.
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Evaluating the impact of post-operative radiotherapy on high-grade skin cancer
This study is testing if getting radiation therapy after surgery helps people with high-grade skin cancer live longer and have fewer recurrences compared to those who don't get the treatment.
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Combining topical hyaluronic acid with high-concentration oxygen therapy for menopausal symptoms
This study is testing if a treatment that combines a special gel and high-concentration oxygen can help postmenopausal women, including those who had breast cancer, feel better by reducing vaginal dryness and other symptoms.
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Research on factors predicting IVF outcomes in women with autoimmune diseases
This study is trying to find out what factors can help predict how well in vitro fertilization (IVF) works for women with autoimmune diseases.
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Assessing the impact of antibiotic therapy on MRSA in hospitalized children
This study is trying to see how antibiotic treatment affects the presence of MRSA in hospitalized children aged 1 to 16 years.
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Observing pelvic floor changes during pregnancy and after childbirth
This study looks at how pregnancy and childbirth affect the pelvic floor muscles and support structures in women to better understand pelvic floor issues.
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Improving diagnosis of vestibulodynia using omics approaches
This study is trying to find better ways to diagnose vestibulodynia in women aged 18 to 50 by looking at biological samples to see if there are specific markers that can help identify this painful condition.
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Investigating multiple HPV infections and their role in cervical changes
This study looks at how common multiple high-risk HPV infections are in people with abnormal cervical tests to see how they might affect cervical health.
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Monitoring Treosulfan in Children Undergoing Stem Cell Transplant
This study is testing how Treosulfan works in children getting a stem cell transplant to see if it can help them have better outcomes with fewer side effects.
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Understanding coping strategies in children with cancer and their parents
This study looks at how children with cancer and their parents handle the illness together to see what helps them cope better during treatment.
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Evaluating genetic causes of out-of-hospital cardiac arrest
This study is trying to find out if genetic heart diseases are common in younger people who have a cardiac arrest outside of the hospital and to see how this might affect their family members.
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Observational study on treatments for relapsed multiple myeloma
This study looks at how well certain approved treatments work for adults with relapsed multiple myeloma who have already tried specific therapies.
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Network for early diagnosis and management of AL amyloidosis in Italy
This study is trying to set up a network in Italy to help doctors find AL amyloidosis earlier in patients who are at risk, so they can get treatment sooner and improve their health.
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Registry to monitor malnutrition in cancer patients
This study is trying to see how tracking nutrition in newly diagnosed or treated cancer patients can help improve their health and quality of life.
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Evaluation of heart health in patients with ATTR amyloidosis on tafamidis treatment
This study looks at how tafamidis treatment affects heart health in patients with ATTR amyloidosis by checking their heart rhythm and other health needs every six months.
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Registry for diagnosing and managing AL amyloidosis in Europe
This study is creating a registry to help doctors better diagnose and manage AL amyloidosis in Europe by collecting patient information and samples to learn more about the disease.
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Nutritional support for gynecologic cancer patients undergoing chemotherapy
This study tests if adding a special nutritional supplement to the standard care can help women with gynecologic cancer undergoing chemotherapy maintain muscle mass and improve their treatment outcomes.
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Using Stellate Ganglion Block to Treat Arrhythmic Storm
This study is testing if a special nerve block can help people having a severe heart rhythm problem called arrhythmic storm by reducing the number of shocks they need from a defibrillator.
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Registry for patients with ATTR amyloidosis
This study is creating a detailed registry for people with ATTR amyloidosis to track their health over time and help doctors understand the disease better.
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Using immunonutrition to enhance immunotherapy effectiveness in lung cancer patients
This study tests if giving special nutritional supplements to lung cancer patients receiving immunotherapy can help their treatment work better.
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Evaluating gastrointestinal eosinophilic disorders in children
This study looks at how common eosinophilic gastrointestinal disorders are in children to help improve understanding and treatment of these conditions.
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Registry for patients with AL amyloidosis
This study is collecting information from people with AL amyloidosis to better understand the disease and how it changes over time.
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Improving tolerance to chemoradiotherapy in head and neck cancer patients with nutritional support
This study is testing if a special nutritional drink can help people with head and neck cancer handle their chemoradiotherapy better than a regular nutritional drink.
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Real-world monitoring of arrhythmias and ICD shock therapy
This registry will follow people getting an implantable cardioverter‑defibrillator to see which patients receive appropriate or inappropriate shocks and why.
Quick answers
How many clinical trials run by Fondazione IRCCS Policlinico San Matteo di Pavia are recruiting right now?
96, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 6 countries. The most sites are in Italy (96 trials), Switzerland (2 trials), Germany (1 trial), Netherlands (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.