Characterizing T-cell responses to arbovirus infections using ELISpot tests

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project will enroll adults with suspected arbovirus infection at Fondazione IRCCS Policlinico San Matteo in Pavia and collect blood samples for immunological analysis. Researchers will use ELISpot and related assays to measure virus-specific T-cell responses and compare results with serology and clinical information. The work will include endemic and imported arboviruses such as WNV, TOSV, SFSV, SFNV, USUV, TBEV, CHIKV, DENV, ZIKV, YFV, and JEV. Results aim to map cellular immune profiles that could inform diagnosis and surveillance strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults 18 years- old and over; all sexes will be eligible for the study;
* Suspected arbovirus infection
* Written informed consent and any required authorization obtained from the participant prior to performing any protocol-related procedures;

Exclusion Criteria:

* Any condition that might compromise safety or interfere with study results.
* All other conditions not present in the inclusion criteria.

Where it's running

• Fondazione IRCCS Policlinico San Matteo
  Pavia, Lombardy, Italy Recruiting

Study contacts

• Study coordinator: Baldanti
• Email: segreteria.virologia@smatteo.pv.it
• Phone: +390382502420

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.