Neonatal Echovirus 11 infections in Italy: virological, genomic and clinical insights

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project collects respiratory and residual clinical samples from consecutive neonates admitted to the NICU at Fondazione IRCCS Policlinico San Matteo in Pavia. Samples with sufficient volume (≥1 mL nasal swab) will undergo virological characterization, including next-generation sequencing to obtain viral genomes. Genomic data will be linked with clinical and epidemiological information to identify viral variants, transmission patterns, and associations with severe outcomes such as sepsis, respiratory complications, or gastrointestinal disease. No investigational treatments are given; the work is laboratory and data-driven to improve understanding of neonatal enterovirus infections.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Samples from consecutive neonates admitted to neonatal intensive care unit.

Exclusion Criteria:

Insufficient residual samples (volume less than 1 mL of nasal swab) will be excluded from the study

Where it's running

• Fondazione IRCCS Policlinico San Matteo
  Pavia, Lombardy, Italy Recruiting

Study contacts

• Study coordinator: Antonio Piralla
• Email: a.piralla@smatteo.pv.it
• Phone: +390382502420

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.