Tracking mastocytosis from childhood to adulthood
Official title: Mastocytosis From Pediatric Age to Adulthood: Local Registry of Cutaneous and Systemic Mastocytosis
Run by Fondazione IRCCS Policlinico San Matteo di Pavia · NCT07142473 · Data updated 2026-11-12
This hospital registry will collect clinical, laboratory, and genetic information from children and adults with cutaneous or systemic mastocytosis seen in Pavia to see how the disease changes over time and what predicts outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 6 Years and up |
| Sex | All |
| Enrollment | 600 (estimated) |
| Sponsor | Fondazione IRCCS Policlinico San Matteo di Pavia Academic / other |
| Locations | 1 site (Pavia, Pavia) |
| Status | Recruiting |
| Started | January 26, 2024 |
| Main results expected | January 26, 2034 |
| Study ends | January 26, 2034 |
| Registry record updated | August 26, 2025 |
| Trial ID | NCT07142473 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children and adults diagnosed with cutaneous or systemic mastocytosis who attend the Dermatology Outpatient Clinics at Fondazione IRCCS Policlinico San Matteo and consent to data collection.
✕Probably not a fit
Patients who are not treated or followed at the Pavia center, or whose disease subtypes are not represented in the registry, are unlikely to receive direct benefit from this project.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a single-center longitudinal registry collecting both retrospective and prospective data on patients with cutaneous and systemic mastocytosis seen at the Dermatology Unit of Fondazione IRCCS Policlinico San Matteo. Clinical records, laboratory results, histology/immunohistochemistry, and available genetic/molecular data will be compiled and analyzed. The project aims to describe epidemiology, clinical features, serological and hematological findings, and molecular markers across age groups. Identified prognostic variables may support more personalized monitoring and treatment approaches.
Why it matters
Potential benefit: If successful, the registry could improve understanding of disease course and prognostic markers, helping clinicians tailor monitoring and treatment to individual patients.
How similar studies have gone: Other national and international mastocytosis registries have previously helped clarify natural history and identify prognostic features, so this approach has precedent and utility.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: \- Cutaneous or systemic mastocytosis diagnosys attending the Dermatology Outpatient Clinics of the UOC Dermatology Unit Fondazione IRCCS Policlinico San Matteo
Where it's running
-
SC Dermatologia, Fondazione IRCCS Policlinico San Matteo
Pavia, Pavia, Italy Recruiting
Study contacts
- Study coordinator: Valeria Brazzelli, MD
- Email: v.brazzelli@smatteo.pv.it
- Phone: 03820503794
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.