Immune‑blot band patterns in inactive liver cysts from cystic echinococcosis
Comparison of Immunoblotting Bands Pattern in Patients With Treated Versus Untreated Inactive Echinococcal Cysts of the Liver
This will test whether immunoblot band patterns differ between treated and untreated adults with inactive echinococcal cysts in the liver.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Fondazione IRCCS Policlinico San Matteo di Pavia Academic / other |
| Locations | 1 site (Pavia, PV) |
| Trial ID | NCT07333612 on ClinicalTrials.gov |
What this trial studies
Researchers will collect blood samples and clinical data from adults with hepatic cystic echinococcosis who have had at least two clinical evaluations, comparing those who received treatment to those who remain untreated. Immunoblotting will be performed on serum to characterize antibody band patterns associated with inactive liver cysts. This is an observational, single‑center protocol conducted at Fondazione IRCCS Policlinico San Matteo di Pavia with no interventions assigned by the study. The aim is to see if distinct immunoblot signatures correlate with treated versus untreated inactive hepatic cysts.
Who should consider this trial
Good fit: Adults over 18 with hepatic cystic echinococcosis who have undergone at least two clinical evaluations and have inactive liver cysts are the intended participants.
Not a fit: People with echinococcal cysts outside the liver, children under 18, or those with fewer than two clinical evaluations are not eligible and unlikely to benefit from this protocol.
Why it matters
Potential benefit: If successful, this could provide a noninvasive laboratory marker to help monitor treatment response and distinguish treated from untreated inactive liver cysts.
How similar studies have performed: Immunoblotting has been used to detect antibodies in echinococcosis, but using specific band patterns to separate treated versus untreated inactive hepatic cysts is relatively novel with limited prior evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Only Hepatic echinococcal cysts * Age \> 18 years * At leat 2 clinical evaluation Exclusion Criteria: * different location of echinococcal cysts * Age \< 18 years --less then 2 clinical evalutation
Where this trial is running
Pavia, PV
- Fondazione IRCCS Policlinico San Matteo di Pavia — Pavia, Pv, Italy (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.