San Matteo Endocarditis Registry (STEADY)
Official title: San Matteo Endocarditis Registry STEADY
Run by Fondazione IRCCS Policlinico San Matteo di Pavia · NCT07346222 · Data updated 2026-11-12
This registry collects health and treatment information from people diagnosed with infective endocarditis at San Matteo to better understand their care and outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 418 (estimated) |
| Sponsor | Fondazione IRCCS Policlinico San Matteo di Pavia Academic / other |
| Locations | 1 site (Pavia, Lombardy) |
| Status | Recruiting |
| Started | August 20, 2020 |
| Main results expected | November 13, 2025 |
| Study ends | November 13, 2030 |
| Registry record updated | January 16, 2026 |
| Trial ID | NCT07346222 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
People admitted to Fondazione IRCCS Policlinico San Matteo in Pavia between January 1, 2009 and December 31, 2029 with a diagnosis of infective endocarditis according to the modified Duke criteria.
✕Probably not a fit
Patients treated outside San Matteo, those without a confirmed diagnosis by the modified Duke criteria, or those seeking immediate experimental therapies are unlikely to gain direct benefit from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a single-center observational registry collecting clinical, microbiological, imaging, treatment, and outcome data for patients with infective endocarditis admitted to Fondazione IRCCS Policlinico San Matteo. It includes cases from January 1, 2009 through December 31, 2029 identified by the modified Duke criteria. Data will be extracted from medical records and entered into a database to characterize presentation, management choices (including medical and surgical therapy), microbiology, and short- and long-term outcomes. The registry aims to create a comprehensive dataset to inform clinical practice and future research on infective endocarditis.
Why it matters
Potential benefit: If successful, the registry could help clinicians improve diagnosis and treatment decisions for people with infective endocarditis and guide future research.
How similar studies have gone: Other single-center and multicenter endocarditis registries have identified risk factors and outcome patterns, so the registry approach is established and has been useful in improving care.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients admitted from 1stJannary 2009 to 31 Dec 2029 to the Fondazione IRCCS Policlinico San Matteo with a diagnosis of IE according to modified Duke criteria Exclusion Criteria: \-
Where it's running
-
Fondazione IRCCS Policlinico San Matteo di Pavia
Pavia, Lombardy, Italy Recruiting
Study contacts
- Study coordinator: Elena Maria Seminari
- Email: E.Seminari@smatteo.pv.it
- Phone: +39 0382 502646
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Continuous versus standard intermittent ampicillin plus ceftriaxone for Enterococcus faecalis endocarditis
This study will see if giving ampicillin plus ceftriaxone as a continuous infusion works as well and is as safe as the usual intermittent dosing for adults with Enterococcus faecalis infective endocarditis.
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Comparing oral antibiotics to outpatient parenteral therapy for infective endocarditis
This study is testing if taking oral antibiotics at home is just as effective as getting antibiotics through an IV for patients with left-sided infective endocarditis.
-
Prognosis of Infectious Endocarditis
This study looks at how infectious endocarditis affects people with both natural and artificial heart valves to better understand the disease and improve treatment outcomes.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.