Measuring the shape and strength of the ascending aorta in patients having heart surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project collects samples of the ascending aorta removed during routine cardiac operations and sends leftover tissue for anonymous mechanical testing at the University of Pavia's engineering department. Patients undergoing ascending aorta replacement form the primary group, while patients undergoing heart transplantation or donor aortas serve as controls. Specimen collection follows standard surgical practice and does not change clinical care or decision-making, and patients with high biological hazard infections (HCV/HIV) are excluded. Results will compare morphological and mechanical properties across groups to clarify links between clinical features and aortic wall behavior.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients undergoing surgery including ascending aorta replacement at our Department and/or heart transplantation

Exclusion Criteria:

* Patients with biological hazard (HBC/HIV +)

Where it's running

• Fondazione IRCCS Policlinico San Matteo di Pavia
  Pavia, Lombardy, Italy Recruiting

Study contacts

• Study coordinator: Pasquale Totaro, MD
• Email: p.totaro@matteo.pv.it
• Phone: 3283678762

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.